Sai Zhou,Geonho Park,Katherine Longardner et al.
Sai Zhou et al.
Options for the continuous and non-invasive monitoring of blood pressure are limited. Cuff-based sphygmomanometers are widely available, yet provide only discrete measurements. The clinical gold-standard approach for the continuous monitori...
Filipe V Almeida
Filipe V Almeida
Ablation of FAS confers allogeneic CD3- CAR T cells with resistance to rejection by T cells and natural killer cells [0.03%]
FAS的敲除使CD3-CAR T细胞免受T细胞和自然杀伤细胞的排斥作用
Silvia Menegatti,Sheila Lopez-Cobo,Aurelien Sutra Del Galy et al.
Silvia Menegatti et al.
Allogeneic chimaeric antigen receptor T cells (allo-CAR T cells) derived from healthy donors could provide rapid access to standardized and affordable batches of therapeutic cells if their rejection by the host's immune system is avoided. H...
Jennifer Haskell
Jennifer Haskell
Setting morphogen gradients [0.03%]
设置形态发生素梯度
Valeria Caprettini
Valeria Caprettini
Dyeing mice transparent [0.03%]
把老鼠染透明试验
Alessandra Griffo
Alessandra Griffo
Pep Pàmies
Pep Pàmies
Endocisternal interfaces for minimally invasive neural stimulation and recording of the brain and spinal cord [0.03%]
微创大脑和脊髓神经刺激和记录的内吞体内接口技术
Joshua C Chen,Abdeali Dhuliyawalla,Robert Garcia et al.
Joshua C Chen et al.
Minimally invasive neural interfaces can be used to diagnose, manage and treat many disorders, with reduced risks of surgical complications. However, endovascular probes lack access to key cortical, subcortical and spinal targets, and are n...
Saehyuck Oh,Janghwan Jekal,Jinyoung Won et al.
Saehyuck Oh et al.
By monitoring brain neural signals, neural recorders allow for the study of neurological mechanisms underlying specific behavioural and cognitive states. However, the large brain volumes of non-human primates and their extensive range of un...
Large DNA deletions occur during DNA repair at 20-fold lower frequency for base editors and prime editors than for Cas9 nucleases [0.03%]
与Cas9核酸酶相比，碱基编辑器和prime编辑器在DNA修复过程中发生的大型DNA缺失频率低20倍
Gue-Ho Hwang,Seok-Hoon Lee,Minsik Oh et al.
Gue-Ho Hwang et al.
When used to edit genomes, Cas9 nucleases produce targeted double-strand breaks in DNA. Subsequent DNA-repair pathways can induce large genomic deletions (larger than 100 bp), which constrains the applicability of genome editing. Here we sh...