Suprachoroidal Adipose Tissue-Derived Mesenchymal Stem Cell Implantation in Patients with Dry-Type Age-Related Macular Degeneration and Stargardt's Macular Dystrophy: 6-Month Follow-Up Results of a Phase 2 Study [0.03%]
干性年龄相关性黄斑变性和斯塔加特黄斑营养不良患者接受超脉络膜植入自体脂肪组织来源间充质干细胞的Ⅱ期临床研究6个月随访结果
Ayse Oner,Zeynep Burcin Gonen,Duygu Gülmez Sevim et al.
Ayse Oner et al.
This prospective clinical case series aimed to investigate the safety and efficacy of suprachoroidal adipose tissue-derived mesenchymal stem cell (ADMSC) implantation in patients with dry-type age-related macular degeneration (AMD) and Star...
Clinical Trial
Cellular reprogramming. 2018 Dec;20(6):329-336. DOI:10.1089/cell.2018.0045 2018
Kidins220/ARMS Expression Confers Proliferation But Independent of Self-Renewal in Mouse Embryonic Stem Cells [0.03%]
Kidins220/ARMS的表达赋予小鼠胚胎干细胞增殖但不赋予自我更新能力
Jingfeng Luo,Yang Zhou,Qi Chen et al.
Jingfeng Luo et al.
Embryonic stem cells (ESCs) are characterized by their ability to self-renew and their potential to differentiate into any cell type. Therefore, identification of novel molecular markers to verify the pluripotent status of mouse ESCs (mESCs...
Treatment of Buffalo (Bubalus bubalis) Somatic Cell Nuclear Transfer Embryos with MicroRNA-29b Mimic Improves Their Quality, Reduces DNA Methylation, and Changes Gene Expression Without Affecting Their Developmental Competence [0.03%]
携带微小核糖核酸-29b模拟物的纳米颗粒处理水牛体细胞克隆胚胎改善其质量、减少DNA甲基化并改变基因表达而不影响发育潜能
Shikha Singh,Songyukta Shyam,Shrutika Sah et al.
Shikha Singh et al.
microRNA-29b (miR-29b) plays an important role in controlling DNA methylation in cells. We investigated its role during early embryonic development in buffalo embryos produced by somatic cell nuclear transfer (SCNT) and in vitro fertilizati...
Selection of Reference miRNAs for Relative Quantification in Buffalo (Bubalus bubalis) Blastocysts Produced by Hand-Made Cloning and In Vitro Fertilization [0.03%]
手吸管克隆和体外受精水牛（Bubalus bubalis）囊胚中相对定量参考miRNAs的选择
Swati Viviyan Lagah,Tanushri Jerath Sood,Prabhat Palta et al.
Swati Viviyan Lagah et al.
Very low birth rate and a high incidence of abnormalities in offspring born from cloned embryos, which have limited the application of cloning technology on a wide scale, are believed to be because of incomplete or aberrant nuclear reprogra...
Curcumin Promotes Proliferation of Adult Neural Stem Cells and the Birth of Neurons in Alzheimer's Disease Mice via Notch Signaling Pathway [0.03%]
姜黄素通过Notch信号通路促进阿尔茨海默病小鼠成体神经干细胞增殖及新生神经元的产生
Jun Li,Yazhou Han,Mingduo Li et al.
Jun Li et al.
The abnormal deposition of amyloid-β peptide, a major component of senile plaques, has been reported to be the major cause of neuronal cell death and cognitive impairment in Alzheimer's disease (AD). Adult neurogenesis is related to the am...
Han Qin,Jun Cai
Han Qin
The objective of the present work was to investigate the effect of Periostin (POSTN) silencing on autophagy in osteoblasts, and provide an experimental basis for studying the mechanism of dental eruption. The cells were divided into the fol...
Preparation of Induced Pluripotent Stem Cells Using Human Peripheral Blood Monocytes [0.03%]
人外周血单个核细胞诱导多能干细胞的建系
Sumito Isogai,Naoki Yamamoto,Noriko Hiramatsu et al.
Sumito Isogai et al.
Since induced pluripotent stem (iPS) cells have been established, in recent years, clinical transplantation of cells differentiated from iPS cells derived from human skin fibroblasts is been in progress. On the contrary, monocytes have comp...
Xian-Rong Xiong,Dao-Liang Lan,Jian Li et al.
Xian-Rong Xiong et al.
Functional reprogramming of a differentiated cell toward pluripotent cell may have long-term applications in numerous aspects, especially in regenerative medicine. Evidences accumulating from recent studies suggest that cellular extracts fr...
The Effect of Epigenetic Changes on the Extrusion of the First Polar Body in Pig Oocytes During In Vitro Maturation [0.03%]
表观遗传改变对体外成熟猪卵母细胞第一极体排出的影响
Mingzhu Xu,Jialing Qian,Linan Si et al.
Mingzhu Xu et al.
The present study was designed to investigate the comprehensive function of maternal factors of primordial germ cell 7 (PGC7) and POU5F1-POU class 5 homeobox 1 (OCT4), as well as the epigenetic modification roles on the mitosis for the extr...
Cryptochrome 1 Regulates Osteoblast Differentiation via the AKT Kinase and Extracellular Signal-Regulated Kinase Signaling Pathways [0.03%]
隐花色素1通过AKT和细胞外信号调节酶信号途径调控成骨细胞分化
Lei Zhou,Jun He,Shiwei Sun et al.
Lei Zhou et al.
The many circadian clock genes build up a network structure that controls physiological processes, such as the sleep cycle, metabolism, and hormone secretion. Cryptochrome 1 (CRY1), as one of the critical circadian proteins, is closely rela...