Characterization of two novel knock-in mouse models of syndromic retinal ciliopathy carrying hypomorphic Sdccag8 mutations [0.03%]
携带SDCCAG8低效突变的两种新型串联综合征性视网膜纤毛病小鼠模型的表征
Zhi-Lin Ren,Hou-Bin Zhang,Lin Li et al.
Zhi-Lin Ren et al.
Mutations in serologically defined colon cancer autoantigen protein 8 ( SDCCAG8) were first identified in retinal ciliopathy families a decade ago with unknown function. To investigate the pathogenesis of SDCCAG8-associated retinal ciliopat...
Adult hippocampal neurogenesis and its impairment in Alzheimer's disease [0.03%]
成人海马神经发生及其在阿尔茨海默病中的障碍
Thomas A Kim,Michelle D Syty,Kaitlyn Wu et al.
Thomas A Kim et al.
Adult neurogenesis is the creation of new neurons which integrate into the existing neural circuit of the adult brain. Recent evidence suggests that adult hippocampal neurogenesis (AHN) persists throughout life in mammals, including humans....
Scan of the endogenous retrovirus sequences across the swine genome and survey of their copy number variation and sequence diversity among various Chinese and Western pig breeds [0.03%]
猪基因组内源性反转录病毒序列的扫描及对中国地方猪品种和西方猪品种中该序列拷贝数变异和序列多态性的考察
Jia-Qi Chen,Ming-Peng Zhang,Xin-Kai Tong et al.
Jia-Qi Chen et al.
In pig-to-human xenotransplantation, the transmission risk of porcine endogenous retroviruses (PERVs) is of great concern. However, the distribution of PERVs in pig genomes, their genetic variation among Eurasian pigs, and their evolutionar...
Novel astrovirus and paramyxovirus in Mongolian gerbils ( Meriones unguiculatus) from China [0.03%]
中国采集的仓鼠中发现新型轮状病毒和副黏液病毒
Shou-Min Nie,Juan Li,Yi-Ting Wang et al.
Shou-Min Nie et al.
A new species of the genus Typhlomys Milne-Edwards, 1877 (Rodentia: Platacanthomyidae) from Chongqing, China [0.03%]
中国重庆啮齿目盘羊亚科胎生鼠属的一种新物种
Ying-Ting Pu,Tao Wan,Rong-Hui Fan et al.
Ying-Ting Pu et al.
A new genus and species of disc-bearing Labeoninae (Teleostei: Cypriniformes) from Guangxi, China [0.03%]
中国广西盘鮋亚科一新属种（鲤形目、鲤科）
Zhi-Bang Wang,Xiao-Yong Chen,Lan-Ping Zheng
Zhi-Bang Wang
Declined fitness in larvae born from long-distance migrants of anadromous Coilia nasus in the lower reaches of the Yangtze River, China [0.03%]
长江下游刀鱼中上溯产黏性卵鱼类仔稚鱼体质下降
Yan-Fei Huang,Andrew L Rypel,Brian R Murphy et al.
Yan-Fei Huang et al.
Qiang Yang,Chuan-Min Qiao,Wei-Wei Liu et al.
Qiang Yang et al.
In an attempt to generate g.A746G substitution in the BMPR-IB gene, we unexpectedly obtained BMPR-IB homozygous knockout piglets ( BMPR-IB -/-) and heterogeneous knockout piglets with one copy of the A746G mutation ( BMPR-IB -/746G) via CRI...
Maternal sleep deprivation induces gut microbial dysbiosis and neuroinflammation in offspring rats [0.03%]
母体睡眠剥夺可诱导子代大鼠肠道菌群失调及神经炎症
Zheng-Yu Yao,Xiao-Huan Li,Li Zuo et al.
Zheng-Yu Yao et al.
Maternal sleep deprivation (MSD) is a global public health problem that affects the physical and mental development of pregnant women and their newborns. The latest research suggests that sleep deprivation (SD) disrupts the gut microbiota, ...
High-quality reference genomes of swallowtail butterflies provide insights into their coloration evolution [0.03%]
高质量的凤蝶基因组揭示其色彩进化机制
Jin-Wu He,Ru Zhang,Jie Yang et al.
Jin-Wu He et al.
Swallowtail butterflies (Papilionidae) are a historically significant butterfly group due to their colorful wing patterns, extensive morphological diversity, and phylogenetically important position as a sister group to all other butterflies...