Differentiation of Urine-Derived Human Induced Pluripotent Stem Cells to Alveolar Type II Epithelial Cells [0.03%]
人尿诱导多能干细胞向肺泡Ⅱ型上皮细胞分化
Chen Wang,Feilong Hei,Zhihai Ju et al.
Chen Wang et al.
Human alveolar type II (AT II) epithelial cells are valuable for the cellular therapy of lung disease. Human induced pluripotent stem cells (iPSCs) have the ability to generate AT II cells that can be used in modeling and treatment of lung ...
Optimized Protocols for In Vitro Maturation of Rat Oocytes Dramatically Improve Their Developmental Competence to a Level Similar to That of Ovulated Oocytes [0.03%]
优化的体外成熟方案可显著提高小鼠卵母细胞的发育潜能至接近体内排卵的水平
Guang-Zhong Jiao,Wei Cui,Rui Yang et al.
Guang-Zhong Jiao et al.
The developmental capacity of in vitro-matured (IVM) oocytes is markedly lower than that of their in vivo-matured (IVO) counterparts, suggesting the need for optimization of IVM protocols in different species. There are few studies on IVM o...
Comparative Study
Cellular reprogramming. 2016 Feb;18(1):17-29. DOI:10.1089/cell.2015.0055 2016
Recombinant Human Bone Morphogenetic Protein 6 Enhances Oocyte Reprogramming Potential and Subsequent Development of the Cloned Yak Embryos [0.03%]
重组人骨形态发生蛋白6增强卵母细胞重编程潜能及克隆牦牛胚胎的后续发育
Yangyang Pan,Honghong He,Yan Cui et al.
Yangyang Pan et al.
This study investigated the effects of bone morphogenetic protein 6 (BMP6) supplementation in the medium during in vitro maturation (IVM) on the developmental potential of oocytes and in the subsequent development of cloned yak embryos. Cum...
Factors Determining the Efficiency of Porcine Somatic Cell Nuclear Transfer: Data Analysis with Over 200,000 Reconstructed Embryos [0.03%]
影响体细胞克隆猪效率的因素分析（基于20多万枚重构胚的统计分析）
Tianbin Liu,Hongwei Dou,Xi Xiang et al.
Tianbin Liu et al.
Data analysis in somatic cell nuclear transfer (SCNT) research is usually limited to several hundreds or thousands of reconstructed embryos. Here, we report mass results obtained with an established and consistent porcine SCNT system (handm...
Roles of p53 and ASF1A in the Reprogramming of Sheep Kidney Cells to Pluripotent Cells [0.03%]
p53和ASF1A在羊肾细胞重编程为多能干细胞中的作用研究
Huijun Shi,Qiang Fu,Guozhong Li et al.
Huijun Shi et al.
Since the first report of induced pluripotent stem cells (iPSCs) by Takahashi and Yamanaka, numerous attempts have been made to derive iPSCs from other species via the ectopic expression of defined factors. Sheep iPSCs (siPSCs) have signifi...
Derivation of Rabbit Embryonic Stem Cells from Vitrified-Thawed Embryos [0.03%]
玻璃化冷冻融解兔胚胎的诱导多能干细胞系的建立
Fuliang Du,Chien-Hong Chen,Yi Li et al.
Fuliang Du et al.
The rabbit is a useful animal model for regenerative medicine. We previously developed pluripotent rabbit embryonic stem cell (rbESC) lines using fresh embryos. We also successfully cryopreserved rabbit embryos by vitrification. In the pres...
Direct Conversion of Equine Adipose-Derived Stem Cells into Induced Neuronal Cells Is Enhanced in Three-Dimensional Culture [0.03%]
马脂肪源性干细胞在三维培养中直接转化为诱导神经元细胞的效果增强
Gayle F Petersen,Bryan J Hilbert,Gareth D Trope et al.
Gayle F Petersen et al.
The ability to culture neurons from horses may allow further investigation into equine neurological disorders. In this study, we demonstrate the generation of induced neuronal cells from equine adipose-derived stem cells (EADSCs) using a co...
Understanding the Molecular Basis of Heterogeneity in Induced Pluripotent Stem Cells [0.03%]
了解诱导多能干细胞异质性的分子基础
Kannan V Manian,Syed Mohammed Musheer Aalam,Sumitha P Bharathan et al.
Kannan V Manian et al.
Reprogramming of somatic cells to generate induced pluripotent stem cells (iPSCs) has considerable latency and generates epigenetically distinct partially and fully reprogrammed clones. To understand the molecular basis of reprogramming and...
Peculiarity of Porcine Amniotic Membrane and Its Derived Cells: A Contribution to the Study of Cell Therapy from a Large Animal Model [0.03%]
猪胎盘羊膜的特殊性及其细胞系建立：大型动物细胞治疗模型的研究贡献
Anna Lange-Consiglio,Bruna Corradetti,Sabrina Bertani et al.
Anna Lange-Consiglio et al.
The aim of this work was to provide, for the first time, a protocol for isolation and characterization of stem cells from porcine amniotic membrane in view of their potential uses in regenerative medicine. From three samples of allanto-amni...