Whole-genome sequence of synthetically derived Brassica napus inbred cultivar Da-Ae [0.03%]
合成育种油菜甘蓝型品种Da-Ae的基因组序列
John T Davis,Ruijuan Li,Seungmo Kim et al.
John T Davis et al.
Brassica napus, a globally important oilseed crop, is an allotetraploid hybrid species with two subgenomes originating from Brassica rapa and Brassica oleracea. The presence of two highly similar subgenomes has made the assembly of a comple...
Transcriptomic analysis provides insight into the mechanism of IKKβ-mediated suppression of HPV18E6-induced cellular abnormalities [0.03%]
转录组分析提供了IKKβ介导的抑制HPV18E6诱导的细胞异常机制的见解
Quincy P Collins,Michael J Grunsted,Dahiana Arcila et al.
Quincy P Collins et al.
High-risk human papillomaviruses (HPVs) 16 and 18 are responsible for more than 70% of cervical cancers and majority of other HPV-associated cancers world-wide. Current treatments for these cancers have limited efficacy, which in turn has r...
Tyler B Smith,Daniel B Weissman
Tyler B Smith
Limited dispersal of individuals between generations results in isolation by distance, in which individuals further apart in space tend to be less related. Classic models of isolation by distance assume that dispersal distances are drawn fr...
Polycomb response elements reduce leaky expression of Cas9 under temperature-inducible Hsp70Bb promoter in Drosophila melanogaster [0.03%]
ploycomb反应元件可以降低Drosophila melanogaster中Hsp70Bb启动子驱动的Cas9表达的渗漏现象
Natalie Warsinger-Pepe,Carly Chang,Connor R Desroberts et al.
Natalie Warsinger-Pepe et al.
Heat-shock-inducible expression of genes through the use of heat-inducible promoters is commonly used in research despite leaky expression of downstream genes of interest without targeted induction (i.e. heat shock). The development of non-...
Results from rapid-cycle recurrent genomic selection in spring bread wheat [0.03%]
春小麦常规选择中基于轮回群体的基因组选择效果评估
Susanne Dreisigacker,Paulino Pérez-Rodríguez,Leonardo Crespo-Herrera et al.
Susanne Dreisigacker et al.
Genomic selection (GS) in wheat breeding programs is of great interest for predicting the genotypic values of individuals, where both additive and nonadditive effects determine the final breeding value of lines. While several simulation stu...
The effect of Drosophila attP40 background on the glomerular organization of Or47b olfactory receptor neurons [0.03%]
果蝇attP40背景对Or47b嗅觉受体神经元的球状组织的影响
Qichen Duan,Rachel Estrella,Allison Carson et al.
Qichen Duan et al.
Bacteriophage integrase-directed insertion of transgenic constructs into specific genomic loci has been widely used by Drosophila community. The attP40 landing site located on the second chromosome gained popularity because of its high indu...
Altered phenotypes due to genetic interaction between the mouse phosphoinositide biosynthesis genes Fig4 and Pip4k2c [0.03%]
Fig4和Pip4k2c鼠磷脂酰肌醇生物合成基因之间的遗传相互作用导致的改变表型
Xu Cao,Guy M Lenk,Miriam H Meisler
Xu Cao
Loss-of-function mutations of FIG4 are responsible for neurological disorders in human and mouse that result from reduced abundance of the signaling lipid PI(3,5)P2. In contrast, loss-of-function mutations of the phosphoinositide kinase PIP...
A reference genome for Bluegill (Centrarchidae: Lepomis macrochirus) [0.03%]
蓝鳃鱼(丽鱼科:Lepomis macrochirus)的参考基因组
William B Ludt,Eamon C Corbett,Jerry Kattawar et al.
William B Ludt et al.
North American sunfishes (Family Centrarchidae) are among the most popular sportfish throughout the United States and Canada. Despite the popularity of sunfishes, their ecological importance, and their extensive stocking and aquacultural hi...
Population genetic analysis of the microsporidium Ordospora colligata reveals the role of natural selection and phylogeography on its extremely compact and reduced genome [0.03%]
微孢子虫Ordospora colligata的人口遗传分析揭示了自然选择和系统地理学在其极其紧凑和简化的基因组中的作用
Pascal Angst,Dieter Ebert,Peter D Fields
Pascal Angst
The determinants of variation in a species' genome-wide nucleotide diversity include historical, environmental, and stochastic aspects. This diversity can inform us about the species' past and present evolutionary dynamics. In parasites, th...