Pig Induced Pluripotent Stem Cell-Derived Neural Rosettes Parallel Human Differentiation Into Sensory Neural Subtypes [0.03%]
猪诱导多能干细胞来源的神经芽胞平行人的感觉神经亚型分化
Robin L Webb,Amalia Gallegos-Cárdenas,Colette N Miller et al.
Robin L Webb et al.
The pig is the large animal model of choice for study of nerve regeneration and wound repair. Availability of porcine sensory neural cells would conceptually allow for analogous cell-based peripheral nerve regeneration in porcine injuries o...
Mitogen-Activated Protein Kinase Activity Is Not Essential for the First Step of Nuclear Reprogramming in Bovine Somatic Cell Nuclear Transfer [0.03%]
MAPK活性对于牛体细胞核移植重编程第一步并非必需
Tetsuya Tani,Yoko Kato
Tetsuya Tani
For reprogramming a somatic nucleus during mammalian cloning, metaphase of the second meiotic division (MII) oocytes has been widely used as recipient cytoplasm. High activity of maturation-promoting factor (MPF) and mitogen-activated prote...
An Overview on Current Issues and Challenges of Endothelial Progenitor Cell-Based Neovascularization in Patients with Diabetic Foot Ulcer [0.03%]
糖尿病足溃疡患者内皮祖细胞基质新生血管化的现状、问题与挑战综述
Sushant Kumar Das,Yi Feng Yuan,Mao Quan Li
Sushant Kumar Das
Diabetic foot ulcer's impaired wound healing, which leads to the development of chronic non-healing wounds and ultimately amputation, is a major problem worldwide. Although recently endothelial progenitor cell-derived cell therapy has been ...
Recent Advances in Therapeutic Applications of Induced Pluripotent Stem Cells [0.03%]
诱导多能干细胞在治疗应用方面的最新进展
Farzaneh Rami,Shamsi Naderi Beni,Mahboobeh Mojaver Kahnamooi et al.
Farzaneh Rami et al.
Induced pluripotent stem (iPS) cells are generated by reprogramming of differentiated somatic cells. These cells are identical to human embryonic stem cells (hESCs) in gene expression pattern and the ability to differentiate. iPS cells can ...
Abortive Spontaneous Egg Activation: An Emerging Biological Threat for the Existence of Mammals [0.03%]
流产型卵子自发激活化:一种新兴的生物威胁,危及哺乳动物的生存
Shilpa Prasad,Meenakshi Tiwari,Shail K Chaube
Shilpa Prasad
Mammals are important for balancing the natural ecosystem, but in the past few decades, several species have rapidly been entered under threatened category worldwide. The environmental changes, loss of natural habitats, human activities, an...
Muse Cells Derived from Dermal Tissues Can Differentiate into Melanocytes [0.03%]
由真皮组织衍生的Muse细胞可分化为黑色素细胞
Ting Tian,Ru-Zhi Zhang,Yu-Hua Yang et al.
Ting Tian et al.
The objective of the authors has been to obtain multilineage-differentiating stress-enduring cells (Muse cells) from primary cultures of dermal fibroblasts, identify their pluripotency, and detect their ability to differentiate into melanoc...
Intermediate Reprogramming of Mouse Skin Fibroblasts into Stem-Like Cells by Bone Morphogenetic Protein 4 [0.03%]
骨形态发生蛋白4介导的小鼠皮肤成纤维细胞向干细胞样细胞的中间重编程
Seung-Eun Lee,Sang-Jun Uhm,Yeo-Jin Son et al.
Seung-Eun Lee et al.
Specific transcription factors are sufficient to reprogram fully induced pluripotent stem cells or other types of cells. These findings raise the question of whether chemical molecules or proteins can replace transcription factors to alter ...
Effects of Alcohol on Mitochondrial Functions of Cumulus Cells in Mice [0.03%]
酒精对小鼠 cumulus 细胞线粒体功能的影响
Wanlu Xu,Lihui Huo,Jingjing Li et al.
Wanlu Xu et al.
Alcohol is an important compound used in food, agriculture, and medicine. In this study, we investigated the effect of alcohol on oocyte quality in mice by exposing animals for different duration times during an estrous cycle. Cumulus-oocyt...
Comparison of Human Amniotic, Chorionic, and Umbilical Cord Multipotent Mesenchymal Stem Cells Regarding Their Capacity for Differentiation Toward Female Germ Cells [0.03%]
人胎盘多能间充质干细胞向卵母细胞分化能力的比较研究
Hamid Reza Asgari,Mohammad Akbari,Hossein Yazdekhasti et al.
Hamid Reza Asgari et al.
Placenta harbors a plentiful source of various cells with stem cells or stem-like cell properties, which can be used in therapeutic procedures and research. Mesenchymal stem cells (MSCs) have attracted much attention due to their specific d...
Comparative Study
Cellular reprogramming. 2017 Feb;19(1):44-53. DOI:10.1089/cell.2016.0035 2017
Effects of Trichostatin A and PXD101 on the In Vitro Development of Mouse Somatic Cell Nuclear Transfer Embryos [0.03%]
曲古茋素A和PXD101对体细胞克隆囊胚发育的影响
Xiaoyan Qiu,Haihong You,Xiong Xiao et al.
Xiaoyan Qiu et al.
The low success rate of animal cloning by somatic cell nuclear transfer (SCNT) is believed to be associated with aberrant epigenetic nuclear reprogramming. It has been demonstrated that treatment with histone deacetylase inhibitors (HDACis)...