Weixue Jin,Danyang Ren,Meirong Yu et al.
Weixue Jin et al.
Significance: Refractory wounds are complicated multistep biological processes that can lead to severe complications in patients. Selective autophagy plays a crucial role in precisely controlling the quality of intracellular components and ...
Lulu Sun,Ruinan Hao,Kelly Van Van et al.
Lulu Sun et al.
Significance: Wound healing is a complex, tightly regulated process involving a range of enzymes, growth factors, and cytokines that coordinate cellular activities essential for tissue repair and wound closure. However, in cases of extensiv...
Multi-State Modeling of Pressure Injury Staging Transition Trajectories to Inform Next-Generation Clinical Decision Support [0.03%]
多状态压力性损伤分期过渡轨迹模型在下一代临床决策支持中的应用研究
Wenyu Song,Min-Jeoung Kang,Luwei Liu et al.
Wenyu Song et al.
Objective: This study aimed to evaluate the location-specific and time-sensitive trajectories of pressure injuries (PrIs) stages using real-world electronic health record (EHR) datasets. Approach: Using a dataset of 29,475 patients with rec...
Henry C Hsia,Elof Eriksson,Geoffrey C Gurtner et al.
Henry C Hsia et al.
Significance: The Wound Healing Foundation recognized the need for consensus-based unbiased recommendations for the treatment of wounds. Consensus statements on the treatment of chronic wounds and acute wounds have been developed and publis...
Han Wu,Jiunn-Der Liao,Shin-Chen Pan et al.
Han Wu et al.
Plasma medicine offers an innovative and advanced physical approach to wound care that uniquely combines wound antimicrobial effects (primary goal) and accelerated regeneration of injured tissue (secondary goal). This review explores its tr...
Diabetic Wound Vasculopathy and Neuropathy: Spotlight on Wound Lipid Signaling [0.03%]
糖尿病伤口血管病变和神经病变：关于伤口脂质信号的焦点研究
Theja Bhamidipati,John P Hajj,Nehal I Ghoneim et al.
Theja Bhamidipati et al.
Significance: Skin lipids are essential for various skin functions including maintaining barrier integrity, regulating hydration, and providing protection against microbes and inflammatory irritants. Along with skin health, the role of lipi...
The Efficacy of Negative Pressure Wound Therapy Combined with Topical Oxygen Therapy in Treating Chronic Refractory Wounds: A Systematic Review and Meta-Analysis [0.03%]
负压联合局部氧疗治疗难治性慢性创面疗效的系统评价和 meta 分析
Junwei Su,Dong Zhang,Jincheng Du et al.
Junwei Su et al.
Objective: To evaluate the clinical efficacy of negative pressure wound therapy (NPWT) combined with topical oxygen therapy (TOT) for chronic refractory wounds (CRWs), addressing potential hypoxia limitation of NPWT through oxygen supplemen...
The Correlation Between Wound Bed Preparation and Wound Closure in Venous Leg Ulcers: A Post Hoc Analysis of the ChronEx Multicenter Randomized Controlled Trial [0.03%]
静脉腿部溃疡伤口愈合与创面准备相关性的时相特点：ChronEx多中心随机对照临床试验的事后分析结果
Marissa J Carter,Robert J Snyder,Keren David Zarbiv et al.
Marissa J Carter et al.
Objective: This post hoc analysis determined the correlation between wound bed preparation (WBP), defined as complete debridement of nonviable tissue and complete granulation tissue coverage, and wound closure, using data from a published, ...
Chandan K Sen,Andrew Friday,Savita Khanna et al.
Chandan K Sen et al.
Collagen, the most abundant structural protein in the human body, plays a vital role in wound healing, tissue repair, and skin integrity. Collagen-based products-ranging from wound dressings, skin substitutes, dental and orthopedic scaffold...
Ashu Rastogi,Rahul Gupta,Jayaditya Ghosh et al.
Ashu Rastogi et al.
Significance: The prevalence of diabetes is increasing and so is diabetic foot disease (DFD). DFD encompasses diabetic foot ulcer (DFU), which is a major global health problem. DFD contributes to increased morbidity (reduced quality of life...