Effect of Allogenic Bone Marrow Mesenchymal Stem Cell Transplantation on T Cells of Old Mice [0.03%]
同种异体骨髓间充质干细胞移植对老龄小鼠T细胞的影响
Biyu Zhou,Zhenmin Zhao,Xiangyu Zhang et al.
Biyu Zhou et al.
To evaluate age-related changes in T cells and stem cell-related genes in mice and the changes in T cells and stem cell-related genes after allogenic bone marrow mesenchymal stem cell (BMSC) transplantation, BALB/c mice were divided into yo...
Comparative Study
Cellular reprogramming. 2020 Feb;22(1):30-35. DOI:10.1089/cell.2019.0055 2020
The Positive Effect of TET2 on the Osteogenic Differentiation of Human Adipose-Derived Mesenchymal Stem Cells [0.03%]
TET2通过去甲基化作用促进人脂肪来源间充质干细胞成骨分化的作用及机制研究
Li Feng,Jing Zhou,Bo Xia et al.
Li Feng et al.
This study aims to understand the possible effects of TET2 (ten-eleven translocation 2) on the osteogenic differentiation of human adipose-derived mesenchymal stem cells (ADSCs). The human ADSCs were transfected with TET2 siRNAs. The osteog...
Dysfunction of MiR-148a-NRP1 Functional Axis Suppresses Osteogenic Differentiation of Periodontal Ligament Stem Cells Under Inflammatory Microenvironment [0.03%]
MiR-148a-NRP1功能轴紊乱抑制牙周炎微环境下牙周韧带干细胞成骨分化
Liuliu Bao,Xiang Zhang,Yang Xu et al.
Liuliu Bao et al.
Periodontitis is a chronic inflammatory disease that can lead to the loss of periodontal bone tissue. The osteogenic potential of periodontal ligament stem cells (PDLSCs) is significantly decreased in periodontitis microenvironment. However...
Adipose-Derived Stem Cells Inhibited the Proliferation of Bladder Tumor Cells by S Phase Arrest and Wnt/β-Catenin Pathway [0.03%]
脂肪来源干细胞通过S期停滞和Wnt/β-连环蛋白途径抑制膀胱肿瘤细胞增殖
Tao Wang,Xi Yu,Jian Lin et al.
Tao Wang et al.
Adipose-derived stem cells (ADSCs), which are present in most organs and tissues, were evaluated as a novel medium for stem cell therapy. In this study, we investigated the effects and underlying mechanisms of ADSCs in bladder tumor (BT) ce...
Rosuvastatin Attenuates Myocardial Ischemia-Reperfusion Injury via Upregulating miR-17-3p-Mediated Autophagy [0.03%]
rosuvastatin通过上调miR-17-3p介导的自噬来缓解心肌缺血再灌注损伤
Xiaoqin Wang,Jinghan Chen,Xiaojiao Huang
Xiaoqin Wang
Myocardial diseases usually appear ischemic. Reperfusion therapy is one of the effective methods that can improve clinical therapeutic efficacy. However, reperfusion results in myocardial injury named I/R injury. Rosuvastatin (RS) is HMG-Co...
In Vitro Induction of Human Embryonic Stem Cells into the Midbrain Dopaminergic Neurons and Transplantation in Cynomolgus Monkey [0.03%]
人胚胎干细胞体外诱导黑色素神经元及猕猴移植试验
Xiaoyan Qiu,Yingquan Liu,Xiong Xiao et al.
Xiaoyan Qiu et al.
A simple, rapid, efficient, and specialized culture system was successfully developed in this study to induce human embryonic stem cells into dopaminergic neurons in vitro. It only took 5 days to generate quickly and directly a large number...
Comparison of Carcass Traits, Meat Quality, and Chemical Composition of Tissues from Progeny Derived from Cloned and Noncloned Pigs [0.03%]
克隆与非克隆猪后代的胴体性状、肉质及组织化学组成的比较分析
Ting Gu,Junsong Shi,Lvhua Luo et al.
Ting Gu et al.
Systematic studies of progeny derived from somatic cell nuclear transferred animals in their biophysical and biochemical characters are critical in assessing the safety of this kind of food. In this study, we compared the carcass traits and...
Whole Blood Transcriptome Analysis for Lifelong Monitoring in Elite Sniffer Dogs Produced by Somatic Cell Nuclear Transfer [0.03%]
用于体细胞核移植优质嗅觉工作犬终生监测的全血转录组分析
Sun-A Ock,Inchul Choi,Gi-Sun Im et al.
Sun-A Ock et al.
Reproductive cloning by somatic cell nuclear transfer (SCNT) is a valuable method to propagate service dogs with desirable traits because of higher selection rates in cloned dogs. However, incomplete reprogramming is a major barrier to SCNT...
Successful Derivation of an Induced Pluripotent Stem Cell Line from a Genetically Nonpermissive Enhanced Green Fluorescent Protein-Transgenic FVB/N Mouse Strain [0.03%]
从遗传背景不相容的EGFP转基因FVB/N小鼠中成功获得诱导多能干细胞系
Deepti Abbey,Gurbind Singh,Isha Verma et al.
Deepti Abbey et al.
The embryonic stem cell line derivation from nonpermissive mouse strains is a challenging and highly inefficient process. The cellular reprogramming strategy provides an alternative route for generating pluripotent stem cell (PSC) lines fro...
DNA Methylation of the Insulin-Like Growth Factor 2-Imprinted Gene in Trophoblast Cells of Elongated Bovine Embryo: Effects of the In Vitro Culture [0.03%]
体外培养对牛延长胚胎滋养细胞中IGF2印记基因甲基化的影响
Anelise Dos Santos Mendonça,Maurício Machaim Franco,José de Oliveira Carvalho et al.
Anelise Dos Santos Mendonça et al.
DNA methylation is an essential epigenetic mark for embryo development and can be susceptible to environment factors such as in vitro conditions. The aim of this study was to verify the effect of in vitro culture until Day (D) 14 of the dev...