Ni/Ti Dual Catalyzed Cross-Electrophile Coupling Between Unactivated Alkyl Chlorides and Aryl Halides [0.03%]
非活化烷基氯与芳基卤的交叉偶联反应研究:Ni/Ti双催化体系的应用探索
Devi Oniani,Xiaofan Jia,Emily L Mane et al.
Devi Oniani et al.
A dual Ni/Ti-catalyzed method for cross-electrophile coupling (XEC) of primary and secondary alkyl chlorides and aryl halides is described. This is a rare example of a thermal XEC reaction that directly couples unactivated alkyl chlorides, ...
Biosynthesis of 6-thioguanine: characterizing two intermediates involved in its thioamide formation reaction [0.03%]
6-硫鸟嘌呤生物合成：表征其硫胺形成反应中涉及的两种中间体
Kelin Li,Juan Lopez,Zion Kang et al.
Kelin Li et al.
6-Thioguanosine 5'-monophosphate (6-TGMP) is the biologically active nucleotide form of the antimetabolite 6-thioguanine produced by Erwinia amylovorans. The YcfA-YcfC enzymatic pair catalyzes the incorporation of the thioamide functional g...
Photoredox-Neutral Platform for Direct Decarboxylative Cyclopropanation via Acridine-Iron Dual Catalysis [0.03%]
基于吖啶-铁双催化的直接脱羧环丙烷化反应平台
Kamal Bhatt,Hariharan Mahendran,Tamal Das et al.
Kamal Bhatt et al.
A photoredox-neutral approach to cyclopropanes from in situ generated non-stabilized carbenes via a new acridine-iron dual catalytic system is reported. This strategy merges the oxidative decarboxylation of bench-stable carboxylic acids wit...
C(sp3)-H Carboxylation via Carbene/Photoredox Cooperative Catalysis [0.03%]
通过卡宾/光氧化还原协同催化实现C( sp 3 )-H羧基化反应
Cullen R Schull,Jing Cao,Sophia R Mitton-Fry et al.
Cullen R Schull et al.
C(sp3)-H bond functionalization is a powerful strategy for the synthesis of organic compounds due to their abundance in simple starting materials. Photoredox catalysis has led to a diverse array of enabling C(sp3)-H activation strategies; h...
Catalytic Triad-Inspired Nanozyme Catalysts for Ester Hydrolysis in Organic Solvent Mixtures [0.03%]
受催化三联体启发的有机溶剂混合物酯水解纳米酶催化剂
Hoya Ihara,Carlos A Huang-Zhu,Tianwei Yan et al.
Hoya Ihara et al.
We synthesized a series of molecular nanozyme catalysts containing functional groups (imidazole, carboxylic acid, and hydroxyl groups) inspired by the catalytic triad found in natural serine hydrolases. Different structural features were in...
Gold(I)-Catalyzed Intermolecular Reactions of Alkynes with Carbon Nucleophiles: What We Knowand What We Don't [0.03%]
金(I)催化下的炔烃与碳亲核试剂的反应：我们所知及未知的事情
Jesús Rodrigalvarez,Anna Arnanz,Gala Ogalla et al.
Jesús Rodrigalvarez et al.
We present an overview of the scope, limitations, and challenges associated with gold-(I)-catalyzed intermolecular reactions involving alkynes and alkenes, or alkynes with other alkynes, as well as mechanistically related transformations wi...
Insights into the Reactivity of Brookite TiO2 Nanorods in Liquid Water from Ab Initio Molecular Dynamics Simulations [0.03%]
从头算分子动力学模拟揭示板钛矿TiO2纳米线在液态水中的反应性机制
Lorenzo Agosta,Giuseppe Zollo,Annabella Selloni
Lorenzo Agosta
Brookite TiO2, a rare natural polymorph of TiO2, has been reported to be an excellent photocatalyst for the production of hydrogen from water and aqueous alcohol solutions, especially when it is reduced and synthesized in the form of nanoro...
Oxygen Reduction to Hydrogen Peroxide on Hydrophilic Carbon Fiber Paper: Dependence of the Mechanism and Active Site Stability on Electrolyte pH and Potassium Ion Concentration [0.03%]
氢氧化学亲水性碳纤维纸上的还原机制及活性位点稳定性对电解质pH值和钾离子浓度的依赖关系研究
Connor P Cox,Madeleine K Wilsey,Kendra R Watson et al.
Connor P Cox et al.
Electrocatalytic H2O2 synthesis enables decentralized production and reduces reliance on energy-intensive large-scale infrastructure. Practical application, however, requires catalyst materials that are affordable, scalable, and durable. He...
Metallic Pd-Cu Alloy Phases Drive Selective Heterogeneous Electrochemical Ketonization of 1‑Butene [0.03%]
金属Pd-Cu合金相可选择性电化学异丁烯酮化反应
Chenyu Jiang,Benjamin Moss,Alexis Lindenfelser et al.
Chenyu Jiang et al.
Electrification of 2-butanone synthesis via ketonization of 1-butene offers a viable pathway to reduce emissions associated with its production as a commodity chemical and enhance its prospects as a clean carbon-based synthetic fuel. Howeve...
Generative Artificial Intelligence-Empowered Virtual Evolution of Enzyme with the VERnet Model [0.03%]
基于VERnet模型的酶虚拟进化生成式人工智能方法
Chang Li,Wenfeng Xu,Hang Yang et al.
Chang Li et al.
Large language models (LLMs) have demonstrated their limitations in addressing the design of active proteins that rely on intricate intramolecular interactions, particularly in the engineering of biocatalysts. Conducting real-world studies ...