Tongliang Zhou,Chaoyue Zhao,Shiyi Yang et al.
Tongliang Zhou et al.
Developments in organic synthesis over the past century have greatly enabled the discovery of life-saving medicines. In this context, over the past two decades, palladium-catalyzed cross-coupling reactions have transformed the exploration o...
Harnessing Noncovalent π‑Type Interactions in Thiourea-Chloride Supramolecular Complexes: Toward the Asymmetric Dearomatization of Diazaheterocycles [0.03%]
硫脲-氯
Marta Velázquez,Pilar Elías-Rodríguez,Tomás Tejero et al.
Marta Velázquez et al.
Enantioselective dearomatization of diazaheterocycles through anion-binding catalysis has been developed. The process involves the nucleophilic addition of phosphorus nucleophiles to in situ generated N-benzoyliminium chlorides, using a ter...
How Does the Ni-Ga Alloy Structure Tune Methanol Productivity and Selectivity? [0.03%]
镍-镓合金结构如何调节甲醇产率和选择性？
Nora K Zimmerli,Andrés F Usuga,Stefano Checchia et al.
Nora K Zimmerli et al.
In this work, we assess how the structure of SiO2-supported, Ni-Ga alloys determines their activity and selectivity for the hydrogenation of CO2 to methanol. Using a hydrothermal deposition-precipitation approach followed by activation at 7...
Rh(III)-Catalyzed Alkene Anti Nucleoamidation to Access Diverse Heterocycles [0.03%]
Rh(III)催化烯烃反氨胺化合成多种杂环化合物
Noah Wagner-Carlberg,Julia R Dorsheimer,Tomislav Rovis
Noah Wagner-Carlberg
Alkene difunctionalization methods are an attractive way to rapidly build molecular complexity using readily available starting materials. One common approach is transition metal-catalyzed nucleometalation, which converts the C-C double bon...
Blasticidin S Biosynthesis Involves a Unique Interplay between a Radical SAM Dehydratase, a Transaminase and an ATP-Grasp Ligase in Order to Avoid a Futile Cycle [0.03%]
一种新的非冗余途径涉及线粒体蛋白编码基因产物参与blas生物合成
Yu-Hsuan Lee,Daan Ren,Ridao Chen et al.
Yu-Hsuan Lee et al.
Blasticidin S is a peptidyl nucleoside that blocks protein synthesis in prokaryotes and eukaryotes. It is widely used in molecular biology as a selection agent. Despite its utility, the biosynthetic origin of its 2',3'-unsaturated-4'-aminoa...
Palladium-Catalyzed Aerobic Alkene Arylboration: Coupling Aryl Boronic Acids, Alkenes, and Bis(pinacol)diboron [0.03%]
钯催化烯烃的脱氢偶联反应：芳基硼酸、烯烃和双pinacolate二硼烷的三组分偶联反应
Hoang T P Pham,Shreeja Bhatt,Kami L Hull
Hoang T P Pham
Alkyl boronic acids and esters are versatile synthetic intermediates that generally require several steps to synthesize. Three-component alkene arylboration reactions allow for the rapid synthesis of alkyl boronic esters. Herein, we report ...
Ligand-Controlled Nondirected meta- or para-C-H Olefination of Silyl-Protected Phenols [0.03%]
导向基作用的酚芳丙基硅醚的C-H键官能团化反应
Guangrong Meng,Jie-Lun Yan,Nikita Chekshin et al.
Guangrong Meng et al.
Recent advances in ligand design have enabled Pd(II)-catalyzed non-directed C-H functionalization using arenes as the limiting reagent, but achieving catalyst control over the site-selectivity in these transformations remains a significant ...
Computationally Designed Peroxygenases That Exhibit Diverse and Selective Terpene Oxyfunctionalization [0.03%]
计算设计的过氧化物酶可实现萜类化合物多样的选择性官能化
Judith Münch,Jordi Soler,Ofir Gildor-Cristal et al.
Judith Münch et al.
The selective oxyfunctionalization of terpenes remains a major challenge in chemical synthesis and is of significant industrial importance. This study presents a computational enzyme design approach based on an AlphaFold2 model of an unspec...
Water Oxidation and Degradation Mechanisms of BiVO4 Photoanodes in Bicarbonate Electrolytes [0.03%]
碳酸盐电解质中BiVO4光阳极的水氧化和降解机制
Guanda Zhou,Clara C Aletsee,Anna Lemperle et al.
Guanda Zhou et al.
The photoelectrochemical hydrogen peroxide evolution reaction (HPER) has attracted increasing attention as an environmentally friendly approach to generate a commercially and industrially valuable water oxidation product. BiVO4 photoanodes ...
General, Quantified Structure-Performance Correlations for Synergistic Heteronuclear Electro‑, Polymerization, and Asymmetric Catalysts [0.03%]
协同异核电、聚合和手性催化剂的通用性能构效关系模型
Katharina H S Eisenhardt,Francesca Fiorentini,Frederica Butler et al.
Katharina H S Eisenhardt et al.
Intermetallic synergy can be useful to both enhance catalytic performance and access diverse chemistries, but understanding and predicting the most effective metal combinations remains a challenge. This perspective focuses on a common class...