RNA editing generates mRNA isoforms with distinct stabilities that may expand the thermal tolerance of mRNA and proteins in Mytilus species [0.03%]
甲壳动物中的RNA编辑生成具有不同稳定性的mRNA异构体并可能扩大其耐热范围
Ming-Ling Liao,Ya-Jie Zhu,Xiao-Lu Zhu et al.
Ming-Ling Liao et al.
Ectothermic organisms may expand their thermal tolerance by producing multiple protein isoforms with differing thermal sensitivities. While such isoforms commonly originate from allelic variation at a single locus (allozymes) or from gene d...
Fu-Nong Luo,Shu-Jun Chen,Hojjat Asadollahpour Nanaei et al.
Fu-Nong Luo et al.
Coat color polymorphism in domestic animals provides a robust framework for elucidating mechanisms of species adaptation, domestication, and genomic diversity. Leiqiong cattle, a representative indicine breed from southern China, are predom...
Convergent musk biosynthesis across host and microbiota in musk deer and muskrat [0.03%]
雄麝和麝鼠中宿主与共生微生物协同合成麝香化合物
Yi-Shan Sun,Lei Zhao,Cheng-Li Zheng et al.
Yi-Shan Sun et al.
Mammalian scent glands mediate species-specific chemical communication, yet the mechanistic basis for convergent musk production remain incompletely understood. Forest musk deer and muskrat have independently evolved specialized musk-secret...
Phylogeography of a dominant desert lizard reveals the synergistic effects of topography and climate dynamics on diversification in arid eastern-Central Asia [0.03%]
主导沙漠蜥蜴的谱系地理学揭示了地形和气候动态在干旱东亚地区的协同分化效应
Abid Ali,Da-Li Chen,Tatjana N Dujsebayeva et al.
Abid Ali et al.
Comprehensive phylogeographic insights require the integration of evidence across diverse taxa, ecosystems, and geographical regions. However, our understanding of the arid biota of the vast Asian drylands remains limited. Accordingly, this...
Zhisheng Wu,Rongfeng Cui,Hanjie Li
Zhisheng Wu
Integrated single-cell transcriptomic map of pig kidney cells across various periods and anatomical sites [0.03%]
猪肾脏单细胞转录组整合图谱在各个时期和解剖部位的应用
Tian-Xiong Yao,Na Li,Lu-Sheng Huang
Tian-Xiong Yao
The kidney is essential for maintaining fluid, electrolyte, and metabolite homeostasis, and for regulating blood pressure. The pig serves as a valuable biomedical model for human renal physiology, offering insights across different physiolo...
Alterations in the salivary gland microbiota of Haemaphysalis longicornis during tick-to-host transmission of severe fever with thrombocytopenia syndrome virus [0.03%]
发热伴血小板减少综合征病毒从蜱传播到宿主过程中长角血蜱唾液腺微生物群的改变
Jingjing Chen,Chuanfei Yuan,Qiong Xu et al.
Jingjing Chen et al.
Haemaphysalis longicornis serves as the primary tick vector for severe fever with thrombocytopenia syndrome virus (SFTSV), the etiological agent responsible for severe fever with thrombocytopenia syndrome (SFTS). Understanding alterations i...
Consistency, distinction, and potential metabolic crosstalk of nitrogen mobilization-related genes in silk production and silk gland biology [0.03%]
与丝蛋白产生和丝腺生物学相关的氮转运相关基因的一致性，差异及潜在的代谢交叉谈话路线。
Mei-Yan Yi,Xu Yang,Man Wang et al.
Mei-Yan Yi et al.
The domesticated silkworm ( Bombyx mori) has evolved a highly efficient nitrogen utilization system to support silk production. The silk glands play a pleiotropic role in sequestering nitrogen resources for silk synthesis, mitigating aminoa...
Single-cell sequencing analysis reveals the essential role of the m 6A reader YTHDF1 in retinal visual function by regulating TULP1 and DHX38 translation [0.03%]
单细胞测序分析揭示m6A阅读蛋白YTHDF1通过调节TULP1和DHX38翻译在视网膜视觉功能中的重要作用
Xian-Jun Zhu,Xiao-Yan Jiang,Wen-Jing Liu et al.
Xian-Jun Zhu et al.
N6-methyladenosine (m 6A) modification of mRNA is a critical post-transcriptional regulatory mechanism that modulates mRNA metabolism and neuronal function. The m 6A reader YTHDF1 has been shown to enhance the translational efficiency of m ...
DNA methylation confers a cerebellum-specific identity in non-human primates [0.03%]
DNA甲基化赋予非人灵长类动物小脑特异性的身份特性
Xiao-Dong Liu,Chang-Cheng Ye,Yang Wang et al.
Xiao-Dong Liu et al.
Selective regulation of gene expression across distinct brain regions is crucial for establishing and maintaining subdivision identities. DNA methylation, a key regulator of gene transcription, modulates transcriptional activity through the...