Next-generation endoscopic probe for detection of esophageal dysplasia using combined OCT and angle-resolved low-coherence interferometry [0.03%]
用于食管异型性检测的下一代内镜探针，结合了OCT和角度分辨低相干干涉仪
Evan T Jelly,Zachary A Steelman,Haoran Zhang et al.
Evan T Jelly et al.
Angle-resolved low-coherence interferometry (a/LCI) is an optical technique that enables depth-specific measurements of nuclear morphology, with applications to detecting epithelial cancers in various organs. Previous a/LCI setups have been...
Multi-wavelength multi-distance diffuse correlation spectroscopy system for assessment of premature infants' cerebral hemodynamics [0.03%]
用于评估早产儿脑部血流动力学的多波长多距离扩散相关光谱系统
Nikola Otic,John Sunwoo,Yujing Huang et al.
Nikola Otic et al.
Infants born at an extremely low gestational age (ELGA, < 29 weeks) are at an increased risk of intraventricular hemorrhage (IVH), and there is a need for standalone, safe, easy-to-use tools for monitoring cerebral hemodynamics. We have bui...
Enhanced model iteration algorithm with graph neural network for diffuse optical tomography [0.03%]
基于图神经网络的增强型模型迭代算法在漫射光学断层成像中的应用
Huangjian Yi,Ruigang Yang,Yishuo Wang et al.
Huangjian Yi et al.
Diffuse optical tomography (DOT) employs near-infrared light to reveal the optical parameters of biological tissues. Due to the strong scattering of photons in tissues and the limited surface measurements, DOT reconstruction is severely ill...
Exploring in-vivo infrared spectroscopy for nail-based diabetes screening [0.03%]
基于甲床的糖尿病筛选中活体红外光谱的探究
Daniela Lazaro-Pacheco,Philip F Taday,Päivi Maria Paldánius
Daniela Lazaro-Pacheco
Diabetes screening is traditionally complex, inefficient, and reliant on invasive sampling. This study evaluates near-infrared spectroscopy for non-invasive detection of glycated keratin in nails in vivo. Glycation of keratin, prevalent in ...
PDMS-embedded wearable FBG sensors for gesture recognition and communication assistance [0.03%]
嵌入式PDMS的可穿戴FBG传感器在手势识别和通信辅助中的应用
Kun Xiao,Zhuo Wang,Yudong Ye et al.
Kun Xiao et al.
This study introduces fiber Bragg grating (FBG) sensors embedded in polydimethylsiloxane (PDMS) silicone elastomer specifically engineered for recognizing intricate gestures like wrist pitch, finger bending, and mouth movement. Sensors with...
In vivo measurement of the biomechanical properties of human skin with motion-corrected Brillouin microscopy [0.03%]
运动校正的布里渊显微镜对人体皮肤生物力学特性进行活体测量
Maria N Romodina,Asha Parmar,Kanwarpal Singh
Maria N Romodina
Biomechanical testing of human skin in vivo is important to study the aging process and pathological conditions such as skin cancer. Brillouin microscopy allows the all-optical, non-contact visualization of the mechanical properties of cell...
Shuo Tang,Daniel Elson,Nicholas Durr
Shuo Tang
The editors introduce the feature issue on "Novel Techniques in Microscopy," which was the topic of a symposium held on April 24-27, 2023, in Vancouver, BC. This symposium was part of the Optics in the Life Sciences Congress. ...
Quantifying nanoscopic alterations associated with mitochondrial dysfunction using three-dimensional single-molecule localization microscopy [0.03%]
使用三维单分子定位显微镜量化与线粒体功能障碍相关的纳米级改变
Benjamin Brenner,Fengyuanshan Xu,Yang Zhang et al.
Benjamin Brenner et al.
Mitochondrial morphology provides unique insights into their integrity and function. Among fluorescence microscopy techniques, 3D super-resolution microscopy uniquely enables the analysis of mitochondrial morphological features individually...
Optical projection tomography reconstruction with few views using highly-generalizable deep learning at sinogram domain [0.03%]
使用通用性高的深度学习在sinogram域中用少量视图重构光学投影断层图像
Jiahao Sun,Fang Zhao,Lanxin Zhu et al.
Jiahao Sun et al.
Optical projection tomography (OPT) reconstruction using a minimal number of measured views offers the potential to significantly reduce excitation dosage and greatly enhance temporal resolution in biomedical imaging. However, traditional a...
Evaluating differences in optical properties of indolent and aggressive murine breast tumors using quantitative diffuse reflectance spectroscopy [0.03%]
利用定量弥散反射光谱评估惰性与侵袭性小鼠乳腺肿瘤光学特性差异
Joel Rodriguez Troncoso,Umme Marium Mim,Jesse D Ivers et al.
Joel Rodriguez Troncoso et al.
We used diffuse reflectance spectroscopy to quantify tissue absorption and scattering-based parameters in similarly sized tumors derived from a panel of four isogenic murine breast cancer cell lines (4T1, 4T07, 168FARN, 67NR) that are each ...