Inhibition of α-Synuclein Misfolding into β-Sheet Domains on Medium-Sized Gold Nanoclusters: Evidence from Enhanced Sampling MD Simulations [0.03%]
基于中等大小金纳米簇的α-突触核蛋白错折叠成β-片层结构的抑制：从增强采样MD模拟得到的证据
Shuai Gong,Guanbin Gao,Taolei Sun et al.
Shuai Gong et al.
Targeting Parkinson's disease (PD) related protein, α-synuclein (αS), via gold nanoclusters (AuNCs) has received considerable attention in PD treatments, but its molecular basis on the initial interactions between αS and AuNCs remains el...
Room-Temperature Synthesis of a Fluorine-Functionalized Nanoporous Organic Polymer for Highly Efficient SF6 Adsorption and Separation [0.03%]
一种室温合成的氟功能化纳米多孔有机聚合物高效吸附和分离SF_6气体
Sihan Tong,Lu Yao,Qilin Wang et al.
Sihan Tong et al.
Sulfur hexafluoride (SF6) is widely used in the power industry and significantly contributes to the greenhouse effect, necessitating the development of efficient materials for SF6 capture, particularly fluorine-containing materials. However...
Effects of a Mechanically Interlocked Structure on Ionic Conductivity in Polyrotaxane-Based Polymer Electrolytes [0.03%]
基于聚轮烷聚合物电解质中机械互锁结构对离子电导率的影响
Bitgaram Kim,Eunji Lee,Ji-Hun Seo
Bitgaram Kim
Polyrotaxane (PR) is a mechanically interlocked polymer (MIP) utilized as an electrolyte because of its distinctive property of dynamic molecular mobility. While numerous studies have concentrated on modifying external properties to decreas...
Controlled Fabrication of Distinct Nanostructures from Discrete Oligourethanes via Thermal Annealing [0.03%]
热处理法制备寡聚尿素的亚稳纳米结构
Qiangqiang Shi,Yong Yu,Lingxiao Guo et al.
Qiangqiang Shi et al.
The self-assembly of sequence-defined polymers (SDPs) enables the formation of a diverse array of nanostructures; however, the construction of complex hierarchical structures via thermal annealing from SDPs remains relatively unexplored. In...
Alkyl-Substituted Polycaprolactone Poly(urethane-urea)s as Mechanically Competitive and Chemically Recyclable Materials [0.03%]
具有烷基取代聚己内酯的聚氨酯脲作为高性能可回收材料
Derek C Batiste,Michaela R Pfau-Cloud,Hee Joong Kim et al.
Derek C Batiste et al.
We report the mechanical performance and chemical recycling advantages of implementing alkyl-substituted poly(ε-caprolactones) (PCLs) as soft segments in thermoplastic poly(urethane-urea) (TPUU) materials. Poly(4-methylcaprolactone) (P4MCL...
Highly Alternating Copolymer of [1.1.1]Propellane and Perfluoro Vinyl Ether: Forming a Hydrophobic and Oleophobic Surface with <50% Fluorine Monomer Content [0.03%]
[1.1.1]盘烷与全氟乙烯基醚交替共聚物：超疏水低表面能涂层制备及性能研究
Mizuki Okuda,Midori Akiyama,Kosuke Funahashi et al.
Mizuki Okuda et al.
Utilizing the unique properties of fluorine substitution is an effective strategy for constructing highly functional materials. Here, we synthesized a novel copolymer composed of [1.1.1]propellane and perfluoro(propyl vinyl ether) (PPVE), r...
Functionalization and Repurposing of Polypropylene to a Thermoset Polyurethane [0.03%]
功能性改性及将聚丙烯重塑为热固型聚氨酯塑料
Ronard Herrera Monegro,Ramanan Krishnamoorti,Megan L Robertson
Ronard Herrera Monegro
Developing effective recycling pathways for polyolefin waste, enabling a move to a circular economy, is an imperative that must be met. Postuse modification has shown promising results in upcycling polyolefins, removing the limitation of in...
Preparation of Disulfide/Trisulfide Core-Cross-Linked Polycarbonate Nanocarriers for Intracellular Reduction-Triggered Drug Release [0.03%]
用于细胞内还原触发药物释放的二硫化物/三硫化物核心交联形聚碳酸酯纳米载体的制备
Jiye Zhao,Dongdong Wang,Xi Zhang et al.
Jiye Zhao et al.
Polymeric nanocarriers have attracted significant attention in the field of anticancer drug delivery due to their unique advantages. However, designing nanocarriers that can maintain stability in the bloodstream while achieving specific dru...
Fast, Regioselective Aminolysis of Tetrasubstituted Cyclic Carbonates and Application to Recyclable Thermoplastics and Thermosets [0.03%]
快速区域选择性四取代环碳酸酯氨解反应及在可循环利用热塑性和热固性塑料中的应用
Thomas Habets,Raphaël Méreau,Fabiana Siragusa et al.
Thomas Habets et al.
Herein, the long-standing challenge of the ring-opening aminolysis of CO2-derived tetrasubstituted cyclic carbonates at room temperature (r.T) is overcome under catalyst-free conditions. Molecular design of the cyclic carbonate by substitut...
Multifunctional Polymer Synthesis via Sequential Postpolymerization Modification Using a Single Aldehyde Repeat Unit: Allylation and Orthogonal Esterification and Thiol-ene Reaction [0.03%]
通过单醛重复单元的连续聚合物后修饰合成多功能聚合物： allylation和正交酯化及硫醇-烯反应
Hyo Won Lee,Jeung Gon Kim
Hyo Won Lee
Herein, we present a highly efficient method for synthesizing multifunctional polymers. This method involves the sequential postpolymerization modification (PPM) of a highly reactive aldehyde polymer. We introduce an allylic alcohol functio...