Venetoclax-based low-intensity therapy in pediatric AML: A viable option for chemotherapy-intolerant patients [0.03%]
Nidhi Dhariwal,Shyam Srinivasan
Nidhi Dhariwal
Childhood acute myeloid leukemia (AML) comprises 15-20% of pediatric leukemias and carries promising survival rates (60-70%) in high-income countries with use of intensive chemotherapy. This is associated with high treatment-related mortali...
Immunological, hematological and biochemical benefits of adjuvant nigella sativa to pharmacotherapy in immune thrombocytopenic purpura patients [0.03%]
Mohamed Abdelshafy,Mohamed El Shanshory,Khaled Shahat et al.
Mohamed Abdelshafy et al.
Background: Patients having acute and chronic immune thrombocytopenic purpura (ITP) suffer from thrombocytopenia, decreased T regulatory lymphocytes (causing immunological tolerance) and abnormal biochemistry (increased i...
Kalyan Chaliki,Mohammad Reza Movahed,Mehrtash Hashemzadeh et al.
Kalyan Chaliki et al.
Objectives: Heparin is widely used as an anticoagulant in hospitals. Ventilated patients on heparin are at a higher risk of developing heparin-induced thrombocytopenia (HIT). This study aims to examine the effect of HIT o...
Is the coexistence of diabetes and hypertension liable for a higher risk of cardiovascular disorders among Saudis? [0.03%]
糖尿病和高血压共存是沙特人心血管疾病高发的原因吗？
Fayez Saud Alreshidi,Eldisugi Hassan Mohammed Humida,Hussain Gadelkarim Ahmed
Fayez Saud Alreshidi
Background: Cardiovascular diseases (CVDs) are experiencing a notable increase globally, largely influenced by the related rise in risk factors, including type 2 diabetes mellitus (T2DM) and hypertension (HTN). This study...
Assessing glucose 6-phosphate dehydrogenase activity in children with acute lymphoblastic leukemia and its relationship to disease activity [0.03%]
评估急性淋巴细胞白血病儿童葡萄糖-6-磷酸脱氢酶活性及其与疾病活动度的关系
Omid Reza Zekavat,Nader Shakibazad,Seyed Javad Dehghani et al.
Omid Reza Zekavat et al.
Objective: Glucose 6-phosphate dehydrogenase (G6PD) activity of red blood cells (RBC) may be helpful as a prognostic factor and a probable predictive indicator of disease activity in children with acute lymphoblastic leuk...
Rosai-Dorfman-Destombes disease in an elderly man. A case of necrosis in the lymph node [0.03%]
Rosai-Dorfman-Destombes病一例老年男性病例及淋巴结坏死情况报告
Yasuhiro Kazuma,Naoko Ishizaki,Shoki Morito et al.
Yasuhiro Kazuma et al.
Objectives: Rosai-Dorfman-Destombes disease (RDD), often associated with autoimmune disease, is rare in the elderly. We report a 79-year-old Japanese man with RDD, who had been treated for non-specific interstitial pneumo...
Leena Gupta,Smeeta Gajendra,Akash Kumar Jha et al.
Leena Gupta et al.
Acute erythroid leukemia (AEL) is an extremely rare subtype of acute myeloid leukemia (AML), accounting for less than 1% of AML cases. It predominantly affects older adults and is characterized by a proliferation of erythroid precursors, ty...
Prognostic value of platelet volume indices in heart failure: a systematic review and meta-analysis [0.03%]
血小板体积指数在心力衰竭中的预后价值：系统评价和meta分析
Amir Parsa Abhari,Farzad Adelparvar,Parastesh Rezvanian et al.
Amir Parsa Abhari et al.
Objectives: Heart failure (HF) is a complex condition with a substantial global prevalence and clinical burden. Prognostic biomarkers are essential for effective management. This study systematically reviews and synthesiz...
Deevyashali Parekh,Ali Bassir,Devashish Desai et al.
Deevyashali Parekh et al.
Background: Sitosterolemia is a rare inherited condition caused by elevated levels of plant sterols in the plasma, characterized by mutations in ABCG5 and ABCG8 genes. A scarce occurrence in this condition are hematologic...
Acute myolysis in patients on tyrosine kinase inhibitor therapy for chronic myeloid leukemia [0.03%]
慢性粒细胞白血病酪氨酸激酶抑制剂治疗患者的急性肌溶解
Jeffrey H Lipton
Jeffrey H Lipton
Patients on tyrosine kinase inhibitor therapy for chronic myeloid leukemia are often found to have elevated creatinine kinase levels on routine bloodwork and are asymptomatic. Here we report 4 cases of significant acute symptomatic jumps in...