Management of Infected Wounds: A Wound Healing Foundation Consensus Statement [0.03%]
感染性创面的处理：伤口愈合基金会共识声明
Nicolás Cortés-Penfield,Benjamin A Lipsky,Elof Eriksson et al.
Nicolás Cortés-Penfield et al.
The Wound Healing Foundation (WHF) previously organized consensus panels on the management of chronic wounds (2022), acute wounds (2024), and diabetic wounds (2025). This WHF consensus statement, authored by a global interdisciplinary panel...
Predicting Harm: A Systematic Review of Pediatric Pressure Injury Models and Their Clinical Shortcomings [0.03%]
预测压力性损伤的模型及其临床不足的系统综述——儿童视角
Xiaojie Zhang,Zhichao Yang,Xiuping Li et al.
Xiaojie Zhang et al.
Significance: Pediatric pressure injuries (PIs) are a distinct and preventable clinical challenge, yet risk prediction models tailored to children remain underdeveloped. This systematic review critically evaluates existin...
Development and Validation of a Novel Risk Prediction Model for Incident Diabetic Foot Complications: A Large, Longitudinal, Population-Based Machine Learning Study [0.03%]
新型糖尿病足并发症发生率预测模型的开发和验证：一项大规模纵向人群机器学习研究
Ziyun Li,Aomingyang Wang,Ruilin Wang et al.
Ziyun Li et al.
Objective: Diabetic foot complications (DFCs) are common diabetes complications. Existing tools for predicting incident DFCs remain insufficient. This study aimed to develop and validate a novel machine learning-based mod...
Diabetic Foot Ulcers as a Marker of Systemic Disease: Long-Term Survival, Limb Loss, and Economic Impact in a Large Real-World Cohort [0.03%]
糖尿病足溃疡作为系统性疾病标志的长期生存、截肢和经济影响现实世界队列研究
María Lourdes Del Río-Solá,Carlos García Padrón,Clara de la Torre Casaseca et al.
María Lourdes Del Río-Solá et al.
Background: Diabetic foot ulcers (DFUs) represent one of the most severe complications of diabetes mellitus and are associated with limb loss, excess mortality, and substantial health care costs. Although DFUs are often a...
Temporal In Vitro Models of Skin Wound Healing Components: A Cell-Specific Framework for Acute and Chronic Repair Mechanisms [0.03%]
皮肤伤口愈合成分的时空体外模型：急性期和慢性期修复机制的细胞特异性框架
Dipti Kalshetti,Mahmud Amin,Ridham Varsani et al.
Dipti Kalshetti et al.
Significance: Wound healing is as much about opportunity (Gk. Karios) and sequence (Gk. Chronos). The sequential healing responses involve concerted responses of cells of various lineages along with both soluble (cytokine...
The Diabetic Foot Consortium Biomarker Platform Study: A New Approach to Advance Diabetic Foot Ulcer Healing [0.03%]
糖尿病足联盟生物标志物平台研究：促进糖尿病足溃疡愈合的新方法
Brian M Schmidt,Cathie Spino,Teresa L Z Jones et al.
Brian M Schmidt et al.
Objective: Platform studies are an innovative clinical trial design to evaluate multiple potential therapies simultaneously using a master protocol framework for more rapid discovery of critical new disease-modifying ther...
The Functionality of High-Density Lipoproteins Is Impaired in People with Diabetes Who Require Minor Amputations [0.03%]
糖尿病合并需要小截肢患者的高密度脂蛋白功能受损
Zahra Lotfollahi,Emma L Solly,Joanne T M Tan et al.
Zahra Lotfollahi et al.
Objective: High-density lipoprotein (HDL) functionality is emerging as a novel predictor of disease outcomes. The role of HDL functionality in patients with diabetes-related amputations is unexplored. We aimed to assess c...
Protein-Based Nutrition for Chronic Wounds: A Clinician's Guide to Patient Selection, Dosing, Monitoring, and Outcomes [0.03%]
基于蛋白的营养素在慢性伤口治疗中的应用——临床医师选择患者、用药剂量、监测及预后的指导手册
Zilong Tan,Yi Ru,Caiyun Zhang et al.
Zilong Tan et al.
Significance: Chronic wounds remain a major global health burden and often stall despite guideline-based care because of persistent inflammation, oxidative stress, impaired perfusion, and dysregulated extracellular matrix...
Overcoming Challenges in Wound Infection: Biofilm and Antimicrobial Resistance [0.03%]
应对伤口感染的挑战：生物膜与抗菌药物耐药性
Markus Rothmaier,Matthew J Hardman,Bithi Chatterjee et al.
Markus Rothmaier et al.
Significance: Chronic wounds represent a growing clinical and economic burden, affecting 1-2% of the global population, with prevalence expected to rise due to aging and increasing rates of diabetes, obesity, and vascular...
Partnering with Communities to Improve Diabetic Foot Ulcer Care in High-Risk Populations [0.03%]
与社区合作改善高风险人群糖尿病足溃疡护理
Nancy Gauvin,Breana Wayne,Shomita S Mathew-Steiner et al.
Nancy Gauvin et al.
Background: Diabetic foot ulcers (DFUs) remain one of the most devastating complications of diabetes, accounting for over 80% of nontraumatic amputations and contributing to a 5-year mortality rate exceeding 30%. Despite ...