Effect of out of plane orientation on polarization second harmonic generation of single collagen fibrils [0.03%]
单胶原纤维极化二次谐波产生的平面外取向影响效应
MacAulay Harvey,Richard Cisek,Danielle Tokarz et al.
MacAulay Harvey et al.
Second harmonic generation (SHG) microscopy has emerged as a powerful technique for visualizing collagen organization within tissues. Amongst the many advantages of SHG is its sensitivity to collagen nanoscale organization, and its presumed...
828 kHz retinal imaging with an 840 nm Fourier domain mode locked laser [0.03%]
使用840nm傅里叶域锁模激光进行828kHz视网膜成像
Marie Klufts,Alejandro Martínez Jiménez,Simon Lotz et al.
Marie Klufts et al.
This paper presents a Fourier domain mode locked (FDML) laser centered around 840 nm. It features a bidirectional sweep repetition rate of 828 kHz and a spectral bandwidth of 40 nm. An axial resolution of ∼9.9 µm in water and a 1.4 cm sen...
Potential vision tester using adaptive optics, Maxwellian view, and small pupil [0.03%]
一种使用自适应光学，麦克斯韦视角和小瞳孔的潜在视力检测器
Ann E Elsner,Joel A Papay,Vamsi Parimi et al.
Ann E Elsner et al.
We demonstrate a free-space, trolley-mounted potential vision tester (PVT), designed to study and improve the accuracy of visual acuity (VA) measurements in the aging eye. Key features include a high-resolution visual display presented in M...
Wearable optical coherence tomography angiography probe for freely moving mice [0.03%]
用于自由活动小鼠的可穿戴光学相干断层扫描血管成像探头
Xiangyu Guo,Xiaochen Li,Xinyue Wang et al.
Xiangyu Guo et al.
Optical coherence tomography (OCT) is an emerging optical imaging technology that holds great potential in medical and biological applications. Apart from its conventional ophthalmic uses, it has found extensive applications in studying var...
Speckle contrast reduction through the use of a modally-specific photonic lantern for optical coherence tomography [0.03%]
通过使用模态特异性光子灯减少光学相干断层扫描中的斑点对比度
Raphaël Maltais-Tariant,Rodrigo Itzamna Becerra-Deana,Simon Brais-Brunet et al.
Raphaël Maltais-Tariant et al.
A few-mode optical coherence tomography (FM-OCT) system was developed around a 2 × 1 modally-specific photonic lantern (MSPL) centered at 1310 nm. The MSPL allowed FM-OCT to acquire two coregistered images with uncorrelated speckle pattern...
Optimal calibration of optical tweezers with arbitrary integration time and sampling frequencies: a general framework [Invited] [0.03%]
具有任意积分时间和采样频率的光学陷阱的最佳校准：通用框架[特邀]
Laura Pérez-García,Martin Selin,Antonio Ciarlo et al.
Laura Pérez-García et al.
Optical tweezers (OT) have become an essential technique in several fields of physics, chemistry, and biology as precise micromanipulation tools and microscopic force transducers. Quantitative measurements require the accurate calibration o...
Miniaturized, high numerical aperture confocal fluorescence detection enhanced with pyroelectric droplet accumulation for sub-attomole analyte diagnosis [0.03%]
结合焦热电积液技术和亚飞摩尔检测的微型化高数值孔径共聚焦荧光检测系统
Yunfeng Nie,Uusitalo Sanna,Teemu Sipola et al.
Yunfeng Nie et al.
To meet the growing demand for early fatal disease screening among large populations, current fluorescence detection instruments aiming at point-of-care diagnosis have the tendency to be low cost and high sensitivity, with a high potential ...
Capturing the pulse: a state-of-the-art review on camera-based jugular vein assessment [0.03%]
捕捉脉搏跳动：关于基于相机的颈静脉评估的最新综述
Coen Arrow,Max Ward,Jason Eshraghian et al.
Coen Arrow et al.
Heart failure is associated with a rehospitalisation rate of up to 50% within six months. Elevated central venous pressure may serve as an early warning sign. While invasive procedures are used to measure central venous pressure for guiding...
3D imaging of aqueous veins and surrounding sclera using a dual-wavelength photoacoustic microscopy [0.03%]
使用双波长光声显微镜对水静脉及其周围巩膜进行三维成像
Linyu Ni,Wei Zhang,Wonsuk Kim et al.
Linyu Ni et al.
Understanding aqueous outflow resistance at the level of aqueous veins has been a challenge to the management of glaucoma. This study investigated resolving the anatomies of aqueous veins and the textures of surrounding sclera using photoac...
Real-time OCT feedback-controlled RPE photodisruption in ex vivo porcine eyes using 8 microsecond laser pulses [0.03%]
使用8微秒激光脉冲对离体猪眼进行实时OCT反馈控制的RPE光中断
Christian Burri,Simon Salzmann,Jasmin Wandel et al.
Christian Burri et al.
Selective retinal pigment epithelium (RPE) photodisruption requires reliable real-time feedback dosimetry (RFD) to prevent unwanted overexposure. In this study, optical coherence tomography (OCT) based RFD was investigated in ex vivo porcin...