Transdifferentiation of human amniotic epithelial cells into acinar cells using a double-chamber system [0.03%]
人羊膜上皮细胞向小叶细胞转分化——双室系统的应用
Gui-Lin Huang,Ni-Ni Zhang,Jun-Sheng Wang et al.
Gui-Lin Huang et al.
This study investigated the transdifferentiation of stem cells from human amnion tissue into functional acinar cells (ACs) using a co-culture system. Human amniotic epithelial cells (hAECs) were isolated from amnion tissue by mechanical min...
Clinical Trial
Cellular reprogramming. 2012 Aug;14(4):377-83. DOI:10.1089/cell.2011.0096 2012
Nuclear dynamics of histone H3 trimethylated on lysine 9 and/or phosphorylated on serine 10 in mouse cloned embryos as new markers of reprogramming? [0.03%]
三甲基化组蛋白H3赖氨酸9和/或组蛋白H3丝氨酸10磷酸化的动态变化成为小鼠克隆胚胎重编程的新标志？
Karlla Ribeiro-Mason,Claire Boulesteix,Vincent Brochard et al.
Karlla Ribeiro-Mason et al.
Somatic cell nuclear transfer (SCNT) is the injection of a donor nucleus into an enucleated egg. Despite the use of this technology for many years in research, it is still quite inefficient. One of the causes for this is thought to be incor...
α1,3-galactosyltransferase deficiency in germ-free miniature pigs increases N-glycolylneuraminic acids as the xenoantigenic determinant in pig-human xenotransplantation [0.03%]
无菌环境下极小猪α1，3-半乳糖基转移酶缺乏增加猪人异种移植中的异种抗原神经氨酸苷酸-alpha 2,8-聚合物的含量
Jong-Yi Park,Mi-Ryung Park,Hong-Thuy Bui et al.
Jong-Yi Park et al.
In this study, we examined whether Hanganutziu-Deicher (H-D) antigens are important as an immunogenic non-α1,3-galactose (Gal) epitope in pigs with a disrupted α1,3-galactosyltransferase gene. The targeting efficiency of the AO blood geno...
Proliferative capacity and pluripotent characteristics of porcine adult stem cells derived from adipose tissue and bone marrow [0.03%]
来源于脂肪和骨髓的成人干细胞的增殖能力和多能性特征
Lina Tang,Yupeng Yin,Haole Zhou et al.
Lina Tang et al.
Direct reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) provides an invaluable resource for regenerative medicine. Because of some ethical and logistical barriers, human iPSCs cannot be used to generate a chimera, wh...
Recombinant rabbit leukemia inhibitory factor and rabbit embryonic fibroblasts support the derivation and maintenance of rabbit embryonic stem cells [0.03%]
重组兔白血病抑制因子和兔胚胎成纤维细胞支持兔胚胎干细胞的分离及增殖
Fei Xue,Yinghong Ma,Y Eugene Chen et al.
Fei Xue et al.
The rabbit is a classical experimental animal species. A major limitation in using rabbits for biomedical research is the lack of germ-line-competent rabbit embryonic stem cells (rbESCs). We hypothesized that the use of homologous feeder ce...
Human mesenchymal stem cells derived from limb bud can differentiate into all three embryonic germ layers lineages [0.03%]
取自动物肢体芽的间充质干细胞可以向三个胚层分化
Fei Jiao,Juan Wang,Zhao-Lun Dong et al.
Fei Jiao et al.
Mesenchymal stem cells (MSCs) have been isolated from many sources, including adults and fetuses. Previous studies have demonstrated that, compared with their adult counterpart, fetal MSCs with several remarkable advantages may be a better ...
Clinical Trial
Cellular reprogramming. 2012 Aug;14(4):324-33. DOI:10.1089/cell.2012.0004 2012
Kinetic analysis of porcine fibroblast reprogramming toward pluripotency by defined factors [0.03%]
用定义因子法分析猪成纤维细胞向多能性转变的动态过程
De Cheng,Zhenzhen Li,Yajun Liu et al.
De Cheng et al.
Induced pluripotent stem cells (iPSCs) are generated from somatic cells through ectopic expression of defined transcription factors. So far, many iPSC lines have been established in various species, including porcine. However, the molecular...
Peng Zhang,Yidi Zhang,Hongwei Dou et al.
Peng Zhang et al.
Production of transgenic animals via somatic cell nuclear transfer (SCNT) has been adapted worldwide, but this application is somewhat limited by its relatively low efficiency. In this study, we used handmade cloning (HMC) established previ...
Clinical Trial
Cellular reprogramming. 2012 Jun;14(3):258-66. DOI:10.1089/cell.2011.0073 2012
Nuclear transfer with apoptotic bovine fibroblasts: can programmed cell death be reprogrammed? [0.03%]
凋亡牛纤维细胞的核移植：程序性细胞死亡能被重新编程吗？
Moyses dos Santos Miranda,Fabiana Fernandes Bressan,Tiago Henrique Camara De Bem et al.
Moyses dos Santos Miranda et al.
Cell death by apoptosis is considered to be irreversible. However, reports have indicated that its reversibility is possible if the cells have not yet reached the "point of no return." In order to add new information about this topic, we us...
Human amniotic epithelial cells are reprogrammed more efficiently by induced pluripotency than adult fibroblasts [0.03%]
人羊膜上皮细胞比成人纤维母细胞更容易被重编程为诱导多能干细胞
Charles A Easley th,Toshio Miki,Carlos A Castro et al.
Charles A Easley th et al.
Cellular reprogramming from adult somatic cells into an embryonic cell-like state, termed induced pluripotency, has been achieved in several cell types. However, the ability to reprogram human amniotic epithelial cells (hAECs), an abundant ...