Genome-wide screen identifies host loci that modulate Mycobacterium tuberculosis fitness in immunodivergent mice [0.03%]
全基因组筛选鉴定出可调节免疫多样性小鼠中结核杆菌适应性的宿主基因位点
Rachel K Meade,Jarukit E Long,Adrian Jinich et al.
Rachel K Meade et al.
Genetic differences among mammalian hosts and among strains of Mycobacterium tuberculosis (Mtb) are well-established determinants of tuberculosis (TB) patient outcomes. The advent of recombinant inbred mouse panels and next-generation trans...
Complete genome of the toxic mold Aspergillus pseudotamarii isolate NRRL 25517 reveals genomic instability of the aflatoxin biosynthesis cluster [0.03%]
阿夫托毒素生物合成基因簇不稳定性的产毒霉菌伪橘青霉完整基因组解析
Andrew W Legan,Brian M Mack,Hillary L Mehl et al.
Andrew W Legan et al.
Fungi can synthesize a broad array of secondary metabolite chemicals. The genes underpinning their biosynthesis are typically arranged in tightly linked clusters in the genome. For example, ∼25 genes responsible for the biosynthesis of car...
Genome assemblies of the simultaneously hermaphroditic flatworms Macrostomum cliftonense and Macrostomum hystrix [0.03%]
同时性别的两种扁平 worms(Macrostomum cliftonense和Macrostomum hystrix)的基因组组装结果
R Axel W Wiberg,Jeremias N Brand,Gudrun Viktorin et al.
R Axel W Wiberg et al.
The free-living, simultaneously hermaphroditic flatworms of the genus Macrostomum are increasingly used as model systems in various contexts. In particular, Macrostomum lignano, the only species of this group with a published genome assembl...
Characteristics of the spiny dogfish (Squalus acanthias) nuclear genome [0.03%]
棘鳍睡鲨（Squalus acanthias）基因组的特征分析
C Isabel Wagner,Martina E L Kopp,James Thorburn et al.
C Isabel Wagner et al.
Sequenced shark nuclear genomes are underrepresented, with reference genomes available for only four out of nine orders so far. Here, we present the nuclear genome, with annotations, of the spiny dogfish (Squalus acanthias), a shark of inte...
Identification of grapevine clones via high-throughput amplicon sequencing: a proof-of-concept study [0.03%]
基于高通量靶序列扩增子测序的葡萄无性系鉴定研究
Claudio Urra,Dayan Sanhueza,Catalina Pavez et al.
Claudio Urra et al.
Wine cultivars are available to growers in multiple clonal selections with agronomic and enological differences. Phenotypic differences between clones originated from somatic mutations that accrued over thousands of asexual propagation cycl...
New mutant alleles for Spargel/dPGC-1 highlights the function of Spargel RRM domain in oogenesis and expands the role of Spargel in embryogenesis and intracellular transport [0.03%]
新突变体Spargel/dPGC-1揭示了Spargel的RRM结构域在卵母细胞发生中的功能及其在胚胎发育和胞内运输中的作用
Swagota D Roy,Sabarish Nagarajan,Md Shah Jalal et al.
Swagota D Roy et al.
Energy metabolism in vertebrates is controlled by three members of the PGC-1 (PPAR γ- coactivator 1) family, transcriptional coactivators that shape responses to physiological stimuli by interacting with the nuclear receptors and other tra...
Enhancing adaptation of tropical maize to temperate environments using genomic selection [0.03%]
利用全基因组选择改进热带玉米在温带地区的适应性
Nicole E Choquette,Teclemariam Weldekidan,Jason Brewer et al.
Nicole E Choquette et al.
Tropical maize can be used to diversify the genetic base of temperate germplasm and help create climate-adapted cultivars. However, tropical maize is unadapted to temperate environments, in which sensitivities to long photoperiods and coole...
A chromosome scale assembly of the parasitoid wasp Venturia canescens provides insight into the process of virus domestication [0.03%]
灰黄蚜小蜂染色体规模基因组草图：揭示病毒 Domestication 进化过程的模式生物
Meng Mao,Tyler J Simmonds,Corinne M Stouthamer et al.
Meng Mao et al.
The parasitoid wasp Venturia canescens is an important biological control agent of stored products moth pests and serves as a model to study the function and evolution of domesticated endogenous viruses (DEVs). The DEVs discovered in V. can...
Inferring the distributions of fitness effects and proportions of strongly deleterious mutations [0.03%]
推断强有害突变的效应和比例分布
Anders P Charmouh,Greta Bocedi,Matthew Hartfield
Anders P Charmouh
The distribution of fitness effects is a key property in evolutionary genetics as it has implications for several evolutionary phenomena including the evolution of sex and mating systems, the rate of adaptive evolution, and the prevalence o...
Clonal reproduction of Moniliophthora roreri and the emergence of unique lineages with distinct genomes during range expansion [0.03%]
蒙比利奥赫里罗氏菌的无性繁殖及其在扩散过程中出现的独特谱系及不同基因组特征
Andrea Minio,Rosa Figueroa-Balderas,Stephen P Cohen et al.
Andrea Minio et al.
The basidiomycete Moniliophthora roreri causes frosty pod rot of cacao (Theobroma cacao) in the western hemisphere. Moniliophthora roreri is considered asexual and haploid throughout its hemibiotrophic life cycle. To understand the processe...