Automated anatomically guided quality assessment for OCTA via multi-region analysis and statistical calibration [0.03%]
基于多区域分析和统计校准的OCTA解剖引导自动质量评估方法
Enrui Zhang,Hengyi Yuan,Lei Zhang et al.
Enrui Zhang et al.
Reliable optical coherence tomography angiography (OCTA) requires not only high-resolution acquisition but also standardized image quality control to ensure accurate vascular quantification. However, existing quality assessment approaches l...
Image stitching for probe-based confocal laser endomicroscopy via a motion consistency constraint [0.03%]
基于运动一致性的探针共聚焦激光内镜图像拼接方法研究
Zhengyi Hao,Yuyang Wan,Tingting Lu et al.
Zhengyi Hao et al.
Probe-based confocal laser endomicroscopy (pCLE) enables in vivo optical biopsy with cellular resolution, but its limited field of view makes large-area tissue inspection difficult and necessitates image stitching. Under clinically relevant...
Laser speckle imaging for biofilm viability assessment: a noninvasive alternative to the MTT assay [0.03%]
用于生物膜活性评估的激光散斑成像法：一种不破坏细胞的MTT检测替代方法
David Ivan Loaiza-Toscuento,Cruz E Perez-Corona,Teresita Spezzia-Mazzocco et al.
David Ivan Loaiza-Toscuento et al.
Accurate measurement of cell viability in biofilms is critical in biology and medicine. We propose two laser speckle-based methods to assess the viability of Candida tropicalis biofilms. Time-varying speckle images were processed using temp...
Optimization of spatial and temporal sampling resolution for optophysiology in large-scale two-photon calcium imaging [0.03%]
大规模双光子钙成像的光电生理学时空采样分辨率优化
Dian Chen,Mingxuan Wang,Patrick O Kanold et al.
Dian Chen et al.
Large-scale neural circuit analysis requires multiphoton calcium imaging systems capable of monitoring thousands of neurons, creating fundamental trade-offs between spatial coverage, temporal resolution, and data quality. While reduced samp...
Spatially resolved in vivo ratiometric imaging of mitochondrial quality control using co-registered confocal-OCT [0.03%]
基于共聚焦-OCT的线粒体质量控制活体比率成像的时空分辨研究
Amit Hasan Sadhin,Janani Rajasekar,Taeyoon Son et al.
Amit Hasan Sadhin et al.
Mitochondrial quality control is essential for maintaining cellular bioenergetic homeostasis, but in vivo monitoring of its spatial dynamics remains difficult to quantify. Here we present a multimodal retinal imaging approach that enables s...
Multiparametric dynamic optical coherence tomography for evaluation of human cardiac organoids subjected to external stress [0.03%]
用于评估受外力作用的人类心脏器官的多参数动态光学相干层析成像技术
Nchumpeni Chonpemo Shitiri,Thanh Dat Le,Soo Ji Yoo et al.
Nchumpeni Chonpemo Shitiri et al.
Understanding how cardiac organoids respond to environmental stress is essential for advancing cardiac research and drug screening. In this study, we introduce a multiparametric dynamic optical coherence tomography (MP-DOCT) to characterize...
NIR autofluorescence allows for pituitary gland detection during surgery: evidence from microscopic studies and in vivo measurements [0.03%]
近红外自体荧光允许在手术过程中检测垂体腺：来自显微研究和体内测量的证据
Veronika Alibaeva,Nadezhda Korneva,Andrey Grigoriev et al.
Veronika Alibaeva et al.
A critical challenge in endocrine neurosurgery is intraoperative discrimination between normal pituitary tissue and pituitary neuroendocrine tumors (PitNETs). Suggesting the universal persistence of near-infrared autofluorescence (NIRAF) in...
Combination of tissue-derived and shape-based parameters for subclinical keratoconus detection [0.03%]
基于组织和形态参数的隐形角膜扩张症检测方法
Juan Casado-Moreno,Ana R Arizcuren,Jos J Rozema et al.
Juan Casado-Moreno et al.
This study investigates whether combining clinically conventional shape-based tomographic parameters and image-derived descriptors extracted from raw Scheimpflug corneal images improves the detection of subclinical keratoconus (SKC). A data...
Geometry-dependent reachability, homogenization, and redundancy in multi-view photoacoustic illumination [0.03%]
基于几何的可达性、同质化和冗余多视图光声照明
Na Cao,Hui Cao
Na Cao
In deep scattering tissue, vascular geometry strongly modulates the optical fluence field, thereby complicating quantitative photoacoustic imaging and the assessment of multi-view illumination. This study establishes a geometry-consistent b...
Spatially multiplexed random-access Raman probe for in vivo tissue measurements [0.03%]
用于体内组织测量的空间复用随机访问拉曼探针
Wataru Sakata,Atsuko Fujihara,Taisuke Ota et al.
Wataru Sakata et al.
Raman spectroscopy enables label-free identification of biological tissues, but its clinical application remains limited due to low-throughput measurements. Here, we developed a spatially multiplexed random-access Raman probe that enables s...