Kate Grieve,Kostadinka Bizheva,Gereon Hüttmann et al.
Kate Grieve et al.
The guest editors introduce a feature issue on the topic of imaging of tissue and cell dynamics. © 2025 Optica Publishing Group.
Automated animal gimbal steering for retinal imaging and stimulation [0.03%]
用于视网膜成像和刺激的自动化动物稳定平台控制系统
Karteek Kunala,Gastón A Ayubi,Joel A Franco et al.
Karteek Kunala et al.
Here, we propose optomechanical devices for steering anesthetized animals during retinal imaging and/or stimulation with stationary ophthalmoscopes. Simple operating procedures ensure that the entrance pupil of the eye remains centered on t...
Longitudinal investigation of spatial memory and retinal parameters in a 5xFAD model of Alzheimer's disease reveals differences dependent on genotype and sex [0.03%]
纵向研究发现，在5XFAD型阿尔茨海默病模型中，空间记忆和视网膜参数的差异取决于基因型和性别
Georg Ladurner,Conrad W Merkle,Lucas May et al.
Georg Ladurner et al.
The retinal phenotype of Alzheimer's disease (AD), its connection to spatial memory, and the influence of sex on the phenotype are poorly understood. Here, we investigate the retina and spatial memory of 5xFAD mouse models of AD by measurin...
Structural analysis of cone photoreceptors in AO-OCT enables S-cone identification by a support vector machine classifier [0.03%]
基于支持向量机分类器的AO-OCT视网膜红锥通道光受体结构分析及识别能力研究
Qiuzhi Ji,Marcel T Bernucci,Yan Liu et al.
Qiuzhi Ji et al.
Adaptive optics optical coherence tomography (AO-OCT) enables high-resolution, 3-dimensional imaging of cone photoreceptors in the living human retina. Histological studies have shown that short-wavelength-sensitive (S) cones are structural...
High-throughput spontaneous Raman imaging of biological specimens with water background reduction [0.03%]
一种降低水背景的高通量自发拉曼成像技术用于生物样品检测
Tomoaki Okumura,Yasuaki Kumamoto,Nicholas Isaac Smith et al.
Tomoaki Okumura et al.
In multiline-illumination Raman microscopy, background signals from the out-of-focus planes limit the throughput of cell imaging. Here, we improved the throughput of cell imaging by reducing background signals originating from the sample bu...
Multimodality catheter composed of intravascular ultrasound imaging and polymer optical fiber FFR functions for the diagnosis of cardiac disease [0.03%]
一种用于心血管疾病诊断的IVUS和POF-FFR多功能导管集成系统
Weijin Chen,Xin Cheng,Ning Wang et al.
Weijin Chen et al.
In this study, we developed a minimally invasive intravascular catheter integrating ultrasonic imaging with fiber Bragg grating (FBG)-based mechanical sensing. By co-integrating a high-frequency miniature ultrasound transducer and a ZEONEX-...
Focusing optical phased array for tissue interrogation with improved side-lobe suppression and simplified beam steering [0.03%]
一种侧瓣抑制性能改善且光束扫描操作更简单的聚焦型光学相控阵用于组织探测
Pedram Hosseini,Alireza Tabatabaei Mashayekh,Prachi Agrawal et al.
Pedram Hosseini et al.
We implement an integrated multi-electrode array on a silicon-nitride-based photonic integrated circuit for ex-vivo retinal characterization via optical stimulation. The interrogation beam formers, based on curved grating emitters and optic...
Forest Speed,Alec Teel,Timothy Young et al.
Forest Speed et al.
We utilize periodic structured illumination with pseudo-HiLo (pHiLo) image reconstruction for in vivo voltage imaging. We demonstrate reduced signal from out-of-focus cells, which contaminates voltage activity for in-focus cells of interest...
Evaluating retinal image quality for myopia control lenses in a synthetic accommodative wavefront model [0.03%]
评估合成调节波前模型中的近视控制镜片的视网膜图像质量
María Mechó-García,Paulo Fernandes,José Manuel González-Méijome et al.
María Mechó-García et al.
This study uses a wavefront model to evaluate the effects of contact lenses on retinal image quality (RIQ) as a function of target vergence (TV). Three hundred synthetic eyes were generated using an accommodative wavefront model to simulate...
Long-wavelength oblique back-illumination microscopy for deep in vivo imaging [0.03%]
长波长倾斜背向照明显微镜在深层体内的成像中的应用
Ye-Chan Cho,Jin Hee Hong,Sungsam Kang et al.
Ye-Chan Cho et al.
Oblique back-illumination microscopy (OBM) is a label-free imaging technique that captures differential forward scattering in reflection mode to generate high-contrast pseudo-transmission images of cells and microvessels. While OBM benefits...