Impact of the β correction factor on the accuracy of speckle contrast imaging measurements [0.03%]
β校正因子对speckle对比度成像测量准确性的影响
Nataliya Makeeva,Markus Ong,Christian Crouzet et al.
Nataliya Makeeva et al.
Laser speckle imaging (LSI) is a non-invasive technique for quantifying superficial blood flow based on speckle contrast analysis. A critical factor influencing blood flow calculations is the β coefficient, which accounts for system-specif...
Miguel Faria-Ribeiro,Noé Villemagne,Luc Joannes
Miguel Faria-Ribeiro
Accurate optical bench characterization of intraocular lenses (IOLs) under white-light conditions requires model eyes that reproduce both physiological spherical aberration (SA) and longitudinal chromatic aberration (LCA). Although current ...
NanorulerQA: quantitative quality analysis of dual-color DNA nanorulers via single-molecule photobleaching step counting and spatio-temporal colocalization [0.03%]
纳米标尺的质量分析：基于单分子光漂白计数和时空共定位的双色DNA纳米标尺定量质量评估
Jingjing Wu,Chong Li,Yaolong Li et al.
Jingjing Wu et al.
Dual-color DNA nanorulers are critical tools for characterizing the resolution of dual-color super-resolution imaging systems. However, existing quality analysis methods struggle to directly quantify the number of dye molecules (i.e., the d...
Comparative mechanical profiling of MCF-7 cells in 2D and 3D cultures via optical tweezers [0.03%]
基于光学镊子的MCF-7细胞2D和3D培养体系的力学性能比较研究
Zahra Akbarpour,Milad Malekmohammadi,Reza Taghizadeh-Tabarsi et al.
Zahra Akbarpour et al.
Breast cancer cells experience distinct mechanical forces within the 3D tumor microenvironment, and these forces strongly influence cell behavior, invasion potential, and treatment response. While conventional two-dimensional culture system...
WeakMitoSAM: competitive prompt aggregation for point-supervised mitochondria segmentation in electron microscopy images [0.03%]
弱监督电子显微镜图像线粒体分割的竞合提示点集方法
Yuanwei Li,Xinliang Zhang,Hangzhou He et al.
Yuanwei Li et al.
Mitochondrial morphology is a critical indicator of cellular metabolic status and disease pathogenesis, requiring high-resolution visualization and precise segmentation in electron microscopy (EM) images. While fully supervised deep learnin...
Chronic two-photon microscopy reveals neuronal activity patterns in the cerebral cortex of an Alzheimer's disease mouse model [0.03%]
慢性双光子显微镜揭示阿尔茨海默病小鼠模型大脑皮层神经元活动模式
Fei Chen,Meng Xue,Haipeng Wang et al.
Fei Chen et al.
Chronic two-photon microscopy is used to investigate neuronal activity patterns in the primary visual cortex of Alzheimer's disease mice (5×FAD). We find that under resting conditions, individual AD neurons exhibit hyperactivity while the ...
Multi-modal and inter-device retinal OCT registration via learning-based feature correspondence [0.03%]
基于学习的特征对应多模态和跨设备视网膜OCT配准
Tiffany Tse,Zhuoting Xie,Mohammad Shahidul Islam et al.
Tiffany Tse et al.
Accurate registration of widefield OCT volumes is essential in ophthalmology to compensate for motion artifacts, enhance image quality, and enable precise delineation of retinal structures for both single- and multi-modal imaging. We presen...
Five-modal multiphoton microscopy enabled by a tunable dual-wavelength fiber laser [0.03%]
一种可调双波长光纤激光器实现的五模态多光子显微镜
Lihao Zhang,Runzhi Chen,Xinyi Wang et al.
Lihao Zhang et al.
Coherent anti-Stokes Raman scattering (CARS) microscopy provides chemically specific, label-free contrast that complements the structural and functional information offered by multiphoton microscopy (MPM). However, the widespread adoption o...
High-speed full-field swept-source dynamic optical coherence tomography enabled by neural-network-based image generation [0.03%]
基于神经网络的图像生成驱动的高速全场扫频源光学相干层析血管造影技术
Suzuyo Komeda,Nobuhisa Tateno,Yusong Liu et al.
Suzuyo Komeda et al.
We demonstrate neural-network-based high-speed and high-definition dynamic full-field swept-source optical coherence microscopy (D-FF-SSOCM). FF-SSOCM provides high-definition OCT images, but, particularly in DOCT imaging, it results in a s...
Fluorescence spectroscopy precorrection model robust to large variability of optical properties: application to point of care quantitative liver graft viability assessment [0.03%]
一种鲁棒的荧光光谱预校正模型用于肝移植器官术前评估
Antoine Uzel,Arthur Gautheron,Olivier Lopez et al.
Antoine Uzel et al.
Optical properties correction models for fluorescence spectroscopy faced limitations due to the high variability of optical properties. Typically, the point-of-care assessment of liver graft viability remains a critical challenge in transpl...