The α-glucosidase II MaGls2 governs virulence and stress tolerance in Metarhizium acridum by maintaining cell wall architecture [0.03%]
α-葡萄糖苷酶II MaGls2通过维持细胞壁结构调控Metarhizium acridum的致病性和应激耐受性
Yue Zhang,Yunxiao Luo,Xiaoyu Liu et al.
Yue Zhang et al.
In pathogenic fungi, N-glycosylated cell wall proteins serve as initial contact points during interactions with host. In the process of protein N-glycosylation, N-linked glycans are processed by α-glucosidases I (Gls1) and II (Gls2) to tri...
New phenolic bisabolane sesquiterpenoids discovered from the marine-derived fungus Aspergillus sydowii assisted by molecular networking and SMART strategies [0.03%]
结合分子网络和SMART策略发现由海洋来源真菌Aspergillus sydowii产生的新的菲醌类倍半萜素类化合物
Baodan Zhang,Meiyan Bao,Ling Liu
Baodan Zhang
Three previously undescribed phenolic bisabolane sesquiterpenoids (PBS) including a pair of new enantiomers (±)-aspersydonol A (1a/1b) and aspersydonol B (2), along with 12 known analogs (3-14) were isolated from the marine-associated fung...
Molecular mechanisms underlying the inhibition of Sparassis latifolia mycelial growth by cycloleucine: a comprehensive transcriptomic and m6A methylome analysis [0.03%]
宽边齿瑚菌胞外多糖抑制孢粉素侧耳菌丝生长的分子机制：全面转录组与m6A甲基组分析
Chi Yang,Dandan Wu,Donglai Xiao et al.
Chi Yang et al.
Cycloleucine, a non-proteinogenic amino acid, has been identified as a potent inhibitor of fungal growth; however, its molecular mechanisms of action against the edible mushroom Sparassis latifolia remain inadequately understood. In this st...
Bioactive eremophilane meroterpenoids produced by the soil fungus Stchigelomyces brunnescens gen. et comb. nov [0.03%]
一种土壤真菌Stchigelomyces brunnescens产生的生物活性厄美菲兰倍半萜薁类化合物
Lisha Zhu,Margarita Hernández-Restrepo,Manuela Agudelo-Restrepo et al.
Lisha Zhu et al.
The emergence of antimicrobial resistance has created an urgent demand for novel antibiotics. Fungi in the order Sordariales represent a rich source of chemically diverse and bioactive secondary metabolites. However, many taxa within this o...
Biogeography and species diversity of freshwater Savoryellomycetidae (Sordariomycetes) fungi [0.03%]
淡水Savoryellomycetidae(Sordariomycetes)真菌的生物地理学和物种多样性
Wen-Peng Wang,Hong-Wei Shen,Dan-Feng Bao et al.
Wen-Peng Wang et al.
The subclass Savoryellomycetidae (Sordariomycetes, Ascomycota) primarily consists of fungal saprobes on decayed wood from freshwater habitats. They are widely distributed worldwide with a higher diversity in Asia. This study comprehensively...
Integrating novel culturing and culture-independent methods to unveil soil fungal dark matter, functional guilds and environmental drivers across Robinson Ridge, East Antarctica [0.03%]
结合培养和非培养方法揭示罗宾逊山土壤真菌“暗物质”、功能群及其环境驱动因素
Nicole Benaud,Nathali Machado de Lima,Sin Yin Wong et al.
Nicole Benaud et al.
Global fungal diversity is estimated to range in the millions, yet it remains severely underexplored, especially in extreme environments. Fewer than 5% of species have been officially identified and characterised. Estimates suggest that 70%...
Metabolites associated with endophytic fungi in agarwood: fungal compounds and host metabolites triggered by fungi [0.03%]
沉香内生真菌相关次生代谢产物：真菌化合物和宿主植物的诱导代谢物
Tian-Jiao Ma,Yun Yang
Tian-Jiao Ma
Agarwood is a scarce and highly prized resinous material, revered for its medicinal properties and distinctive aroma profile. Traditional medical manuscripts meticulously document their application in pain relief and the alleviation of gast...
Yuanyuan Xia,Lirong Zhu,Haitao Chen et al.
Yuanyuan Xia et al.
Heterotrimeric G proteins (G proteins) are important components of G protein signalling pathways, play an important role in cellular activities, and are composed mainly of three subunits: Gα, Gβ, and Gγ. At present, G proteins have been ...
Ten previously undescribed norsesquiterpenoids from the fungus Marasmiellus candidus and their anti-inflammatory activities [0.03%]
来自真菌Marasmiellus candidus的10种新的抗炎活性鼻拉酸三萜类化合物
Lan Yao,Shiyu Li,Jinxiu Zhang et al.
Lan Yao et al.
In this study, ten undescribed norsesquiterpenoids, named marasmiellactones R-U (1-4) and marasmielolic acids A-F (5-10), were isolated from the cultures of the fungus Marasmiellus candidus. Their planar structures were characterised using ...
The molecular revolution in fungal diagnostics: bridging gaps across clinical, agricultural, and environmental mycology [0.03%]
分子诊断革命：临床、农业和环境真菌学的桥梁工程
Youssuf A Gherbawy,Helal Al-Harthi,Eman El-Dawy et al.
Youssuf A Gherbawy et al.
Fungi play essential roles in human health, agriculture, and ecosystems, yet their diversity has long been underestimated due to reliance on morphology and culture. Molecular innovations-DNA barcoding, multilocus and whole-genome sequencing...