Direct Cardiac Reprogramming in the Omics Era: Advances, Mechanisms, and Applications [0.03%]
组学时代的心脏直接重编程研究：进展、机制和应用
Chelsea Li,Li Qian
Chelsea Li
Cardiovascular disease remains the leading cause of death worldwide, with its disease burden continuing to rise. After cardiac injury, most commonly ischemia from myocardial infarction, irreversible loss of cardiomyocytes (CMs) occurs, and ...
Dong Yu,Wenpei Liu,Feng Liu et al.
Dong Yu et al.
Hematopoietic cell reprogramming, defined as the conversion from one hematopoietic or immune cell type into another, has been shown to hold transformative potential for advancing our understanding of hematopoiesis, disease mechanisms, and t...
Reprogramming Stars #26: Understanding the Reprogramming Privilege-An Interview with Dr. Shangqin Guo [0.03%]
从头开始：编程特权——与郭商勤博士的访谈（二十六）
Shangqin Guo,Mariana Lopes,Carlos-Filipe Pereira
Shangqin Guo
Induction of Neuronal Differentiation of Human Dermal Mesenchymal Stem Cells by a Defined Arginine-Aspartate-Phenylalanine Peptide Mixture in Vitro [0.03%]
体外用精确定义的精氨酸天冬氨酸苯丙氨酸混合多肽诱导人皮肤间充质干细胞向神经元分化
Xiaoru Pan,Shengxiu Liu,Rong Zhang et al.
Xiaoru Pan et al.
The aim of this study is to investigate the effects of a peptide mixture composed of arginine (Arg), aspartic acid (Asp), and phenylalanine (Phe) on the proliferation and neural differentiation of human dermal mesenchymal stem cells (HDMSCs...
In Vitro Generation of Brown and Beige Adipocytes via Cellular Reprogramming [0.03%]
体外通过细胞重编程产生棕色和米色脂肪细胞
Kurahashi Toshihiro,Yoshinori Harada,Ping Dai
Kurahashi Toshihiro
The global prevalence of obesity continues to rise with no signs of slowing. Because obesity is a risk factor for numerous diseases, it diminishes both quality of life and life expectancy. Hence, developing effective strategies for obesity ...
Reprogramming Stars #25: Modeling Brain Aging with Direct Reprogramming of Skin Cells into Neurons-An Interview with Dr. Jerome Mertens [0.03%]
从皮肤细胞直接重编程为神经元模拟大脑衰老——对Jerome Mertens博士的采访
Jerome Mertens,Mariana Lopes,Carlos-Filipe Pereira
Jerome Mertens
Cellular Reprogramming and Microfluidics Enable Large-Scale Blastoid Production from Aged Donors [0.03%]
细胞重组和微流控技术使利用供体老化细胞大规模生成类囊胚成为可能
Marcelo Tigre Moura
Marcelo Tigre Moura
Blastoids are stem cell-based cellular models that resemble preimplantation embryos and have the potential to ease the investigation of developmental processes and associated diseases. Despite the fast-paced progress of blastoid technology ...
Reprogramming Stars #24: Pluripotency and Oncogenic Transformation: A Series of Intermingling Events-An Interview with Dr. Fabrice Lavial [0.03%]
重编程恒星第24期：多能性与肿瘤发生：交织事件系列——对Fabrice Lavial博士的采访
Fabrice Lavial,Mariana Lopes,Carlos-Filipe Pereira
Fabrice Lavial
Clinical Application of Cell Therapy in the Treatment of Female Reproductive Diseases: A Systematic Review [0.03%]
细胞治疗在女性生殖系统疾病中的临床应用：系统评价研究
Fatemeh Saberi,Zeinab Dehghan,Shayesteh Mehdinejadiani et al.
Fatemeh Saberi et al.
Reproductive disorders affect millions of women worldwide, playing a crucial role in determining female fertility health and quality of life. Conventional methods such as surgery, hormone therapy, and assisted reproductive technologies can ...