The Effects of Daxx Knockout on Pluripotency and Differentiation of Mouse Induced Pluripotent Stem Cells [0.03%]
Daxx基因敲除对小鼠诱导多能干细胞多能性及分化能力的影响
Hui Liu,Zhaojun Liu,Meng Gao et al.
Hui Liu et al.
Induced pluripotent stem cell (iPSC) technology refers to the reprogramming of terminally differentiated somatic cells into pluripotent stem cells by introducing specific transcription factors that are known to regulate pluripotency, includ...
Advances in Isolation and Culture of Chicken Embryonic Stem Cells In Vitro [0.03%]
鸡胚胎干细胞的分离和体外培养研究进展
Chunxia Xiong,Mingyu Wang,Wenhui Ling et al.
Chunxia Xiong et al.
Chicken embryonic stem cells (cESCs) isolated from the egg at the stage X hold great promise for cell therapy, tissue engineering, pharmaceutical, and biotechnological applications. They are considered to be pluripotent cells with the capac...
Effect of Downregulating the Hippo Pathway Members YAP1 and LATS2 Transcripts on Early Development and Gene Expression Involved in Differentiation in Porcine Embryos [0.03%]
低表达Hippo途径成员YAP1和LATS2对猪早期胚胎发育及分化相关基因表达的影响
Natsuko Emura,Yuriko Saito,Ruri Miura et al.
Natsuko Emura et al.
In mouse development, differentiation of the inner cell mass (ICM) and trophectoderm (TE) during the transition from the morula to blastocyst stage is regulated by the Hippo pathway; however, the functions of the Hippo pathway in porcine em...
Yes-Associated Protein and PDZ Binding Motif: A Critical Signaling Pathway in the Control of Human Pluripotent Stem Cells Self-Renewal and Differentiation [0.03%]
YES相关蛋白和PDZ结合基序：调控人多能干细胞自我更新及分化的一个重要信号通路
Jia Shi,Maryam Farzaneh,Seyed Esmaeil Khoshnam
Jia Shi
Human pluripotent stem cells (hPSCs) can self-renew indefinitely to generate cells like themselves with a normal karyotype and differentiate into other types of cells when stimulated with a proper set of internal and external signals. hPSCs...
Source and Follicular Fluid Treatment During the In Vitro Maturation of Recipient Oocytes Affects the Development of Cloned Pig Embryo [0.03%]
供体来源和体外成熟培养过程中卵泡液的添加对克隆猪胚胎发育的影响
Huaxing Zhao,Shaoyi Xie,Ning Zhang et al.
Huaxing Zhao et al.
Pig cloning technique is valuable in agriculture, biomedicine, and life sciences. However, the full-term developmental efficiency of cloned pig embryos is only about 1%, which limits pig cloning application. The quality of recipient oocytes...
Comparative Study
Cellular reprogramming. 2020 Apr;22(2):71-81. DOI:10.1089/cell.2019.0091 2020
Inhibition of DNA Methyltransferase by RG108 Promotes Pluripotency-Related Character of Porcine Bone Marrow Mesenchymal Stem Cells [0.03%]
DNA甲基转移酶抑制剂RG108诱导猪骨髓间充质干细胞向多能性细胞转变相关表型的转化
Qi Li,Yanhui Zhai,Xiaxia Man et al.
Qi Li et al.
Mesenchymal stem/stromal cells (MSCs) have been identified in almost all adult human tissues and been used in numerous clinical trials for a variety of diseases. Studies have shown that MSCs would undergo cellular senescence when cultured o...
Effects of PXD101 and Embryo Aggregation on the In Vitro Development of Mouse Parthenogenetic Embryos [0.03%]
PXD101和胚胎聚合对小鼠孤雌生殖胚体外发育的影响
Xiaoyan Qiu,Xiong Xiao,Aoru Ren et al.
Xiaoyan Qiu et al.
To improve the isolation efficiency of parthenogenetic embryonic stem cells (pESCs) in mice, it is necessary to optimize the method to increase in vitro developmental competence of mice parthenogenetic blastocysts. Therefore, this study aim...
Reprogramming of Pluripotency-Specific microRNA Signatures Is Not Essential to Generate Inducible Pluripotent Stem Cells [0.03%]
诱导多能干细胞的重编程无需多能性特异性的microRNAs参与
Maria Skamagki,Cheng Zhang,Zhong Liu et al.
Maria Skamagki et al.
SQLE Promotes Differentiation and Apoptosis of Bovine Skeletal Muscle-Derived Mesenchymal Stem Cells [0.03%]
SQLE促进牛骨骼肌源性间充质干细胞的分化和凋亡
Ruimen Zhang,Yanfei Deng,Qiao Lv et al.
Ruimen Zhang et al.
In this study, Squalene epoxidase (SQLE) overexpression vector was transfected into bovine skeletal muscle-derived mesenchymal stem/stromal cells (MSCs) to study the molecular mechanism of SQLE regulating meat quality through myogenesis. We...
Timing of the First Cleavage and In Vitro Developmental Potential of Bovine Somatic Cell Nuclear Transfer Embryos Activated by Different Protocols [0.03%]
不同的激活方法对体细胞核移植胚胎第一次卵裂时间及发育的影响
Satoshi Akagi,Shinnosuke Tamura,Kazutsugu Matsukawa
Satoshi Akagi
The objective of this study was to examine the relationship between the timing of the first cleavage and in vitro development of somatic cell nuclear transfer (SCNT) embryos produced by different activation protocols. SCNT embryos were acti...