Fungal infections in diabetic foot and other dermatoses: new species and clinical outcomes [0.03%]
糖尿病足部真菌感染及其他皮肤病原新种及临床疗效研究
Jing-Zu Sun,Qiu-Hong Yan,Shan Li et al.
Jing-Zu Sun et al.
Oxymatrine ameliorates Malassezia overgrowth-induced psoriasis in vivo and in vitro by inhibiting the biofilm formation and inflammation [0.03%]
氧化.matrine通过抑制生物膜的形成和炎症来改善马拉色菌过度生长引起的银屑病
Miao-Miao Liu,Jie Bai,Zi-Ye Tian et al.
Miao-Miao Liu et al.
The basidiomycetous yeast genus Malassezia is involved in the exacerbation of psoriatic lesions. Oxymatrine (OMT), a quinoline alkaloid derived from Sophora flavescens, exhibits diverse pharmacological properties, including anti-inflammator...
Pyruvate decarboxylase and its lysine succinylation contribute to the development and metabolite biosynthesis in pathogenic fungus Aspergillus flavus [0.03%]
丙酮酸脱羧酶及其赖氨酸琥珀酰化修饰参与黄曲霉的发病过程及代谢产物生物合成
Guoqi Li,Elisabeth Tumukunde,Yuanyuan Chen et al.
Guoqi Li et al.
This study evaluates the effects of pyruvate decarboxylase and its lysine succinylation (Ksucc) on the development of Aspergillus flavus and the production of secondary metabolites. Mutant strains, including the knockout (∆pdc1), pdc1 poin...
TPO1-based polyamines transport contributes to pathogenicity of sugarcane smut fungus [0.03%]
TPO1介导的聚胺运输参与甘蔗黑穗病菌致病性
Kai Yin,Zhijian Hu,Chuyan Chen et al.
Kai Yin et al.
The basidiomycete Sporisorium scitamineum causes sugarcane smut disease, leading to a significant impairment in the quality and yield of sugarcane. Polyamines affect the intracellular redox balance, which is important for the pathogenic dev...
Minutellins E-I and daldinone L, new secondary metabolites from different species of the Hypoxylaceae (Xylariales, Ascomycota) [0.03%]
来自Hypoxylaceae（Xylariales，Ascomycota）不同种的微小霉素E-I和daladine L等次级代谢产物
Christopher Lambert,Mohammad Javad Pourmoghaddam,Esteban Charria-Girón et al.
Christopher Lambert et al.
Fungi of the family Hypoxylaceae (Xylariales, Ascomycota) are ubiquitously distributed and fulfil important ecological roles as saprobes, pathogens, and endophytes. Members of this family tend to store large amounts of secondary metabolites...
Endophytic fungi as a source of antimicrobial compounds against emerging methicillin-resistant Staphylococcus aureus [0.03%]
内生真菌作为抗新出现的耐甲氧西林金黄色葡萄球菌抗菌化合物的来源
Shefali Bansal,Mahavir Joshi,Prachi Mahajan et al.
Shefali Bansal et al.
Antimicrobial resistance (AMR) represents a critical global health threat, significantly impacting treatment outcomes, increasing mortality, and imposing economic burdens. It also hinders progress towards Sustainable Development Goal (SDG) ...
Discovery of new bianthrones and chlorinated bianthrones with cytotoxic activity against cancer cells from Penicillium hispanicum guided by HSQC-based DeepSAT [0.03%]
基于HSQC的DeepSAT指导从西班牙青霉中发现具有抗癌细胞活性的新双 анTHRONE和氯化双 anthrone化合物
Ruiyun Huo,Minhui Ji,Gaoran Liu et al.
Ruiyun Huo et al.
Three new racemic bianthrones, including two pairs of (±)-penithrones A (1) and B (2), and a chlorinated derivative (±)-penithrone C (3), along with their biogenetic precursors (4-6) were discovered from the culture extract of the mangrov...
Interplay between Shiraia and its fruiting body-associated Rhodococcus sp. No. 3 via hypocrellin A and carotenoid biosynthesis [0.03%]
通过 hypocrellin A 和类胡萝卜素生物合成互作探索 Shiraia 及其相关链霉菌（红球菌）的相互关系
Li Ping Zheng,Qun Yan Huang,Xin Ping Li et al.
Li Ping Zheng et al.
Hypocrellin A (HA), a bioactive perylenequinone from Shiraia fruiting bodies, serves as an efficient photodynamic therapy photosensitiser. While these fruiting bodies harbour diverse bacteria, host-microbe functional interactions remain poo...
Taxonomic contributions to Pleosporales and Kirschsteiniotheliales from the Xizang Autonomous Region, China [0.03%]
来源于中国西藏自治区的丝核菌目和科尔氏薄壁孢目分类学贡献
Shu-Cheng He,Kevin D Hyde,Ruvishika S Jayawardena et al.
Shu-Cheng He et al.
The Xizang Autonomous Region, China, is a key ecological security barrier, renowned for its rich biodiversity and unique resources. It supports diverse life forms, including fungi, which are vital for ecological balance and the restoration ...
Redox engineering of thermophilic fungus Myceliophthora thermophila enhances production of L‑malic acid by consolidated bioprocessing [0.03%]
热纤亚麻锈霉菌的红ox工程通过联合生物加工提高L-苹果酸产量
Yuying Zhang,Rui Fan,Taju Wu et al.
Yuying Zhang et al.
Consolidated bioprocessing (CBP) is a promising strategy for low-cost malic acid production from plant biomass. In this study, we report a comprehensive redox engineering strategy to redirect reducing equivalents towards the reductive trica...