Filipe Pereira
Filipe Pereira
Porcine OCT4 Reporter System Can Monitor Species-Specific Pluripotency During Somatic Cell Reprogramming [0.03%]
猪OCT4报告系统可在体细胞重编程过程中监测物种特异性的多能性
Seung-Hun Kim,Kwang-Hwan Choi,Mingyun Lee et al.
Seung-Hun Kim et al.
This study examined the activity and function of pig OCT4 enhancer in porcine reprogramming cells. Dual fluorescent protein reporter systems controlled by the upstream regulatory region of OCT4, which is one of the master regulators for plu...
Two Small Molecule Inhibitors Promote Reprogramming of Guangxi Bama Mini-Pig Mesenchymal Stem Cells Into Naive-Like State Induced Pluripotent Stem Cells [0.03%]
两种小分子化合物促进广西巴马小型猪间充质干细胞向原始态诱导多能干细胞重编程
Feng Chen,Deshun Shi,Lingxiu Zou et al.
Feng Chen et al.
Past researches have shown that pluripotency maintenance of naive and primed-state pluripotent stem cells (PSCs) depends on different signaling pathways, and naive-state PSCs possess the ability to produce chimeras when they are introduced ...
Soo-Been Jeon,Bo-Gyeong Seo,Sang-Ki Baek et al.
Soo-Been Jeon et al.
Pluripotent stem cells (PSCs) have the ability of self-renewal that can retain the characteristics of the mother cell, and of pluripotency that can differentiate into several body types. PSCs typically include embryonic stem cells (ESCs) de...
Muhmmad Atif,Abdullah Alsrhani,Farrah Naz et al.
Muhmmad Atif et al.
Adenosine plays a significant role in neurotransmission process by controlling the blood pressure, while adenosine triphosphate (ATP) acts as a neuromodulator and neurotransmitter and by activation of P2 receptors, regulates the contractili...
Investigating Markers of Reprogramming Potential in Somatic Cell Lines Derived from Matched Donors [0.03%]
来源于配对供体的体细胞系中重编程标记物的研究
Tahmineh Toorani,Paula M Mackie,Gabriela F Mastromonaco
Tahmineh Toorani
Somatic cell biobanking and related technologies, somatic cell nuclear transfer (SCNT), and induction of pluripotent stem cells offer significant promise for wildlife conservation, but have yet to achieve optimal success. Inefficiency and v...
The Effect of EZH2 Inhibition through DZNep on Epithelial-Mesenchymal Transition Mechanism [0.03%]
DZNep通过EZH2抑制上皮间质转化机制的作用研究
Merve Özel,Eser Kilic,Mevlüt Baskol et al.
Merve Özel et al.
Although the molecular pathogenesis of hepatocellular carcinoma (HCC) is uncertain, it is known that the epithelial-mesenchymal transition (EMT) mechanism and epigenetic changes have an important role. This study was focused on evaluating t...
Transforming Growth Factor-β1 Enhances Mesenchymal Characteristics of Buffalo (Bubalus bubalis) Bone Marrow-Derived Mesenchymal Stem Cells [0.03%]
TGF-β1通过激活ERK信号促进水 buffalo骨髓间充质干细胞向间充质方向分化
Jun Zhang,Xiling Qin,Yanfei Deng et al.
Jun Zhang et al.
Bone marrow-derived mesenchymal stem cells (BMSCs) from livestock are valuable resources for animal reproduction and veterinary therapeutics. Previous studies have shown that BMSCs were prone to malignant transformation of mesenchymal-to-ep...
BMP9 Can Induce Schwann Cells Expressing Simian Virus 40 T Antigen to Differentiate into Fat and Bone In Vivo and In Vitro [0.03%]
BMP9可诱导SV40Tag阳性雪旺细胞向骨和脂肪分化
Rui-Fang Li,Guo-Xin Nan,Dan Wang et al.
Rui-Fang Li et al.
In our previous study, we constructed Schwann cells (SCs) that stably express Simian virus 40 T antigen (SV40T-SCs). SV40T-SCs functions and markers are similar to those of neural crest cells. There we used bone morphogenetic protein 9 (BMP...
Aberrant Epigenetic Reprogramming in the First Cell Cycle of Bovine Somatic Cell Nuclear Transfer Embryos [0.03%]
牛体细胞克隆胚胎第一次细胞周期中表观遗传重编程异常研究
LiJun Wang,LiXiu Liu,YongSheng Wang et al.
LiJun Wang et al.
Zygotic epigenetic reprogramming is the major initial event in embryo development to acquire a totipotent potential. However, the patterns of epigenetic modifications in bovine zygote were not well clarified, especially in the first cell cy...