Yan-Yuan Xiao,Qing Zhang,Fei Huang et al.
Yan-Yuan Xiao et al.
The gastrointestinal tract is essential for food digestion, nutrient absorption, waste elimination, and microbial defense. Single-cell transcriptome profiling of the intestinal tract has greatly enriched our understanding of cellular divers...
Dynamic foraging strategy adaptation to heterogeneous environments contributes to social aggregation in snub-nosed monkeys [0.03%]
动态觅食策略适应异质环境有助于金丝猴社会聚集
Lan Zhao,Sheng-Nan Ji,Xiao-Bing Du et al.
Lan Zhao et al.
The dynamics of animal social structures are heavily influenced by environmental patterns of competition and cooperation. In folivorous colobine primates, prevailing theories suggest that larger group sizes should be favored in rainforests ...
Yu-Xuan Fan,Pu-Zheng Xie,Chi Ma et al.
Yu-Xuan Fan et al.
LncRNA pol-lnc78 as a ceRNA regulates antibacterial responses via suppression of pol-miR-n199-3p-mediated SARM down-regulation in Paralichthys olivaceus [0.03%]
斑竹鱼pol-lnc78通过抑制pol-miR-n199-3p介导的SARM下调调节抗细菌反应的 ceRNA 作用机制研究
Xian-Hui Ning,Bing Han,Ye Peng et al.
Xian-Hui Ning et al.
Long non-coding RNAs (lncRNAs) function as key modulators in mammalian immunity, particularly due to their involvement in lncRNA-mediated competitive endogenous RNA (ceRNA) crosstalk. Despite their recognized significance in mammals, resear...
Full T-cell activation and function in teleosts require collaboration of first and co-stimulatory signals [0.03%]
鱼类T细胞的完全活化和功能需要第一信号与协同刺激信号的合作
Wei Liang,Kang Li,Haiyou Gao et al.
Wei Liang et al.
Mammalian T-cell responses require synergism between the first signal and co-stimulatory signal. However, whether and how dual signaling regulates the T-cell response in early vertebrates remains unknown. In the present study, we discovered...
Surviving winter on the Qinghai-Xizang Plateau: Extensive reversible protein phosphorylation plays a dominant role in regulating hypometabolism in hibernating Nanorana parkeri [0.03%]
青藏高原蛙冬眠生存的分子机制研究：蛋白质可逆磷酸化广泛存在并调控低代谢率形成
Yong-Gang Niu,Deng-Bang Wei,Xue-Jing Zhang et al.
Yong-Gang Niu et al.
Changes in protein abundance and reversible protein phosphorylation (RPP) play important roles in regulating hypometabolism but have never been documented in overwintering frogs at high altitudes. To test the hypothesis that protein abundan...
Jing Cao,Zhen Liu
Jing Cao
Circuit-specific gene therapy is knocking on the door of Parkinson's disease [0.03%]
基于环路的基因治疗敲开了帕金森病治疗的大门
Yue-Qi Wang,Ming Yin,Zhe-Shan Guo
Yue-Qi Wang
Taxonomic revision of genus Rohanixalus (Anura: Rhacophoridae) in China with description of one new species [0.03%]
中国Rohanixalus属蟾蜍的分类修订及一新种描述
Xiao-Long Liu,Jun-Kai Huang,Bryan L Stuart et al.
Xiao-Long Liu et al.
Targeting autophagy in Alzheimer's disease: Animal models and mechanisms [0.03%]
阿尔茨海默病中的自噬调控：动物模型与机制研究
Xiao-Wen Zhang,Xiang-Xing Zhu,Dong-Sheng Tang et al.
Xiao-Wen Zhang et al.
Alzheimer's disease (AD) is an age-related progressive neurodegenerative disorder that leads to cognitive impairment and memory loss. Emerging evidence suggests that autophagy plays an important role in the pathogenesis of AD through the re...