A Mid-Atlantic Brook Trout (Salvelinus fontinalis) genome to advance conservation and comparative genomics [0.03%]
一只阿巴拉契亚地区虹稚鱼（Salvelinus fontinalis）的基因组在保育和比较基因组学中的应用
Samuel W Rosenbaum,Merly Escalona,Samuel A May et al.
Samuel W Rosenbaum et al.
Brook Trout (Salvelinus fontinalis) are experiencing genomic erosion and demographic declines across the southern portion of their native distribution. A regionally representative reference genome is necessary to support conservation genomi...
A population genomic resource for Drosophila pseudoobscura [0.03%]
果蝇Drosophila pseudoobscura种群基因组资源
Yesbol Manat,Zhao Zheng,Camryn A Kritzell et al.
Yesbol Manat et al.
Drosophila pseudoobscura is an historically important organism in evolutionary genetics, serving as a model system in studies of chromosomal inversions, speciation, sex chromosome evolution, and sex-ratio drive. However, previous population...
OptOrch: A modular optimization toolkit for forest tree seed orchard deployment [0.03%]
OptOrch：用于森林树种种子园部署的模块化优化工具包
Ye-Ji Kim,Václav Bittner,Kyu-Suk Kang et al.
Ye-Ji Kim et al.
OptOrch is a transparent and modular optimization toolkit for forest tree seed orchard (SO) deployment. It implements SO-specific optimal contribution models in AMPL (A Mathematical Programming Language), separating biological assumptions, ...
A pseudo-phased genome assembly for Hemileia vastatrix reveals an isolate-specific chromosomal haploid trisomy [0.03%]
咖啡叶锈菌伪相位基因组组装揭示出一种特异于分离株的染色体单倍型三体型变异
Peri A Tobias,Richard J Edwards,Jamie Botting et al.
Peri A Tobias et al.
Recurrent epidemics of coffee leaf rust, caused by the fungal pathogen Hemileia vastatrix, have constrained production of Arabica coffee for over 150 years. Here, we present a pseudo-phased, chromosome-level genome resource for H. vastatrix...
The SOS response acts as a regulatory switch that balances helicase anti-recombination with transcription-replication conflict resolution activities in Escherichia coli [0.03%]
SOS应答作为调控开关平衡解旋酶抗重组与转录-复制冲突解纷作用的机制——兼论大肠杆菌中的动态变化
Sebastien Fleurier,Ivan Matic
Sebastien Fleurier
Transcription-replication conflicts are a major source of genome instability, particularly at highly transcribed ribosomal RNA genes, where RNA polymerase stalling can trigger replication fork collapse and double-strand breaks. We investiga...
Resampling-based evaluation of a 79-SNP panel for hybrid classification across generations: a case study in European lobster (Homarus gammarus) [0.03%]
基于重采样的评价用于杂交分类的79个SNP标记在欧洲 lobster中的世代间的适用性分析案例研究
Erik Sandertun Røed,Charlie Ellis,Jamie R Stevens et al.
Erik Sandertun Røed et al.
Accurate detection of hybridization and introgression is critical not only for basic research, but also for fisheries management. In many species, however, hybrid ancestry is difficult to detect beyond the F1 generation, especially when bas...
Sequence effects on mutation rates investigated in whole-genome sequenced UK Biobank participants [0.03%]
对整个基因组进行测序的英国生物银行受试者中序列效应影响突变率的研究
David Curtis
David Curtis
UK Biobank has released whole genome sequence data for 500,000 participants, including allele counts for hundreds of millions of variants and these were considered in the context of the pentanucleotide background on which they occurred. Var...
Paternal leakage of mitochondrial DNA is genetically controlled in Drosophila [0.03%]
果蝇线粒体DNA父本不传递由遗传因素决定
Maria-Eleni Parakatselaki,Stavroula Zapri,Sevasti Koursioti et al.
Maria-Eleni Parakatselaki et al.
Mitochondrial DNA is generally assumed to be strictly maternally inherited, with paternal leakage treated as a rare stochastic error. Using hybrids from multiple Drosophila simulans isofemale lines crossed to D. mauritiana, we assayed heter...
A Multiplex Droplet Digital PCR Assay for Chromosome Copy Number Determination in Candida albicans [0.03%]
用于白色念珠菌染色体拷贝数测定的多重液滴数字PCR检测方法
Eli Isael Maciel,Sylvain Ursuegui,Sana Ahmed-Seghir et al.
Eli Isael Maciel et al.
Chromosome copy number variation (CNV) is a major contributor to genome plasticity and adaptation in Candida albicans, a leading fungal pathogen of humans. Aneuploidy, defined as deviations from the normal diploid chromosome set, rapidly al...
Genetic variation in a plant-parasitic nematode is associated with host gene expression changes conserved across evolutionarily distant host plants [0.03%]
一种植物寄生线虫的遗传变异与宿主基因表达变化有关，这种变化在进化上距离较远的宿主植物中得到了保守
Dahlia M Nielsen
Dahlia M Nielsen
A hallmark of the interactions between endoparasites (parasites that live within plant tissue) and their hosts, is the parasites' ability to hijack host gene expression to support their own existence. While a number of studies have been per...