Sub-50-femtosecond gain-managed amplified pulses enhance nonlinear ablation efficiency [0.03%]
亚50飞秒增益管理放大脉冲可提高非线性消融效率
Liam J Price,Kai Zhang,Nicholas J Otero et al.
Liam J Price et al.
Nonlinear femtosecond (fs) laser ablation enables highly localized energy deposition for cell microsurgery. Conventional systems operate at either low (∼1 kHz, amplified µJ pulse energy) or high (∼80 MHz, unamplified low nJ) repetition r...
Erratum: Imaging otoconia by second harmonic generation microscopy: erratum [0.03%]
Correction：双光子显微镜成像技术用于拍摄耳石器官中的卵磷脂丛杂蛋白(otogelin)和碳酸钙晶体(otoconia)
Kennedy Brittain,MacAulay Harvey,Richard Cisek et al.
Kennedy Brittain et al.
[This corrects the article on p. 3593 in vol. 13, PMID: 35781949.]. © 2025 Optica Publishing Group.
Published Erratum
Biomedical optics express. 2025 Dec 24;17(1):511. DOI:10.1364/BOE.587992 2025
Hybrid particle-wave Monte Carlo OCT simulation method provides a three orders of magnitude improvement in efficiency [0.03%]
混合粒子-波蒙特卡洛OCT模拟方法提供了三阶效率改进
Gijs Buist,Arjen Amelink,Johannes F de Boer
Gijs Buist
The attenuation coefficient of biological tissue could serve as an indicator of structural and functional changes related to the onset or progression of disease. Optical coherence tomography (OCT) provides cross-sectional images of tissue u...
Deep ultraviolet ultrashort laser pulses for precise ablation of soft biological tissue [0.03%]
深紫外超短激光脉冲实现软组织精确消融
Tatiana K Malikova,Rainer J Beck,Timothy P Frazer et al.
Tatiana K Malikova et al.
Laser ablation offers the potential for precisely removing pathological tissue without damaging surrounding healthy structures. Among the existing laser types, deep ultraviolet ultrashort pulsed lasers offer the highest axial precision and ...
Translational photoacoustic and ultrasound imaging catheter for characterizing gastrointestinal inflammation and fibrosis: a study with a pig model in vivo [0.03%]
一种用于表征胃肠炎症和纤维化的透译式光声和超声成像导管：体内猪模型研究
Yaocai Huang,Laura A Johnson,Xiaorui Peng et al.
Yaocai Huang et al.
Our previous studies demonstrated that a prototype photoacoustic (PA) and ultrasound (US) imaging catheter can differentiate intestinal inflammation and fibrosis. However, its compatibility with clinical endoscopic procedures has not been v...
Diffusion prior-based zero-shot denoising for real-world fluorescence microscopy images via encoder-decoder guided sampling [0.03%]
基于编码器-解码器引导采样的真实世界荧光显微图像零样本去噪扩散先验方法
Qinxuan Luo,Ziwen Liu,Ge Yang
Qinxuan Luo
Fluorescence microscopy is an important imaging technique for biological research and applications. However, owing to various constraints in its engineering implementation and image acquisition, the acquired images often suffer from substan...
Investigating neurovascular responses of the peripapillary retinal artery to focal flicker stimulation of temporal retinal neurons in the living human eye using AO-OCT [0.03%]
利用AO-OCT研究活体人眼中视网膜颞侧神经元焦点闪烁刺激引起的周边视盘 retina 动脉的神经血管反应
Arwa Arrashoud,Morgan Nemeth,Kazuhiro Kurokawa
Arwa Arrashoud
We have developed an AO-OCT-based method to characterize microscopic vasodilatory responses of peripapillary major retinal artery (ppRA) to the focal luminous flicker stimulation of peripheral retinal neurons (>15° temporal to the fovea) w...
Fully 3D-printed endomicroscopic objective for two-photon, multi-wavelength excitation microscopy [0.03%]
用于两光子、多波长激发显微镜的全3D打印内窥镜物镜
Jinyun Liu,Roy Lycke,Lan Luan et al.
Jinyun Liu et al.
We present a fully 3D-printed, broadband endomicroscopic objective optimized for near-infrared two-photon fluorescence imaging, featuring a compact, alignment-free design. The objective provides a numerical aperture of 0.6 in water immersio...
Wojciech Krauze,Martyna Mazur,Arkadiusz Kuś et al.
Wojciech Krauze et al.
Transmission optical coherence tomography (OCT) enables analysis of biological specimens in vitro through the detection of forward-scattered light. Up to now, transmission OCT has been considered a technique that cannot directly retrieve qu...
Terahertz attenuated total reflection imaging of fresh brain glioma based on a solid immersion lens [0.03%]
基于固态浸没物镜的太赫兹衰减全反射新鲜脑胶质瘤成像
Haibin Li,Yuye Wang,Zelong Wang et al.
Haibin Li et al.
The diagnosis and treatment of gliomas depend greatly on the precise delineation of tumor boundaries and the rapid extraction of molecular pathological features. The development of high-resolution and high-sensitivity terahertz (THz) attenu...