Flexible Pressure Sensors for Optimizing Pressure Garment Therapy in Periarticular Scar Treatment: Preclinical and Clinical Applications [0.03%]
用于改善 periarticular 疤痕治疗中压力衣疗法的压力传感器：临床前与临床应用
Jia Xu,Yaxin Xue,Wei Xu et al.
Jia Xu et al.
Objective: Pressure garment therapy is a common strategy for controlling hypertrophic scars; however, insufficient pressure due to reduced elasticity or joint movement limits its effectiveness around joints. The FlexiForce B201 pressure sen...
Bridging the Gap: Contemporary Paradigms in Nerve Scaffolds and Regeneration [0.03%]
缩小差距：神经支架与再生的现代范式
Charles D Hwang,Seamus P Caragher,Rebekah J Bihun et al.
Charles D Hwang et al.
Peripheral nerve injuries, especially those with complete transection of major nerves, create significant morbidity including debilitating pain, loss of protective haptic feedback, and impaired volitional control of musculature. The societa...
Using Three-Dimensional Bioprinting to Generate Realistic Models of Wound Healing [0.03%]
利用三维生物打印制造逼真的伤口愈合模型
Giselle Y Díaz,Victor A da Silva,Farnoosh Kalantarnia et al.
Giselle Y Díaz et al.
Significance: The skin serves as the primary defense against external stimuli, making it vulnerable to damage. Injuries can cause a dysregulated environment, resulting in chronic inflammation and inhibition of cell proliferation and migrati...
Prediction Models for Intraoperative Acquired Pressure Injury of Adults: A Systematic Review and Critical Appraisal [0.03%]
成人术中获得性压疮预测模型的系统评价与分析
Yihong Xu,Han Zhao,Shuang Wu et al.
Yihong Xu et al.
Significance: Postoperative Pressure Injuries (PIs) present unique risks, requiring dedicated research for accurate assessment. Despite the increasing number of Intraoperative Acquired Pressure Injury (IAPI) prediction models, their risk of...
An Open-Label, Interventional, Prospective, Real-World Evidence Study to Evaluate a Multimodal Wound Matrix in Patients with Refractory Wounds [0.03%]
一项开放性干预前瞻性真实世界证据研究，在难治性创面患者中评价多功能伤口敷料的效果
Yadwinder Dhillon,Gerit Mulder,Keyur Patel et al.
Yadwinder Dhillon et al.
Objective: The objective of this open-label, interventional, prospective clinical study was to evaluate the effectiveness of a multimodal wound matrix (MWM) in moving chronic, nonhealing wounds that had failed prior therapies onto a healing...
Prevalent Types of Peristomal Skin Damage During Chemoradiotherapy and Their Risk Factors [0.03%]
放化疗期间造口周围常见皮肤损害及危险因素分析
Yi Chen,Yan Lu,LiJuan Zhang et al.
Yi Chen et al.
Significance: Colorectal cancer is currently ranked third in terms of the global cancer incidence. Enterostomy, a common surgical procedure for colorectal cancer treatment, creates a temporary or permanent stoma in the abdominal wall for wa...
Structured Exercise Therapy Increases Endogenous Antioxidants to Repair Muscle Strength and Health in Porcine Ischemic Myopathy Model of Peripheral Artery Disease [0.03%]
结构化运动疗法通过增加内源性抗氧化剂来修复外周动脉疾病猪缺血性肌病模型的肌肉力量和健康状况
Carson Hoffmann,Dennis Foster,Emma Fletcher et al.
Carson Hoffmann et al.
Objective: The mechanisms of structured exercise therapy (SET) in peripheral artery disease (PAD) are not clear. We have developed an SET module for our large animal model of ischemic myopathy. We hypothesized that SET would increase muscle...
Single-Cell Proteomics Uncovers Dual Traits of Dermal Sheath Cells in Wound Repair [0.03%]
单细胞蛋白质组学揭示真皮鞘细胞在伤口修复中的双重特性
Bing Zhu,Yaojun Lu,Xinyue Kang et al.
Bing Zhu et al.
Wound healing is a dynamic process involving multiple cell types and signaling pathways. Dermal sheath cells (DSCs), residing surrounding hair follicles, play a critical role in tissue repair, yet their regulatory mechanisms remain unclear....
Treatment of Surgical Scars with Fractional Carbon Dioxide (CO2) Laser: A Randomized Controlled Trial [0.03%]
分数二氧化碳激光治疗手术疤痕的疗效：随机对照试验
Liang Chen,Han Xu,Qiu Yu Wang et al.
Liang Chen et al.
Object: The aim of this study was to compare the long-term effects of fractional carbon dioxide (CO2) laser treatment with traditional therapy on surgical scars by analyzing and comparing observational indicators. Approach: A randomized con...
Effects of a New Enzymatic Debrider (SN514-066b) on Eschar Protein Digestion, Burn Wound Debridement, and Healthy Skin Irritation [0.03%]
一种新型酶脱bridder(SN514-066b)对焦痂蛋白消化、烧伤创面脱bridment及健康皮肤刺激性的影响
Herbert B Slade,Barry T Reece,Nick D McCoy et al.
Herbert B Slade et al.
Objective: SN514 is a thermolysin-like enzyme under development as a debrider. Preclinical and non-clinical studies supported a first in human healthy volunteer study to predict the need for protection of periwound skin. Approach: Pharmacol...