LncRNA6470/ace-miR-750-y axis modulates AcPP2A gene, immune response and survival of eastern honey bee larvae during fungal infection [0.03%]
长链非编码RNA6470/ace-miR-750-y轴在真菌感染东方蜜蜂幼虫AcPP2A基因、免疫反应和存活中的调控作用
Xiaoxue Fan,Kaiyao Zhang,Yunzhen Yang et al.
Xiaoxue Fan et al.
Chalkbrood, a destructive larval disease caused by the fungal pathogen Ascosphaera apis, causes substantial losses in apiculture. Although host-pathogen interactions in Apis mellifera larvae infected with A. apis have been investigated, imm...
Global translational reprogramming in Trichophyton mentagrophytes-infected keratinocytes [0.03%]
表皮癣菌感染角质形成细胞中的全局转录重编程
Jun Wan,Yuhong Zhang,Yangxu Deng et al.
Jun Wan et al.
Dermatophytosis afflicts approximately 25% of the global population, representing a critical public health burden. Trichophyton mentagrophytes (T. mentagrophytes), a predominant zoonotic dermatophyte, is a significant contributor to disease...
Lactylation in influenza a virus infection: Current evidence, knowledge gaps, and future perspectives [0.03%]
流感病毒乳酰化的研究现状、知识空白及未来前景
Yu-Mei Chen Yan,Zhijun Li,Haiyan He et al.
Yu-Mei Chen Yan et al.
Influenza A virus (IAV) is a major respiratory pathogen causing seasonal epidemics and pandemics, posing serious threats to public health and livestock. The high mutation rate of IAV leads to vaccine mismatches and drug-resistant variants, ...
The Mcu1 mitochondrial protein coordinates TCA cycle enzymes to modulate phenotypic switching and commensalism in Candida albicans [0.03%]
麦独孤1线粒体蛋白通过协调芽生酒酵母中的三羧酸循环酶来调节表型转换和共生关系
Mingyang Ma,Ming Xu,Shuyun Guan et al.
Mingyang Ma et al.
Candida albicans is a common resident of humans that colonizes multiple sites in the human body, such as the gut, in healthy individuals. In immunocompromised hosts, however, it can switch to a pathogenic state and cause infections. The mol...
Trinh Phan-Canh,Saskia Seiser,Manju Chauhan et al.
Trinh Phan-Canh et al.
Candida auris (Candidozyma auris) has emerged as a multidrug‑resistant human fungal pathogen that causes infections of high morbidity and mortality. Notably, it exhibits a unique ability to grow and persist on human skin, thus leading to e...
VPS33A and VPS18 orchestrate porcine epidemic diarrhea virus replication by modulating autophagic flux [0.03%]
VPS33A和VPS18通过调节自噬流来调控猪流行性腹泻病毒的复制
Liang Guo,Jin Li,Zhuolin Hao et al.
Liang Guo et al.
Completion of autophagy through autophagosome-lysosome fusion represents a critical regulatory checkpoint that is frequently manipulated during viral infection, however, how coronaviruses exploit this terminal step remains incompletely unde...
Host-Orf virus interactions: A comprehensive review of pathogenesis and immune evasion mechanisms [0.03%]
orb病毒互作：发病机制与免疫逃逸机制综述
Feng Pang,Shaobo Liang,Jingjin Hu et al.
Feng Pang et al.
Orf virus (ORFV), a zoonotic parapoxvirus, causes contagious ecthyma in small ruminants. It is uniquely characterized by its ability to cause proliferative, self-resolving skin lesions and systematically evade host immunity to cause repeate...
Cryptosporidium parvum CpARO marks rhoptry envelope remnants associated with feeder organelle formation [0.03%]
Cryptosporidium parvum CpARO 标记与营养器官形成相关的顶体包膜残余物
Ying Zhang,Chenchen Wang,Xin Zhao et al.
Ying Zhang et al.
Apicomplexans encode a single armadillo repeat-only (ARO) protein, exemplified by TgARO and PfARO, that anchors to the rhoptry envelope through N-terminal acylation and supports rhoptry positioning through interaction with an ARO-interactin...
Dual population-level processes contribute to polyclonal ceftiofur heteroresistance in swine-derived Escherichia coli [0.03%]
猪源大肠杆菌头孢噻呋多克隆异质性耐药的产生是两种群体水平过程共同作用的结果
Junling Cui,Zhongyi Fang,Qiuru Chen et al.
Junling Cui et al.
Antimicrobial resistance represents a major global health challenge. In veterinary medicine, ceftiofur is widely used to treat bacterial infections, yet its efficacy has been increasingly compromised by the dissemination of extended-spectru...
Cross-host transmission of Riemerella anatipestifer to chickens: Genomic evolution and identification of the novel vapX-like- vapD toxin-antitoxin system [0.03%]
鸡型败血支原体对家禽的跨宿主传播：基因组进化及新型vapX-like-vapD 毒素-抗毒素系统的鉴定
Fanrun Meng,Ruiqi Li,Yancheng Yu et al.
Fanrun Meng et al.
Riemerella anatipestifer (R. anatipestifer), a well-known waterfowl pathogen, increasingly threatens Chinese poultry by spreading to chickens. The genetic differentiation and host adaptation following cross-host transmission remain unclear....