Metabolic Enhancement of Glycolysis and Mitochondrial Respiration Are Essential for Neuronal Differentiation [0.03%]
神经分化中糖酵解和线粒体呼吸的代谢增强作用是必要的
Ding Li,Zhexu Ding,Manjin Gui et al.
Ding Li et al.
Metabolic reactions provide energy and metabolic substance for cell function. It was recently shown that metabolic reprogramming is a key regulator of cell pluripotency and differentiation. Although many evidences point to a metabolic "swit...
Distinctive Cellular Transcriptomic Signature and MicroRNA Cargo of Extracellular Vesicles of Horse Adipose and Endometrial Mesenchymal Stem Cells from the Same Donors [0.03%]
来自同一供体马脂肪和子宫间充质干细胞的细胞外囊泡独特的转录组特征及microRNA货物分析
Felipe Navarrete,Yat Sen Wong,Joel Cabezas et al.
Felipe Navarrete et al.
Equine endometrial and adipose mesenchymal stem cells (eMSCs and aMSCs, respectively) were isolated from the same donors of thoroughbred mares. The cells displayed characteristic features of MSCs, including trilineage mesodermal and also ne...
Effects of Dimethyl Sulfoxide on the Pluripotency and Differentiation Capacity of Mouse Embryonic Stem Cells [0.03%]
二甲基亚砜对小鼠胚胎干细胞多能性和分化能力的影响
Jun-Koo Yi,Song Park,Jae-Jung Ha et al.
Jun-Koo Yi et al.
Mouse embryonic stem cells (mESCs) go through self-renewal in the existence of the cytokine leukemia inhibitory factor (LIF). LIF is added to the mouse stem cells culture medium, and its removal results in fast differentiation. Dimethyl sul...
The Extracts of Human Fetal Brain Induce the Differentiation of Human Umbilical Cord Mesenchymal Stem Cells into Dopaminergic Neuron Containing Cells [0.03%]
人胎儿脑提取物能够诱导人脐带间充质干细胞分化为多巴胺能神经细胞
Yonghai Li,Junzheng Yang,Meng Li et al.
Yonghai Li et al.
Mesenchymal stem cells (MSCs) have the potential to differentiate into neuron-like cells, which may provide a new strategy for the clinical treatment of neurodegenerative diseases such as Parkinson's disease (PD). However, the application o...
Bone Marrow Mesenchymal Stem Cells Promote the Stemness of Hypopharyngeal Cancer Cells [0.03%]
骨髓间充质干细胞促进下咽癌细胞的干性特征
Danyang Li,Yiming Liu,Jinyan Qi et al.
Danyang Li et al.
A study was to investigate the regulation of bone marrow mesenchymal stem cells (BMSCs) on the stemness of hypopharyngeal cancer cells (FaDu cells). Green fluorescent protein-labeled FaDu cells were cocultured with BMSCs and then were isola...
Effect of Additional Cytoplasm of Cloned Embryo on In Vitro Developmental Competence and Reprogramming Efficiency in Mice [0.03%]
克隆胚胎额外细胞质对小鼠体外发育能力和重编程效率的影响
Seok-Hwan Song,Seon-Hwa Oh,Lianguang Xu et al.
Seok-Hwan Song et al.
Somatic cell nuclear transfer (SCNT) is an important technique for biological science research. Cytoplasm injection cloning technology (CICT) was developed to improve the reprogramming efficiency as well as to overcome the limitations of SC...
Comparative Study
Cellular reprogramming. 2020 Oct;22(5):236-243. DOI:10.1089/cell.2020.0022 2020
Reprogramming Prostate Cancer Cells into Induced Pluripotent Stem Cells: a Promising Model of Prostate Cancer Stem Cell Research [0.03%]
将前列腺癌细胞重编程为诱导多能干细胞：一种有前景的前列腺癌干细 胞研究模型
Yiming Zhang,Binshen Chen,Peng Xu et al.
Yiming Zhang et al.
Prostate cancer stem cells (PrCSCs) are responsible for the development of castration-resistant disease and are associated with poor outcomes; however, the origin of PrCSCs is still not known due to the lack of a suitable model. In the curr...
Érika Almeida Praxedes,Fabiana Fernandes Bressan,Alexsandra Fernandes Pereira
Érika Almeida Praxedes
Cellular reprogramming mainly involves induction of reactivation of genes responsible for nuclear plasticity, a process that can be performed in vitro through production of cloned embryos by somatic cell nuclear transfer or by induction of ...
The Effect of L-Carnitine Additive During In Vitro Maturation on the Vitrification of Pig Oocytes [0.03%]
L-肉毒碱添加对体外培养猪卵母细胞玻璃化冷冻效应的研究
Hongxia Xu,Chao Jia,Wenxiu Cheng et al.
Hongxia Xu et al.
Cryopreservation of oocytes/embryos is an important technique for genetic resources; however, the success of vitrification in pig oocytes remained at a relatively lower level due to the high content of lipid droplets (LDs). Considering the ...
Activation of Wnt/β-Catenin Signaling Pathway Enhances the Derivation of Buffalo (Bubalus bubalis) Embryonic Stem Cell-Like Cells [0.03%]
Wnt/β-连环蛋白信号通路的激活可促进水 buffalo 胚胎干细胞样细胞的诱导分化
Yanfei Deng,Yanping Lao,Qiuyan Ruan et al.
Yanfei Deng et al.
Wnt/β-Catenin signaling pathway plays an important role in maintaining self-renewal and pluripotency of human and mouse embryonic stem cells (ESCs). Activation of Wnt/β-Catenin signaling pathway by glycogen synthase kinase-3 (GSK3) inhibi...