NRP1 Accelerates Odontoblast Differentiation of Dental Pulp Stem Cells Through Classical Wnt/β-Catenin Signaling [0.03%]
NRP1通过经典Wnt/β-catenin信号促进牙髓干细胞的成odontoblast分化
Yihua Song,Xiaojuan Liu,Xingmei Feng et al.
Yihua Song et al.
Neuropilin-1 (NRP1) is one of the members of neuropilin family. It can combine with disparate ligands involved in regulating cell proliferation, apoptosis, and differentiation. The binding of NRP1 to Sema3A stimulates osteoblast differentia...
From Stem Cell Research to Three-Dimensional Organoids and Their Applications in Cancer Research: Meeting Report on the 9th International Meeting of the Stem Cell Network North Rhine Westphalia [0.03%]
从干细胞研究到三维类器官及其在癌症研究中的应用——.stem cell network north rhine-westfalen第九届国际会议报告
Samantha Langer,Peter A Horn,Stefan Heinrichs
Samantha Langer
Selection of Suitable Internal Control Genes for Accurate Normalization of Real-Time Quantitative PCR Data of Buffalo (Bubalus bubalis) Blastocysts Produced by SCNT and IVF [0.03%]
选择适宜的内参基因对水 buffalo 体细胞克隆囊胚和 IVF 囊胚实时荧光定量 PCR 数据进行准确校正Normalization
Tanushri Jerath Sood,Swati Viviyan Lagah,Ankita Sharma et al.
Tanushri Jerath Sood et al.
We evaluated the suitability of 10 candidate internal control genes (ICGs), belonging to different functional classes, namely ACTB, EEF1A1, GAPDH, HPRT1, HMBS, RPS15, RPS18, RPS23, SDHA, and UBC for normalizing the real-time quantitative po...
Concise Review: LIN28/let-7 Signaling, a Critical Double-Negative Feedback Loop During Pluripotency, Reprogramming, and Tumorigenicity [0.03%]
简述：LIN28/LET-7信号传导在多能性、重编程序和致瘤性过程中的重要双负反馈环机制
Maryam Farzaneh,Farnoosh Attari,Seyed Esmaeil Khoshnam
Maryam Farzaneh
MicroRNAs (miRNAs) with 20-30 nucleotides have recently emerged as the multidimensional regulators of cell fate decisions. Recent improvement in high-throughput sequencing has highlighted the potential role of LIN28/let-7 regulatory network...
Effect of POU5F1 Expression Level in Clonal Subpopulations of Bovine Fibroblasts Used as Nuclear Donors for Somatic Cell Nuclear Transfer [0.03%]
供核体细胞克隆亚群中POU5F1表达量的影响
André Luiz Sá,Rafael V Sampaio,Nathália Nogueira da Costa Almeida et al.
André Luiz Sá et al.
Somatic cell nuclear transfer (SCNT) success is partially hindered by the low epigenetic reprogramming efficiency of the donor cell. Previous studies suggest cellular heterogeneity among donor nuclei in regard to reprogramming potential, wh...
Improved Chondrogenic Potential and Proteomic Phenotype of Porcine Chondrocytes Grown in Optimized Culture Conditions [0.03%]
优化培养条件对提高猪软骨细胞软骨分化潜能及蛋白质组学表型的影响
Sehwon Koh,Molly Purser,Richard Wysk et al.
Sehwon Koh et al.
For successful cartilage tissue engineering, the ability to generate a high number of chondrocytes in vitro while avoiding terminal differentiation or de-differentiation is critical. The ability to accomplish this by using the abundant and ...
m6A RNA Modification Determines Cell Fate by Regulating mRNA Degradation [0.03%]
通过调节信使核糖核酸降解决定细胞命运的m6A修饰
Minjun Guo,Xinhui Liu,Xiaotong Zheng et al.
Minjun Guo et al.
Emerging evidence suggests that epitranscriptional modifications influence multiple cellular processes. N6-methyladenosine (m6A), as the most abundant reversible methylation of mRNA, has also been reported to play critical roles in modulati...
YY1 Is Required for Posttranscriptional Stability of SOX2 and OCT4 Proteins [0.03%]
YY1对SOX2和OCT4蛋白转录后稳定性是必需的
Mary C Wallingford,Jacob Hiller,Kun Zhang et al.
Mary C Wallingford et al.
Yinyang1 (YY1) participates in protein-DNA, protein-RNA, and protein-protein interactions and regulates developmental processes and disease mechanisms. YY1 interactions regulate a range of important biological functions, including oocyte ma...
Investigation of the Developmental Potential and Developmental Kinetics of Bovine Parthenogenetic and Somatic Cell Nuclear Transfer Embryos Using a Time-Lapse Monitoring System [0.03%]
应用时间- lapse 监测系统研究牛孤雌发育和体细胞克隆胚胎的发育潜能及动力学参数
Min-Jee Park,Eun-Young Kim,Man-Jong Kang et al.
Min-Jee Park et al.
A time-lapse monitoring system has predictive value for selecting good-quality embryos with the highest implantation potential. Using this new tool, we investigated the developmental potential and developmental kinetics of bovine parthenoge...
Combinations of Activin A or Nicotinamide with the Pancreatic Transcription Factor PDX1 Support Differentiation of Human Amnion Epithelial Cells Toward a Pancreatic Lineage [0.03%]
结合使用激活素A或烟酰胺与胰腺转录因子PDX1支持人羊膜上皮细胞向胰腺分化
Shruti Balaji,Yu Zhou,Emmanuel C Opara et al.
Shruti Balaji et al.
The differentiation of multipotent stem cells toward a pancreatic lineage provides us with an alternative cell-based therapeutic approach to type 1 diabetes and enables us to study pancreas development. The current study aims to study the e...