Generalizable framework for multi-site bone density prediction using non-dominant wrist optical biomarkers [0.03%]
基于非优势腕部光学生物标志物的多中心骨密度预测通用框架
Wei-Chun Chang,Takhellambam Gautam Meitei,Yi-Min Wang et al.
Wei-Chun Chang et al.
Osteoporosis is a common skeletal disorder characterized by reduced bone mineral density (BMD) and elevated fracture risk, particularly in aging populations. This study presents a machine learning framework for intelligent optical bone dens...
Erratum: Review of dynamic optical coherence tomography for intracellular motility [Invited]: errata [0.03%]
综述：用于细胞内运动的动态光学相干层析技术[特邀]：勘误
Amy L Josefsberg,Lin Yang,Taylor N Robinson
Amy L Josefsberg
[This corrects the article on p. 5005 in vol. 16, PMID: 41394485.]. © 2026 Optica Publishing Group.
Published Erratum
Biomedical optics express. 2026 May 29;17(6):3340. DOI:10.1364/BOE.605886 2026
Digital-micromirror-device-based illumination strategies for background suppression in single-molecule localization microscopy [0.03%]
基于数字微镜器件的背景抑制定位超分辨光学显微成像照明策略研究
Jing Yao,Jiarui Zhang,Ming Xu et al.
Jing Yao et al.
Single-molecule localization microscopy (SMLM) achieves super-resolution imaging by exciting sparsely distributed fluorescent emitters and precisely localizing their positions over long acquisition sequences. However, background signals ari...
Synergistic combination of convective self-assembly and hollow core fiber for sensitive SERS detection of glucose molecules [0.03%]
对流自组装和中空芯纤维的协同组合用于葡萄糖分子表面增强拉曼检测
Hyuck Ju Kwon,Hunguk Son,Seung Ho Choi et al.
Hyuck Ju Kwon et al.
This study demonstrates a highly sensitive surface-enhanced Raman scattering (SERS) platform developed by integrating convective self-assembly (CSA) with hollow core fibers (HCFs). Traditional solid-core-based fiber-optic SERS probes, such ...
Multimodal diagnostic network integrating infrared and mass spectra for lung cancer [0.03%]
融合红外光谱和质谱的肺癌多模态诊断网络
Lianting Huang,Xiangyu Zhao,Yudong Tian et al.
Lianting Huang et al.
Lung cancer has high global morbidity and mortality, and accurate early diagnosis is critical for improving prognosis. Fine-needle aspiration (FNA) is a minimally invasive initial screening tool, but traditional analytical methods (e.g., he...
Multimodal Optical Biosensing for Precision Medicine and Healthcare: Introduction to the feature issue [0.03%]
精准医疗和保健的多模态光学生物传感：特刊介绍
Santosh Kumar,Ragini Singh,Emiliano Schena et al.
Santosh Kumar et al.
The feature issue "Multimodal Optical Biosensing for Precision Medicine and Healthcare," published in Biomedical Optics Express, is a curated selection of advances in optical biosensing technologies and their applications in healthcare and ...
Automated anatomically guided quality assessment for OCTA via multi-region analysis and statistical calibration [0.03%]
基于多区域分析和统计校准的OCTA解剖引导自动质量评估方法
Enrui Zhang,Hengyi Yuan,Lei Zhang et al.
Enrui Zhang et al.
Reliable optical coherence tomography angiography (OCTA) requires not only high-resolution acquisition but also standardized image quality control to ensure accurate vascular quantification. However, existing quality assessment approaches l...
Image stitching for probe-based confocal laser endomicroscopy via a motion consistency constraint [0.03%]
基于运动一致性的探针共聚焦激光内镜图像拼接方法研究
Zhengyi Hao,Yuyang Wan,Tingting Lu et al.
Zhengyi Hao et al.
Probe-based confocal laser endomicroscopy (pCLE) enables in vivo optical biopsy with cellular resolution, but its limited field of view makes large-area tissue inspection difficult and necessitates image stitching. Under clinically relevant...
Laser speckle imaging for biofilm viability assessment: a noninvasive alternative to the MTT assay [0.03%]
用于生物膜活性评估的激光散斑成像法：一种不破坏细胞的MTT检测替代方法
David Ivan Loaiza-Toscuento,Cruz E Perez-Corona,Teresita Spezzia-Mazzocco et al.
David Ivan Loaiza-Toscuento et al.
Accurate measurement of cell viability in biofilms is critical in biology and medicine. We propose two laser speckle-based methods to assess the viability of Candida tropicalis biofilms. Time-varying speckle images were processed using temp...
Optimization of spatial and temporal sampling resolution for optophysiology in large-scale two-photon calcium imaging [0.03%]
大规模双光子钙成像的光电生理学时空采样分辨率优化
Dian Chen,Mingxuan Wang,Patrick O Kanold et al.
Dian Chen et al.
Large-scale neural circuit analysis requires multiphoton calcium imaging systems capable of monitoring thousands of neurons, creating fundamental trade-offs between spatial coverage, temporal resolution, and data quality. While reduced samp...