LncRNA-CFTBS enhances Mycobacterium tuberculosis survival in macrophages by modulating ferroptosis through the miR-515-5p/miR-519e-5p/SAT1 axis [0.03%]
长链非编码RNA-CFTBS通过调节铁死亡途径中的miR-515-5p/miR-519e-5p/SAT1轴增强巨噬细胞中结核分枝杆菌的存活
Yuxin Li,Yajuan Bai,Chunyu Hei et al.
Yuxin Li et al.
Tuberculosis (TB) remains one of the primary global causes of death and poses substantial public health challenges. The intracellular survival of Mycobacterium tuberculosis (M.tb) can be influenced by ferroptosis; however, how lipid peroxid...
Microbiological control for mosquito larvae: Current progress and applications [0.03%]
蚊子幼虫微生物控制研究：进展与应用展望
Geng Hong,Lu Yu,Hengqing Ji et al.
Geng Hong et al.
Entomopathogenic microorganisms, including bacteria, fungi, and viruses, present a promising approach to mosquito control due to their high efficacy, species specificity, and environmental safety. Targeting larval stages is a strategic comp...
Mucosal passive immunization with monoclonal antibodies targeting Candidalysin and Hyr proteins attenuates vaginal candidiasis in mice [0.03%]
针对白念珠菌细胞壁关键毒性分子的单克隆抗体用于粘膜免疫被动保护，减轻小鼠阴道念珠菌病
Julie Auffray,Nicolas Biteau,Anne Cayrel et al.
Julie Auffray et al.
Vulvovaginal candidiasis (VVC) is a prevalent fungal infection primarily caused by the opportunistic pathogen Candida albicans. Among women affected by VVC, up to 8% experience more than four episodes per year, regarded as recurrent vulvova...
Interaction with amoeba drives virulence-associated phenotypes in the Candida haemulonii complex [0.03%]
与变形虫的互作引起汉穆尼念珠菌复合群的毒力表型变化
Artid Amsri,Kritsada Pruksaphon,Patcharin Thammasit et al.
Artid Amsri et al.
Predation by amoebae can induce adaptive traits in microorganisms, enhancing their resilience and pathogenic potential. This study investigated whether interaction with Acanthamoeba castellanii modulates the virulence of environmental fungi...
Manganese homeostasis modulates glucan and chitin unmasking in the opportunistic yeast Candida albicans [0.03%]
锰代谢稳态调节机会致病酵母白念珠菌多糖和几丁质的解藏作用
Manon Henry,Maria Khouas,Gabriel Théberge-Julien et al.
Manon Henry et al.
Candida albicans is a commensal fungus and also the most prevalent human fungal pathogen. The ability of this opportunistic yeast to acquire and maintain homeostatic levels of manganese (Mn), particularly in the metal-limited host environme...
Iron metabolism contributes to virulence by enhancing serum resistance in the emerging high-risk clone ST15 CRKP [0.03%]
铁代谢通过增强新出现的高风险克隆ST15 CRKP的血清抵抗性从而促其毒力形成
Jingjing Chen,Hailong Li,Fushun Li et al.
Jingjing Chen et al.
ST15 has become one of the most common sequence types of carbapenem-resistant Klebsiella pneumoniae (CRKP) in China; however, the characteristics of ST15 CRKP remains elusive. This study included a total of 72 unique CRKP isolates, comprisi...
Antifungal mechanism of ketone volatile organic compounds against Pseudogymnoascus destructans [0.03%]
酮类挥发性有机化合物的抗真菌作用机制研究——以蝙蝠冬季滞留 syndrome 真菌为目标菌株
Yaping Lu,Yue Zhu,Long Huang et al.
Yaping Lu et al.
Ketone volatile organic compounds have demonstrated favorable inhibitory activity against a wide range of pathogenic fungi, including Pseudogymnoascus destructans (Pd), the lethal pathogenic fungus responsible for white-nose syndrome in bat...
Reduction of extracellular vimentin in blood provides protection against SARS-CoV-2 infection [0.03%]
血液中降解细胞外波形蛋白可预防SARS-CoV-2感染
Hae-Mi Kim,Mingda Wang,Chongkai Zhai et al.
Hae-Mi Kim et al.
In vitro studies have repeatedly showed that extracellular vimentin (eVIM) promotes the penetration of viruses by acting as an adhesion factor, suggesting that reducing eVIM density in the blood could be an effective approach to treat viral...
Calcium transport systems as virulence determinants: Mechanistic insights into fungal pathogenicity and antifungal resistance [0.03%]
钙转运系统作为致病因素：真菌致病性和抗真菌耐药性的机制研究见解
Ndeshifwaya Rogathe Lukumay,Yitong Li,Hongchen Wang et al.
Ndeshifwaya Rogathe Lukumay et al.
This review examines the molecular mechanisms through which calcium transport proteins modulate virulence and drug resistance in human pathogenic fungi, synthesizing recent advances in calcium homeostasis research. Emerging evidence from ca...
Correction [0.03%]
改正
Published Erratum
Virulence. 2025 Dec;16(1):2566547. DOI:10.1080/21505594.2025.2566547 2025