Shruti Bagla,Alan A Dombkowski
Shruti Bagla
A rapidly growing body of evidence supports the premise that neuroinflammation plays an important role in initiating and sustaining seizures in a range of pediatric epilepsies. Clinical and experimental evidence indicate that neuroinflammat...
SCN2A-Related Early-Onset Epileptic Encephalopathy Responsive to Phenobarbital [0.03%]
苯巴比妥治疗有效的SCN2A相关早期发作性癫痫性脑病
Fiona M Baumer,Jurriaan M Peters,Christelle M El Achkar et al.
Fiona M Baumer et al.
Voltage-gated sodium channels (Nav) are critical regulators of neuronal excitability. Genes for the α-subunits of three sodium channel subtypes-SCN1A, SCN2A, and SCN3A-are all located on chromosome 2q24. A full-term boy with an unremarkabl...
Simultaneous Electroencephalography and Functional Magnetic Resonance Imaging and the Identification of Epileptic Networks in Children [0.03%]
儿童癫痫网络的识别过程中的脑电图及功能磁共振成像的联合应用
Thomas C Maloney,Jeffrey R Tenney,Jerzy P Szaflarski et al.
Thomas C Maloney et al.
EEG/fMRI takes advantage of the high temporal resolution of EEG in combination with the high spatial resolution of fMRI. These features make it particularly applicable to the study of epilepsy in which the event duration (e.g., interictal e...
Disorders of GABA metabolism: SSADH and GABA-transaminase deficiencies [0.03%]
_gamma-氨基丁酸代谢紊乱：SSADH和_GABA转氨酶缺乏症
Mahsa Parviz,Kara Vogel,K Michael Gibson et al.
Mahsa Parviz et al.
Clinical disorders known to affect inherited gamma-amino butyric acid (GABA) metabolism are autosomal recessively inherited succinic semialdehyde dehydrogenase and GABA-transaminase deficiency. The clinical presentation of succinic semialde...
Leaving tissue associated with infrequent intracranial EEG seizure onsets is compatible with post-operative seizure freedom [0.03%]
保留偶发性颅内癫痫发作相关的组织与术后无发作相容性强
Cyrus Huang,Eric D Marsh,Daniela M Ziskind et al.
Cyrus Huang et al.
Identify seizure onset electrodes that need to be resected for seizure freedom in children undergoing intracranial electroencephalography recording for treatment of medically refractory epilepsy. All children undergoing intracranial electro...