Traci A Wilgus,Sashwati Roy,Jodi C McDaniel
Traci A Wilgus
Significance: Neutrophils are one of the most abundant cells of the immune system and they are extremely active during the repair of cutaneous wounds. In general, the antimicrobial activity of neutrophils is effective and...
Cardiac Progenitor Cells in Myocardial Infarction Wound Healing: A Critical Review [0.03%]
心肌梗死伤口愈合中心肌祖细胞的研究：批判性综述
Michael W Morris Jr,Kenneth W Liechty
Michael W Morris Jr
Significance: Coronary artery disease is a major cause of morbidity and mortality as the loss of functional myocardium drives progressive ventricular remodeling and subsequent heart failure. Medical management has signifi...
M Noelle Knight,Kurt D Hankenson
M Noelle Knight
Significance: Mesenchymal stem cells (MSCs) play a key role in fracture repair by differentiating to become bone-forming osteoblasts and cartilage-forming chondrocytes. Cartilage then serves as a template for additional b...
Ruoxue Feng,Chistopher Lengner
Ruoxue Feng
Significance: In this review, we summarize the current literature regarding the isolation and characterization of dental tissue-derived stem cells and address the potential of these cell types for use in regenerative cell...
The Role of Endothelial Progenitor Cells in Postnatal Vasculogenesis: Implications for Therapeutic Neovascularization and Wound Healing [0.03%]
内皮祖细胞在出生后血管生成中的作用及其对治疗性新生血管和伤口愈合的意义
Swathi Balaji,Alice King,Timothy M Crombleholme et al.
Swathi Balaji et al.
Significance: Postnatal vasculogenesis mediated via endothelial progenitor cells (EPCs) contributes to re-endothelialization and augments neovascularization after ischemia and tissue injury, providing a novel therapeutic ...
Makoto Senoo
Makoto Senoo
Significance: The skin interfollicular epidermis (IFE) is an organism's first line of defense against a harmful environment and physical damage. During homeostasis and wound repair, the IFE is rejuvenated constantly by IF...
Interactions of the Extracellular Matrix and Progenitor Cells in Cutaneous Wound Healing [0.03%]
表皮伤口愈合中细胞外基质与干细胞的相互作用
Susan W Volk,Syed Amir Iqbal,Ardeshir Bayat
Susan W Volk
Significance: Both chronic wounds and excessive scar formation after cutaneous injury create a formidable clinical problem resulting in considerable morbidity and healthcare expenditure. The deposition and remodeling of e...
Axolotl as a Model to Study Scarless Wound Healing in Vertebrates: Role of the Transforming Growth Factor Beta Signaling Pathway [0.03%]
墨西哥钝头螈作为研究脊椎动物无瘢痕伤口愈合的模型：转化生长因子β信号通路的作用
Jean-François Denis,Mathieu Lévesque,Simon D Tran et al.
Jean-François Denis et al.
Significance: The skin is our largest organ, with the primary role of protection against assaults from the outside world. It also suffers frequent damage, from minor scrapes to, more rarely, complete destruction such as i...
Focal Adhesion Kinase: A Key Mediator of Transforming Growth Factor Beta Signaling in Fibroblasts [0.03%]
肌纤维母细胞中黏着斑激酶是转化生长因子β信号通路的关键介质
Andrew Leask
Andrew Leask
Significance: There is no effective drug therapy for scarring and fibrotic disease. The cytokine transforming growth factor beta (TGF-β) promotes tissue repair, but its excessive action can lead to over exuberant scarrin...
Integrins as Modulators of Transforming Growth Factor Beta Signaling in Dermal Fibroblasts During Skin Regeneration After Injury [0.03%]
损伤后皮肤再生过程中表皮纤维细胞中整合素调节转化生长因子β信号转导的功能研究
Stellar Boo,Lina Dagnino
Stellar Boo
Significance: Abnormal wound repair results from disorders in granulation tissue remodeling, and can lead to hypertrophic scarring and fibrosis. Excessive scarring can compromise tissue function and decrease tissue resist...