Abnormal levels of transcript abundance of developmentally important genes in various stages of preimplantation bovine somatic cell nuclear transfer embryos [0.03%]
发育重要基因在体细胞核移植胚胎各阶段转录本异常表达水平检测
Kenneth I Aston,Guan-Peng Li,Brady A Hicks et al.
Kenneth I Aston et al.
Based on microarray data comparing gene expression of fibroblast donor cells and bovine somatic cell nuclear transfer (SCNT) and in vivo produced (AI) blastocysts, a group of genes including several transcription factors was selected for ev...
Yu-Qiang Li
Yu-Qiang Li
The present article reviews master stem cell transcription factors, their expression regulation network, and related signaling pathways with the aim of understanding the molecular mechanisms of pluripotent cell fate decisions. Oct4, Sox2, a...
Ian Wilmut
Ian Wilmut
Changes in the DNA methylation status of bovine embryos from the blastocyst to elongated stage derived from somatic cell nuclear transfer [0.03%]
体细胞核转移牛胚胎从囊胚期到伸长期DNA甲基化状态的变化
Ken Sawai,Masashi Takahashi,Satoru Moriyasu et al.
Ken Sawai et al.
The epigenetic reprogramming of the donor cell nucleus is an important factor in the development of embryos and production of normal offspring derived by somatic cell nuclear transfer (NT-SC). During early development, a dramatic reduction ...