Efficient assembly of 1-(1H-imidazol-1-yl)-3-methylene-1H-indenes via tandem reaction of (2-(alkynyl)benzylidene)malonates with imidazoles [0.03%]
通过(2-(烷基炔基)苯基亚甲基)丙二酸酯与咪唑的串联反应高效合成1-(1H-咪唑-1-基)-3-亚甲基-1H-茚类化合物
Guanyinsheng Qiu,Qiuping Ding,Ke Gao et al.
Guanyinsheng Qiu et al.
The tandem nucleophilic addition and 5-exo-cyclization of (2-(alkynyl)benzylidene)malonates with imidazole derivatives in the presence of t-BuOK is reported. This reaction proceeds smoothly under mild conditions with high selectivity to aff...
Silica-supported aluminum chloride-assisted solution phase synthesis of pyridazinone-based antiplatelet agents [0.03%]
介孔 silica 质子受体辅助的抗血小板药物吡啶并咪唑酮的溶液相合成法研究
Abdelaziz El Maatougui,Jhonny Azuaje,Eddy Sotelo et al.
Abdelaziz El Maatougui et al.
A solution phase protocol that enabled the synthesis of three diverse libraries of pyridazin-3-ones incorporating α,β-unsaturated moieties at position 5 of the heterocyclic core has been developed using silica-supported aluminum trichlori...
Open vessel and cooling while heating microwave-assisted synthesis of pyridinyl N-aryl hydrazones [0.03%]
开放式容器微波加热制备吡啶基N-芳肼类化合物
Giuseppe La Regina,Valerio Gatti,Francesco Piscitelli et al.
Giuseppe La Regina et al.
We reported the first example of open vessel and cooling while heating microwave-assisted synthesis of pyridinyl N-aryl hydrazones. Compounds were prepared in excellent isolated yields (88-98%) in only 5 min, by reacting 4- and 2,4-(di)subs...
M G Finn
M G Finn
Multicomponent synthesis of poly-substituted benzo[a]pyrano[2,3-c]phenazine derivatives under microwave heating [0.03%]
微波加热下多组分合成多取代苯并[a]吡喃并[2,3-c]菲挫类化合物
Shu-Liang Wang,Fei-Yue Wu,Chuang Cheng et al.
Shu-Liang Wang et al.
A new one-pot two-step tandem synthesis of highly functionalized benzo[a]pyrano[2,3-c]phenazine derivatives via microwave-assisted multicomponent reactions of 2-hydroxynaphthalene-1,4-dione, diamines, aldehydes, and malononitrile is reporte...
Combinatorial synthesis of mixed transition metal oxides for lithium-ion batteries [0.03%]
用于锂离子电池的混合过渡金属氧化物的组合合成
Graham H Carey,J R Dahn
Graham H Carey
Many methods exist for the synthesis of lithium metal oxides for use as positive electrode materials in lithium-ion batteries; however, no such method to date is both combinatorial (able to process broad ranges of compositional space quickl...
Combinatorial synthesis of 3-arylideneaminoquinazolin-4(1H)-one derivatives catalyzed by iodine in ionic liquids [0.03%]
碘催化离子液体中3-芳亚氨基喹唑啉-4-(1H)-酮衍生物的组合合成法研究
Xiang-Shan Wang,Jie Sheng,Lian Lu et al.
Xiang-Shan Wang et al.
A combinatorial synthesis of 3-arylideneaminoquinazolin-4(1H)-one derivatives is described by a reaction of 2-aminobenzohydrazides with two equivalents of aldehydes or ketones in ionic liquids catalyzed by iodine. Controlling the reaction t...
Improved small-molecule macroarray platform for the rapid synthesis and discovery of antibacterial chalcones [0.03%]
改进的小分子宏阵列平台，用于抗菌查尔康素的快速合成与发现
Joseph R Stringer,Matthew D Bowman,Bernard Weisblum et al.
Joseph R Stringer et al.
Bacterial resistance to current antibiotics is a major global health threat. Consequently, there is an urgent need for the identification of new antibacterial agents. We are applying the small-molecule macroarray platform to rapidly synthes...
Genetic algorithm-assisted optimization of nanoporous TiO₂ for low-temperature processable photoanodes of dye-sensitized solar cells [0.03%]
基于遗传算法优化纳米多孔TiO₂作为低能耗染料敏化太阳能电池光阳极的研究
Soyoung Kim,Kee-Sun Sohn,Myoungho Pyo
Soyoung Kim
Genetic algorithm (GA), a promising optimization process in Heuristics, has proven to be a powerful tool in controlling the nanostructure of low-temperature processable photoanodes in dye-sensitized solar cells (DSSC). For photoanodes that ...