Comprehensive immune profiling reveals IFN-γ signaling in T cells mediates parasite phagocytosis in a rodent malaria model [0.03%]
综合免疫谱分析发现,在啮齿动物疟疾模型中T细胞的IFN-γ信号传导介导寄生虫吞噬作用
Sha-Sha Chen,Qingxin Yang,Yu Zhong et al.
Sha-Sha Chen et al.
Pulmonary manifestation in malaria can be life-threatening. Using a rodent malaria model and comprehensive transcriptomics analyses to illustrate the immune landscape of malaria-associated lung pathology, we identified that IFN-γ signaling...
Genomic insights into a clade-specific Candida tropicalis lineage with resistance to azoles and immune evasion traits [0.03%]
对具有耐唑类和免疫逃避特征的热带假丝酵母特有谱系进行基因组学分析
Kusum Jain,Nityendra Shukla,Amtoj Kaur et al.
Kusum Jain et al.
Candida tropicalis is a leading cause of invasive candidiasis in the Asia-Pacific region with reported crude mortality rates exceeding 50%. The rising prevalence of azole-resistant strains presents a significant clinical challenge. We analy...
Antibiotic-induced microbiota disruption impairs neutrophil-mediated immunity to respiratory Aspergillus fumigatus infection in mice [0.03%]
抗生素引起的微生物群紊乱会损害小鼠呼吸道烟曲霉感染的中性粒细胞介导免疫反应
Mariano A Aufiero,Tobias M Hohl
Mariano A Aufiero
Aspergillus fumigatus is an ubiquitous environmental mold that forms airborne conidia and can cause life-threatening infections in immunocompromised individuals. Invasive aspergillosis occurs in patients with quantitative or qualitative neu...
Parasitic connections: a patescibacterial epibiont, its methylotrophic gammaproteobacterial host, and their phages [0.03%]
寄生连接:其甲基营养型γ-变形细菌宿主及其噬菌体的粘附类细菌外共生体
Feriel Bouderka,Purificación López-García,Philippe Deschamps et al.
Feriel Bouderka et al.
Patescibacteriota form a very diverse and widely distributed phylum of small bacteria inferred to have an episymbiotic lifestyle. However, the prevalence of this lifestyle within the phylum and its host specificity remain poorly known due t...
mGem: Progress on the development of conjugate vaccines for Cryptococcus neoformans infections [0.03%]
mGem:新型隐球菌感染的结合疫苗开发进展
Piotr R Stempinski,Samuel Rodrigues Dos Santos Junior,Arturo Casadevall
Piotr R Stempinski
Cryptococcus neoformans is an important fungal pathogen that causes cryptococcosis, a life-threatening disease predominantly affecting immunocompromised individuals. Current estimates suggest that cryptococcosis is responsible for over 150,...
Guanylate-binding proteins balance iNOS/Arg-1 in myeloid cells during L. major infection and promote host defense to infection [0.03%]
鸟苷酸结合蛋白在利什曼原虫感染过程中平衡髓系细胞中的iNOS/Arg-1并促进宿主抗感染免疫反应
Lucy Fry,Het Adhvaryu,Hayden Roys et al.
Lucy Fry et al.
Cutaneous leishmaniasis (CL) is a debilitating neglected tropical disease characterized by lesions that can range from self-healing to permanent disfiguration. A predominant Th1 response, which stimulates IFN-γ production, is crucial for p...
Analysis and engineering of quorum sensing-based communications between bacteria and fungi [0.03%]
基于群体感应的细菌和真菌之间信号交流的分析与工程化
Yongsheng Zhou,Lingjin Tang,Danlei Chen et al.
Yongsheng Zhou et al.
Bacteria and fungi ubiquitously coexist, with their interactions critically influencing human health and industrial processes. Quorum sensing (QS) is a core regulatory mechanism that enables density-dependent coordination and phenotypic res...
Will top-ranked scientific publications become the preserve of "rich" groups? ASM editorial policy [0.03%]
高居排名的科学出版物会成为“富人”的专属吗?ASM编辑政策
Juan Carlos Argüelles
Juan Carlos Argüelles
African swine fever virus hijacks lipolysis induced by chaperone-mediated autophagy to upregulate fatty acid β-oxidation and promote viral replication [0.03%]
非洲猪瘟病毒劫持伴胞介导的自噬诱导的脂解以上调脂肪酸β氧化和促进病毒复制
Xing Yang,Xin Xiong,Huanan Liu et al.
Xing Yang et al.
Lipid metabolism plays a crucial role in cellular signal transduction, affects the structural integrity of cell membranes, and regulates energy metabolism. However, various viruses, including African swine fever virus (ASFV), usurp lipid me...
Erratum for Yuan et al., "Case-control and genomic epidemiology characterization of SARS-CoV-2 breakthrough infections during Delta-to-Omicron transition" [0.03%]
袁等人关于《德尔塔变异株向奥密克戎变异株过渡期间新冠病毒感染的病例对照和基因组流行病学特征》一文的勘误通知
Erin Yuan,Chelsea L Hansen,Sana Tamim et al.
Erin Yuan et al.
Published Erratum
mBio. 2026 Mar 9:e0045526. DOI:10.1128/mbio.00455-26 2026