Genetic dissection of morphological variation between cauliflower and a rapid cycling Brassica oleracea line [0.03%]
用基因方法解析花椰菜与快速轮回育种的芸苔种形态差异
Lan Shuan Shuang,Hugo Cuevas,Cornelia Lemke et al.
Lan Shuan Shuang et al.
To improve resolution to small genomic regions and sensitivity to small-effect loci in the identification of genetic factors conferring the enlarged inflorescence and other traits of cauliflower while also expediting further genetic dissect...
Concerning the eXclusion in human genomics: the choice of sex chromosome representation in the human genome drastically affects the number of identified variants [0.03%]
人类基因组中的性染色体排斥问题：人类基因组中性染色体的表示方式会显著影响识别到的变异数量的问题
Brendan J Pinto,Brian O&#x;Connor,Michael C Schatz et al.
Brendan J Pinto et al.
Over the past 30 years, a community of scientists has pieced together every base pair of the human reference genome from telomere to telomere. Interestingly, most human genomics studies omit more than 5% of the genome from their analyses. U...
Identity-by-descent-based estimation of the X chromosome effective population size with application to sex-specific demographic history [0.03%]
基于系谱相同的X染色体有效群体大小的估计及其在性别特异性人口史中的应用
Ruoyi Cai,Brian L Browning,Sharon R Browning
Ruoyi Cai
The effective size of a population (Ne) in the recent past can be estimated through analysis of identity-by-descent (IBD) segments. Several methods have been developed for estimating Ne from autosomal IBD segments, but no such effort has be...
RNA viruses, M satellites, chromosomal killer genes, and killer/nonkiller phenotypes in the 100-genomes S. cerevisiae strains [0.03%]
RNA病毒、M卫星、染色体杀手基因及酿酒酵母100个菌株中的杀手/非杀手表型
Sriram Vijayraghavan,Stanislav G Kozmin,Pooja K Strope et al.
Sriram Vijayraghavan et al.
We characterized previously identified RNA viruses (L-A, L-BC, 20S, and 23S), L-A-dependent M satellites (M1, M2, M28, and Mlus), and M satellite-dependent killer phenotypes in the Saccharomyces cerevisiae 100-genomes genetic resource popul...
A simulation study comparing advanced marker-assisted selection with genomic selection in tree breeding programs [0.03%]
一种模拟研究比较在林业育种项目中应用先进的标记辅助选择和基因组选择的效果
Bernd Degen,Niels A Müller
Bernd Degen
Advances in DNA sequencing technologies allow the sequencing of whole genomes of thousands of individuals and provide several million single nucleotide polymorphisms (SNPs) per individual. These data combined with precise and high-throughpu...
Josephine Bageritz,Niklas Krausse,Schayan Yousefian et al.
Josephine Bageritz et al.
Single-cell RNA sequencing has become an important method to identify cell types, delineate the trajectories of cell differentiation in whole organisms, and understand the heterogeneity in cellular responses. Nevertheless, sample collection...
FREQ-Seq2: a method for precise high-throughput combinatorial quantification of allele frequencies [0.03%]
精确的高通量组合等位基因频率量化方法FREQ-Seq2
Roy Zhao,Tamas Lukacsovich,Rebecca Gaut et al.
Roy Zhao et al.
The accurate determination of allele frequencies is crucially important across a wide range of problems in genetics, such as developing population genetic models, making inferences from genome-wide association studies, determining genetic r...
Tomotaka Tanaka,Toshiyuki Hayakawa,Kosuke M Teshima
Tomotaka Tanaka
Detection of natural selection is one of the main interests in population genetics. Thus, many tests have been developed for detecting natural selection using genomic data. Although it is recognized that the utility of tests depends on seve...
Gene-by-environment interactions influence the fitness cost of gene copy-number variation in yeast [0.03%]
基因型-环境互作影响酵母中的基因拷贝数变异的适应值代价
DeElegant Robinson,Elena Vanacloig-Pedros,Ruoyi Cai et al.
DeElegant Robinson et al.
Variation in gene copy number can alter gene expression and influence downstream phenotypes; thus copy-number variation provides a route for rapid evolution if the benefits outweigh the cost. We recently showed that genetic background signi...
Chromosome-level reference genome for North American bison (Bison bison) and variant database aids in identifying albino mutation [0.03%]
美洲野牛（Bison bison）染色体水平参考基因组及变异数据库有助于识别白化突变
Sam Stroupe,Carly Martone,Blake McCann et al.
Sam Stroupe et al.
We developed a highly contiguous chromosome-level reference genome for North American bison to provide a platform to evaluate the conservation, ecological, evolutionary, and population genomics of this species. Generated from a F1 hybrid be...