Forward genetics identifies cuticle and regulatory genes underlying cellular boundary integrity in C. elegans [0.03%]
Uroš Radović,Marcus Henricsson,Jan Borén et al.
Uroš Radović et al.
In C. elegans, the epidermis and its overlying extracellular matrix form a primary protective barrier, functioning as the first line of defense against environmental factors. To properly develop those cellular boundaries, a tightly controll...
Private QTLs and the Genetic Architecture of Hierarchical Size Traits: From Body Size to Sex-Specific Plasticity [0.03%]
Isabelle Vea,Carlos Molina,Austin S Wilcox et al.
Isabelle Vea et al.
Sex-specific size plasticity (SSP) is the phenomenon whereby the size of one sex is more environmentally sensitive than the other, and is thought to underlie the developmental regulation and evolution of sexual size dimorphism (SSD). Sex-sp...
A mdg4 Retrotransposon Screen for X-linked Female Sterile Alleles and its Relationship with the Transcription Factor OVO [0.03%]
Leif Benner,Brian Oliver
Leif Benner
In the germline, the mdg4 retrotransposon integrates in close proximity to the location of OVO DNA binding motifs, suggesting that insertion bias is driven by the OVO transcription factor. A classical genetic example of this is the reversio...
Non-uniform chromosomal SNP density biases sites of meiotic crossovers in Drosophila melanogaster [0.03%]
Savanna Hinson,Ryan Sangston,Karol Cichewicz et al.
Savanna Hinson et al.
Here we localize a genetic suppressor that enhances the reduced locomotor activity phenotype of flies lacking brain dopamine. We utilized a bulk segregant analysis (BSA) mapping strategy coupled with whole genome sequencing (WGS), mapping t...
Gene regulation in response to host sex and infection route in Brugia pahangi with new genome annotation [0.03%]
Christopher I Holt,Robin E Bromley,Benjamin C Sparklin et al.
Christopher I Holt et al.
Male rodents are almost exclusively used for experimental maintenance of filarial nematodes because they have higher susceptibility to parasitism than female rodents. This study investigates the effects that rodent host sex has on the worm ...
Genomic Insights into Antagonistic Coevolution: Collagen-Like Protein Expansion and Genome Plasticity in the Daphnia Parasite Pasteuria ramosa [0.03%]
基因组视角下的敌对协同进化：水蚤寄生虫Pasteuria ramosa胶原蛋白类似物的扩张及基因组不稳定性
Alix Thivolle,Marjut Paljakka,Dieter Ebert et al.
Alix Thivolle et al.
Collagen-like proteins (CLP) serve many pathogenic bacteria as adhesins to attach to host tissue. It was suggested that CLPs are a major determinant in the coevolution of the model system Daphnia (Crustacean) and its virulent pathogen Paste...
SIN-3 coregulator maintains adaptive capacity to different diets in Caehnorhabditis elegans through vitamin B12 [0.03%]
维生素B12通过调节适应不同饮食的表观遗传记忆来维持秀丽隐杆线虫中的环境适应性
Francesca Palladino,Cécile Bedet
Francesca Palladino
Diet has profound effects on metabolism and health, requiring animals to adapt their physiology to varying food sources. Here we show that the conserved SIN3 transcriptional coregulator is required in Caehnorhabditis elegans for animals to ...
Linked genetic loci and genotype-dependent temperature effects shape craniofacial morphology in medaka [0.03%]
连锁遗传位点和基因型依赖的温度效应塑造medaka颅面形态
Minori Shinya,Tetsuaki Kimura,Takafumi Ikeda et al.
Minori Shinya et al.
Craniofacial morphology is a fundamental and complex trait, vital for survival and crucial for social interactions such as individual recognition and mate selection. While its overall form is conserved within a species, significant individu...
Genetic Dissection of Protein Content in Cowpea Using Custom-made NIRS equations and GWAS as a Model for Nutritional Breeding and Undergraduate Research Training [0.03%]
利用近红外光谱方程和全基因组关联分析进行遗传改良以增加牛芸豆中的蛋白质含量作为营养育种及大学生研究训练的模型
Habib Akinmade,Shiri Ben-Israel,Audrey Ryan et al.
Habib Akinmade et al.
As the demand for plant-based nutrition increases, improving the protein profile of legumes like cowpea has become a breeding priority. Cowpea, a multi-use legume and staple in many low-income regions, provides important dietary protein tha...
Genes shielded, repeats exposed: mutation bias in the midge Chironomus riparius [0.03%]
基因被保护，重复序列被揭露——旋蚊科动物Chironomus riparius的突变偏向性
María Esther Nieto-Blázquez,Markus Pfenninger
María Esther Nieto-Blázquez
Mutation is the fundamental source of genetic variation, yet growing evidence shows that mutations are not uniformly distributed across genomes but are shaped by genomic architecture, DNA-repair dynamics, and environmental conditions. Here,...