High-power organic light-emitting diodes for photodynamic therapy in a mouse model of oral squamous cell carcinoma [0.03%]
用于口腔鳞状细胞癌小鼠模型光动力治疗的高功率有机发光二极管
Jiechen Zhang,Shun Zhi,Yunlei Xu et al.
Jiechen Zhang et al.
Effective light delivery with precise control is critical for achieving safe and efficient photodynamic therapy (PDT). Organic light-emitting diodes (OLEDs) represent an attractive novel light source for PDT due to their large-area, uniform...
Noninvasive prediction of photon fluence rate in targeted brain regions for personalized transcranial photobiomodulation dosage: model development and in silico evaluation [0.03%]
用于个性化经颅光生物调节剂量的目标脑区非侵入式预测光子通量率的模型开发与仿真评估
Yu-Chia Chang,Bo-Yong Lin,Yu-Peng Hsieh et al.
Yu-Chia Chang et al.
Transcranial photobiomodulation (tPBM) shows promise in delivering beneficial effects to the brain. However, accurately estimating the stimulus energy reaching the targeted brain region remains difficult due to individual differences in ana...
Pedro Gil,Juan Tabernero,Silvestre Manzanera et al.
Pedro Gil et al.
Human vision is considered limited to the visible range (∼400-700 nm), yet studies have shown that near-infrared light can elicit visual perception through a nonlinear process known as two-photon vision. This occurs when two infrared photo...
Mapping of blood flow and slow speckle tissue dynamics using laser speckle contrast imaging [0.03%]
基于激光散斑对比度成像的血流及组织动力学映射研究
Bingxue Liu,Rockwell P Tang,Emily A Long et al.
Bingxue Liu et al.
Laser speckle contrast imaging (LSCI) is a wide-field optical technique commonly used to monitor cerebral blood flow (CBF). Recently, we have discovered that besides the fast-decorrelating signals from blood flow, LSCI can also detect slow-...
E Russomanno,X Yang,H Zohdi et al.
E Russomanno et al.
Near-infrared spectroscopy (NIRS) is a widely used non-invasive method for measuring oxygenation and hemodynamics. NIRS devices are validated using phantoms that accurately replicate the optical properties of human tissue. The aim was to de...
Maxim N Cherkashin,Jan Laufer,Thomas Kirchner
Maxim N Cherkashin
Photoacoustic (PA) imaging of deep tissue tends to employ Q-switched lasers with high pulse energy to generate high optical fluence and therefore high PA signal. Compared to Q-switched lasers, pulsed laser diodes (PLDs) typically generate l...
Polar organization of H&E dyes in histology tissue revealed by polarimetric nonlinear microscopy [0.03%]
基于偏振非线性显微镜的组织切片苏木精和伊红染料的空间分布研究
Mykolas Maciulis,Viktoras Mazeika,Lukas Kontenis et al.
Mykolas Maciulis et al.
Structural organization of harmonophores used in hematoxylin (H) and eosin (E) staining is studied with polarimetric multimodal second-harmonic generation (SHG), third-harmonic generation (THG), and multiphoton excitation fluorescence (MPF)...
Label-free visualization and quantitative analysis of Far UV-C skin safety with dynamic optical coherence tomography with subcellular resolution [0.03%]
无标签可视化和定量分析远紫外线皮肤安全性及亚细胞分辨率动态光学相干层析技术
Felix Hilge,Michael Wang-Evers,Lara Buhl et al.
Felix Hilge et al.
The recent COVID-19 pandemic sparked interest in interventional public health measures like ultraviolet germicidal irradiation (UVGI) of occupied spaces with the development of Far UV-C (200-230 nm) emitting sources promising similar antimi...
Quantification of oxidized and reduced cytochrome-c-oxidase by combining discrete-wavelength time-resolved and broadband continuous-wave near-infrared spectroscopy [0.03%]
结合离散波长瞬态和宽带连续近红外光谱定量细胞色素-c-氧化酶的氧化和还原形式
Rasa Eskandari,Natalie C Li,Saeed Samaei et al.
Rasa Eskandari et al.
Quantification of cytochrome-c-oxidase (CCO) can directly inform about cerebral metabolic capacity and function, but limited options currently exist for its in vivo assessment. Near-infrared spectroscopy (NIRS) has the potential to quantify...
Ultrahigh-resolution spectral domain optical coherence tomography with a blue-diode-pumped Ti:sapphire laser and an axicon lens [0.03%]
蓝光Ti:Sapphire激光器及轴锥透镜的超广谱域光学相干层析成像技术
Manuel Zeyen,Karlo Lajtner,Gregory Zaugg et al.
Manuel Zeyen et al.
We present a novel, low-cost ultrahigh-resolution optical coherence tomography (OCT) system, based on a broadband blue-diode-pumped Kerr-lens mode-locked Ti:sapphire laser and an axicon lens to achieve high axial and lateral resolutions, re...