Altering Active-Site Loop Dynamics Enhances Standalone Activity of the Tryptophan Synthase Alpha Subunit [0.03%]
改变活性位点环状结构的动力学以增强色氨酸合成酶α亚基的单独活性
Cristina Duran,Thomas Kinateder,Caroline Hiefinger et al.
Cristina Duran et al.
The α-subunit (TrpA) of the allosterically regulated bifunctional tryptophan synthase αββα enzyme catalyzes the retro-aldol cleavage of indole-glycerol phosphate (IGP) to d-glyceraldehyde 3-phosphate (G3P) and indole. The activity of t...
Repurposing a Fully Reducing Polyketide Synthase toward 2-Methyl Guerbet-like Lipids [0.03%]
将全还原型聚酮合酶重编程用于合成2-甲基古埃伯特类脂质
Michael A Herrera,Stephen McColm,Louise-Marie Craigie et al.
Michael A Herrera et al.
In nature, thousands of diverse and bioactive polyketides are assembled by a family of multifunctional, "assembly line" enzyme complexes called polyketide synthases (PKS). Since the late 20th century, there have been several attempts to dec...
Correction to "Impact of Sn Lewis Acid Sites on the Dehydration of Cyclohexanol" [0.03%]
“SnLewis酸位点对环己醇脱水作用的影响”一文的更正
Karen A Resende,Ruixue Zhao,Yue Liu et al.
Karen A Resende et al.
[This corrects the article DOI: 10.1021/acscatal.4c01608.]. © 2024 The Authors. Published by American Chemical Society.
Published Erratum
ACS catalysis. 2024 Oct 28;14(22):16663. DOI:10.1021/acscatal.4c05977 2024
Mechanistic Studies and Identification of Catalyst Deactivation Pathways for Pyridine(diimine) Iron Catalyzed C(sp2)-H Borylation [0.03%]
吡啶二亚胺铁催化C(sp2)-H硼化反应的机理研究及催化剂失活途径分析
Tianyi Zhang,Tyler P Pabst,Jordan M Hoyt et al.
Tianyi Zhang et al.
The synthesis and application of aryl-substituted pyridine(diimine) iron complexes (RPDI)FeCH3 to the catalytic borylation of heteroarenes under thermal conditions is described. Improvements in catalyst design and performance were guided by...
General and Practical Route to Diverse 1-(Difluoro)alkyl-3-aryl Bicyclo[1.1.1]pentanes Enabled by an Fe-Catalyzed Multicomponent Radical Cross-Coupling Reaction [0.03%]
一种通用且实用的方法，用于通过Fe催化的自由基交叉偶联反应制备多样的1-(二氟代)烷基-3-芳基双环[1.1.1]戊烷
Angel Rentería-Gómez,Wes Lee,Shuai Yin et al.
Angel Rentería-Gómez et al.
Bicyclo[1.1.1]pentanes (BCPs) are of great interest to the agrochemical, materials, and pharmaceutical industries. In particular, synthetic methods to access 1,3-dicarbosubsituted BCP-aryls have recently been developed, but most protocols r...
Analyzing the Temperature Dependence of Titania Photocatalysis: Kinetic Competition between Water Oxidation Catalysis and Back Electron-Hole Recombination [0.03%]
分析TiO2光催化温度依赖性：水分解催化与电子空穴复合动力学竞争研究
Yohei Cho,Tianhao He,Benjamin Moss et al.
Yohei Cho et al.
This study examines the kinetic origins of the temperature dependence of photoelectrochemical water oxidation on nanostructured titania photoanodes. We observe that the photocurrent is enhanced at 50 °C relative to 20 °C, with this enhanc...
A Dynamic Loop in Halohydrin Dehalogenase HheG Regulates Activity and Enantioselectivity in Epoxide Ring Opening [0.03%]
动态互变异构环调控卤代hydrat酶HheG催化的环氧合酶活性和对映选择性反应
Marcel Staar,Lina Ahlborn,Miquel Estévez-Gay et al.
Marcel Staar et al.
Halohydrin dehalogenase HheG and its homologues are remarkable enzymes for the efficient ring opening of sterically demanding internal epoxides using a variety of nucleophiles. The enantioselectivity of the respective wild-type enzymes, how...
Efficient Dehydration of 1-Phenylethanol to Styrene by Copper(II) and Zinc(II) Fused-Bisoxazolidine Catalysts [0.03%]
铜（II）和锌（II）联双氧唑烷催化剂高效催化苯乙醇脱水制苯乙烯反应
Aurodeep Panda,Caroline R Wood,William W Brennessel et al.
Aurodeep Panda et al.
The air-stable copper(II) catalyst [Cu(mesoFOX-L1)(MeCN)][OTf]2 (2a) is prepared from a fused meso-dipyridylbisoxazolidine (mesoFOX-L1) and CuBr2, followed by treatment with AgOTf. The compound is a catalyst for the dehydration of 1-phenyle...
Autocatalytic Activation of a Ruthenium-PNN-Pincer Hydrogenation Catalyst [0.03%]
钌PNN钳氢化催化剂的自动催化活化作用
Jose Fernando Carbajal Perez,Fallyn L Kirlin,Eamon F Reynolds et al.
Jose Fernando Carbajal Perez et al.
In this article, we describe a detailed experimental and computational study of the activation mechanism for a highly active pincer ruthenium(0) precatalyst for the hydrogenation of polar organic compounds. The precatalyst activates by reac...
Federico Dattila,Alessia Fortunati,Federica Zammillo et al.
Federico Dattila et al.
Electrochemical CO2 reduction (CO2R) allows us to close the carbon cycle and store intermittent renewable energy into chemical products. Among these, syngas, a mixture of hydrogen and carbon monoxide, is particularly valuable due to its hig...