Efficient assembly of 1-(1H-imidazol-1-yl)-3-methylene-1H-indenes via tandem reaction of (2-(alkynyl)benzylidene)malonates with imidazoles
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The tandem nucleophilic addition and 5-exo-cyclization of (2-(alkynyl)benzylidene)malonates with imidazole derivatives in the presence of t-BuOK is reported. This reaction proceeds smoothly under mild conditions with high selectivity to afford the correspondin... ...
