MicroRNA26a Overexpression Hastens Osteoblast Differentiation Capacity in Dental Stem Cells [0.03%]
微小核糖核酸26a过表达促进牙源性干细胞向成骨细胞分化的能力
Steven Kaufman,Peter Chang,Elisha Pendleton et al.
Steven Kaufman et al.
Dental pulp stem cells (DPSCs) and stem cells from human exfoliated deciduous teeth (SHED) are a source of mesenchymal stem cells with the potential to differentiate into several cell types. We initially isolated SHED cells and compared the...
Ameliorative Effects of Extracellular Vesicles Derived from Mesenchymal Stem Cells on Apoptosis and Differentiation of Osteoblasts Treated with CoCl2 [0.03%]
CoCl2处理的骨髓间充质干细胞来源细胞外囊泡对成骨细胞凋亡及分化的影响
Qicheng Li,Wei Zhang,Jin Deng et al.
Qicheng Li et al.
Severe osteoporotic fracture occurring in sites with inadequate blood supply can cause irreversible damage to cells, particularly osteoblasts, with current drug and surgical interventions exhibiting limitations for elderly individuals. As p...
Functions of Key Enzymes of Glycolytic Metabolism in Tumor Microenvironment [0.03%]
糖酵解代谢关键酶在肿瘤微环境中的功能
Wenxin Xu,Jialei Weng,Minghao Xu et al.
Wenxin Xu et al.
The tumor microenvironment (TME) plays a crucial role in tumor initiation, growth and metastasis. Metabolic enzymes involved in tumor glycolytic reprogramming, including hexokinase, pyruvate kinase, and lactate dehydrogenase, not only play ...
Jere Weltner,Ras Trokovic
Jere Weltner
By screening a CRISPR knockout library for mouse pluripotent reprogramming roadblock genes, Kaemena et al. identify the KRAB-ZFP factor Zfp266 as a suppressor of efficient reprogramming. Furthermore, by analyzing DNA binding and chromatin o...
The Emerging Biological Functions of Exosomes from Dental Tissue-Derived Mesenchymal Stem Cells [0.03%]
牙源性间充质干细胞外泌体的新兴生物学功能
Shu Ma,Yidi Jiang,Yuyan Qian et al.
Shu Ma et al.
Exosomes are one kind of small-cell extracellular membranous vesicles that can regulate intercellular communication and give rise to mediating the biological behaviors of cells, involving in tissue formation, repair, the modulation of infla...
Reprogramming Stars #11: Teaming Up to Uncover the Epitranscriptomics of Reprogramming-An Interview with Dr. Miguel Fidalgo and Dr. Diana Guallar [0.03%]
重编星星第11期：联手揭开重编程表转录组学的面纱——对Fidalgo博士和Guallar博士的采访
Miguel Fidalgo,Diana Guallar,Carlos-Filipe Pereira
Miguel Fidalgo
Production of MSTN Gene-Edited Embryos of Buffalo Using the CRISPR/Cas9 System and SCNT [0.03%]
利用CRISPR/Cas9系统编辑水 buffalo MSTN基因和体细胞克隆生产基因编辑胚胎
Seema Dua,Sonu Bansal,Devika Gautam et al.
Seema Dua et al.
The clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 system and somatic cell nuclear transfer (SCNT) have been used to produce genome-edited farm animal species for improved production and health traits; however, thes...
Treatments of Porcine Nuclear Recipient Oocytes and Somatic Cell Nuclear Transfer-Generated Embryos with Various Reactive Oxygen Species Scavengers Lead to Improvements of Their Quality Parameters and Developmental Competences by Mitigating Oxidative Stress-Related Impacts [0.03%]
多种活性氧清除剂处理受体卵母细胞和克隆胚胎通过减轻氧化压力导致其质量和发育潜能的改善
Seung-Hwan Oh,Seung-Eun Lee,Dong-Hun Han et al.
Seung-Hwan Oh et al.
This study investigated the antioxidant effects of β-cryptoxanthin (BCX), hesperetin (HES), and icariin (ICA), and their effects on in vitro maturation of porcine oocytes and subsequent embryonic development of somatic cell nuclear transfe...
Evaluation of All Human Transcription Factors on the Directed Differentiation of Pluripotent Stem Cells [0.03%]
评估全部人类转录因子在多能干细胞定向分化中的作用
Rodrigo L Dos Santos
Rodrigo L Dos Santos
A Fundamental Research in In Vitro Spermatogonial Stem Cell Culturing: What Are Clump Cells? [0.03%]
体内 spermatogonial 干细胞培养的基本研究：什么是 cell clumps？
Kiana Sojoudi,Hossein Azizi,Thomas Skutella
Kiana Sojoudi
Spermatogonial stem cells (SSCs) are a small group of testicular cells located in the basement membrane of seminiferous tubules and can balance self-renewal and differentiation during spermatogenesis. Our in vitro culture experiments of mou...