Hoda Lotfipour,Hassan Sobhani,Mohamad Taghi Dejpasand et al.
Hoda Lotfipour et al.
Application of quantum imaging in biology In biology, one of the main challenges is achieving a balance between high precision and minimal invasiveness in measurements. With cutting-edge techniques, the primary limitations to experimental a...
Axicons for improved resolution and depth of focus in adaptive optics scanning light ophthalmoscopy [0.03%]
用于自适应光学扫描激光眼底断层扫描的 axicon 提高分辨率和景深
Ruth E Woehlke,Robert F Cooper
Ruth E Woehlke
Adaptive optics scanning light ophthalmoscopes are instrumental for studying the eye, yet they use truncated Gaussian illumination and are limited by diffraction, restricting resolution and depth of focus (DOF). Non-diffractive Bessel beams...
Ultra-fast line-field swept source scanning optical coherence elastography [0.03%]
超快线场扫源扫描光学相干弹性断层成像技术
Cheng Lu,Jianli Ren,Xikai Wei et al.
Cheng Lu et al.
The drawbacks of repeated excitations and long imaging time in wave-based optical coherence elastography limited its application in ophthalmology. In this study, we put forward a swept source scanning optical coherence elastography (SSS-OCE...
Wide-field quantitative micro-elastography of freshly excised human prostate [0.03%]
新鲜切除的人类前列腺的宽场量化微弹性图谱
Szymon Tamborski,Marta K Skrok,Matt S Hepburn et al.
Szymon Tamborski et al.
Prostate cancer is a significant global health issue. To advance diagnostic and treatment procedures, such as image-guided needle biopsy, optical imaging methods offering high spatial resolution have been proposed. Optical coherence tomogra...
Experimental and numerical investigation of wavelength and resolution dependency of dynamic optical coherence tomography signals [0.03%]
动态光学相干层析信号的波长和分辨率依赖性的实验和数值研究
Shumpei Fujimura,Ibrahim Abd El-Sadek,Rion Morishita et al.
Shumpei Fujimura et al.
The wavelength and system-resolution dependencies of dynamic optical coherence tomography (DOCT) are investigated experimentally and numerically. Experimental investigations demonstrate significant wavelength dependency for the DOCT values ...
David A Atchison,W N Charman,Matt Jaskulski
David A Atchison
We used modeling to investigate the imaging characteristics of two multi-segment spectacle lenses intended to treat myopia progression. Determinations were made for the peripheral field, when the eye looks through the lens center, and for f...
Enhanced supercritical angle localization microscopy through point spread function modeling [0.03%]
基于点扩散函数建模的超临界角定位显微镜技术改善方法研究
Sajjad A Khan,Keith A Lidke,Sheng Liu
Sajjad A Khan
Single-molecule localization microscopy (SMLM) enables precise spatial localization of single molecules in cellular structures. A phenomenon called supercritical angle fluorescence (SAF) is utilized in SMLM (SAF-SMLM) to estimate the axial ...
Quantifying uncertainty in phasor-based time-domain fluorescence lifetime imaging microscopy [0.03%]
基于相位的荧光寿命成像显微术的时间域不确定性量化
Qinyi Chen,Jongchan Park,Shuqi Mu et al.
Qinyi Chen et al.
The phasor approach to time-domain fluorescence lifetime imaging microscopy (FLIM) offers a powerful, fit-free method for analyzing complex fluorescence decay signals. However, its quantitative accuracy is fundamentally limited by noise-par...
ISOSNet: a unified framework for cone photoreceptor detection and inner segment and outer segment length measurement from AO-OCT B-scans [0.03%]
基于自适应光学OCT-B扫描的视网膜锥细胞检测及内外节长度测量一体化网络模型
Mengxi Zhou,Yue Zhang,Eli Kirkendall et al.
Mengxi Zhou et al.
Adaptive optics-optical coherence tomography (AO-OCT) enables cellular-level in vivo visualization of cone photoreceptors in the human retina. Cone biomarkers, such as density, inner segment (IS), and outer segment (OS) lengths, are potenti...
Scattering reduced imaging of spheroids via refractive index estimation and shift-variant deconvolution [0.03%]
基于折射率估计和变模糊核的散射衰减成像算法研究
Yoshimasa Suzuki,Shintaro Fujii,Satoshi Watanabe et al.
Yoshimasa Suzuki et al.
Confocal laser scanning microscopy (CLSM) is widely used in biological research, but imaging the deep regions of three-dimensional samples like spheroids is challenging due to scattering. We propose a computational method that estimates the...