Menstrual Blood-Derived Mesenchymal Stem Cells Improve Endometrial Receptivity in a Mouse Model of Embryonic Implantation Dysfunction [0.03%]
月经血来源间充质干细胞改善小鼠胚胎着床障碍模型的子宫内膜容受性
Chao Ma,Yue Yi,Changji Guan
Chao Ma
The decrease of endometrial receptivity leads to repeated implantation failure (RIF) during in vitro fertilization and embryo transfer. To explore the therapeutic potential of menstrual blood-derived mesenchymal stem cells (MenSCs) in addre...
Seung-Won Lee,Jungsun Kim
Seung-Won Lee
A Transcriptional Ridge in the Waddington Landscape. The Waddington landscape model, proposed in 1957, provides a powerful framework for understanding cell fate determination (Waddington, 1957). As development progresses, cells become restr...
Sox as a Functionally Conserved Link Between Unicellular Ancestors and Human Stem Cell Control [0.03%]
Sox作为单细胞祖先与人类干细胞调控之间在功能上保守的连接
Emma U Hammarlund
Emma U Hammarlund
Stem cells are key to human tissue maintenance. Because tissue maintenance allows us to live and reproduce, stem cell control is fundamental for animal life and evolution. A team of researchers set out to explore the origins of transcriptio...
Editing the CYP19 Gene in Goat Embryos Using CRISPR/Cas9 and Somatic Cell Nuclear Transfer Techniques [0.03%]
使用CRISPR/Cas9和体细胞核移植技术编辑山羊胚胎的CYP19基因
Ahmad Pirali,Farnoosh Jafarpour,Mehdi Hajian et al.
Ahmad Pirali et al.
The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR/Cas9) system is revolutionizing genome engineering and is expected to bring significant advancements in livestock traits, including the treatment of genetic diseases. Thi...
Reprogramming Stars #21: RNA Regulatory Mechanisms That Instruct Cell Identity-An Interview with Dr. Bruno Di Stefano [0.03%]
重新编程之星#21：指导细胞身份的RNA调控机制-对Dr.Bruno Di Stefano的采访
Bruno Di Stefano,Mariana Lopes,Carlos-Filipe Pereira
Bruno Di Stefano
The Proliferation Potential of Differentiated and Undifferentiated Spermatogonial Stem Cells on Diverse Feeder Layers [0.03%]
不同饲养层上分化和未分化的精子干细胞的增殖潜力
Kiana Sojoudi,Hossein Azizi,Maryam Solaimani
Kiana Sojoudi
Spermatogonial stem cells (SSCs) play an essential role in the transfer of genetic information through generations, making studying their cellular and molecular mechanisms critical. However, since SSCs are few in mice, directly studying the...
Nearly a Century of Nuclear Transfer Research: Milestones, Applications, and Challenges [0.03%]
几乎一个世纪的核转移研究：里程碑，应用和挑战
Yiren Qin
Yiren Qin
From the first cloning of animals-salamanders-to the cloning of primates-monkeys-nuclear transfer research has spanned an extensive 96-year history. Over the course of nearly a century, it has addressed fundamental scientific questions and ...
RNA in Stow, Leukemia on the Go: P-Bodies RNA Sequestration Drives Leukemogenesis [0.03%]
藏而不露：P体通过结合RNA驱动白血病发生
Alexandre Germanos,Sowndarya Muthukumar,Cristian Bellodi
Alexandre Germanos
A novel mechanism of sequestering tumor suppressor mRNAs reveals new therapeutic vulnerabilities in leukemic cells. Keywords: ...
Molecular Mechanisms and Strategies for Inducing Neuronal Differentiation in Glioblastoma Cells [0.03%]
胶质母细胞瘤细胞神经分化的分子机制及诱导策略
Zhao-Qi Tang,Yan-Rong Ye,Yun Shen
Zhao-Qi Tang
Glioblastoma multiforme (GBM) is a highly invasive brain tumor, and traditional treatments combining surgery with radiochemotherapy have limited effects, with tumor recurrence being almost inevitable. Given the lack of proliferative capacit...
Reprogramming Stars #20: Attenuating Cancer Cell Memory and Discovering Cancer Biomarkers with Cellular Reprogramming-An Interview with Dr. Jungsun Kim [0.03%]
从头再来第20集：利用细胞重编程来消减癌细胞记忆及发现癌症生物标志物——对话金俊顺博士
Jungsun Kim,Mariana Lopes,Carlos-Filipe Pereira
Jungsun Kim