Lung cancer mortality trends in China from 2013 to 2021 and projections to 2030 [0.03%]
中国2013年至2021年肺癌死亡率趋势及2030年前的预测数值
Xin Liang,Xiang Li,Yifei Yao et al.
Xin Liang et al.
Objective: This study was aimed at analyzing temporal trends in lung cancer mortality from 2013 to 2021, and projecting future trends until 2030. Methods:...
From overtreatment to precision: a new clinical standard for DCIS management [0.03%]
从过度治疗到精准治疗：导管原位癌管理的临床新标准
Schlomo Schneebaum
Schlomo Schneebaum
Chinese expert consensus on additional surgery following endoscopic resection for early colorectal cancer (2025 edition) [0.03%]
中国早期结直肠癌内镜切除后补充手术专家共识(2025版)
Zhipeng Qi,Fuqiang Zhao,Xuhua Hu et al.
Zhipeng Qi et al.
Early colorectal cancer is often treated through endoscopic procedures to remove tumors. However, when initial removal is incomplete or shows high-risk features, further major surgery is required to ensure no cancer remains. This consensus ...
Sequential nimotuzumab plus gemcitabine and nab-paclitaxel chemotherapy followed by irreversible electroporation in advanced pancreatic ductal adenocarcinoma: a retrospective real-world analysis [0.03%]
奈莫单抗联合吉西他滨和白蛋白结合型紫杉醇化疗再联合不可逆电穿孔治疗晚期胰腺导管腺癌的序贯方案：一项真实世界回顾性分析
Yang Liu,Dandan Wu,Xing Li et al.
Yang Liu et al.
Mitochondrial uncoupling inhibits serine catabolism via FTO activation in metastatic breast cancer [0.03%]
线粒体解偶联通过激活FTO抑制乳腺癌转移中的丝氨酸分解代谢
Xin Jin,Albert M Li,Man Zhao et al.
Xin Jin et al.
Objective: The mitochondrial serine catabolic pathway (MSCP) supports tumor proliferation and metastasis, yet no therapies target the MSCP. Because cancer cells rely on the MSCP when respiration is suppressed, we hypothes...
Click chemistry-driven tumor theranostics: recent advances, challenges, and future perspectives [0.03%]
点击化学驱动的肿瘤诊疗研究：最近进展、挑战和未来前景
Dayong Hou,Xiangpeng Li,Niyuan Zhang et al.
Dayong Hou et al.
Tumor theranostics, which integrates accurate diagnosis and precise therapy, has emerged as a pivotal approach in modern oncology for improving treatment efficacy and reducing off-target toxicity. Click chemistry, which is characterized by ...
From concept to clinic: emerging paradigms and novel insights into liquid biopsy [0.03%]
从概念到临床：液体活检的新范式和新见解
Wenjie Guo,Yang Liu,Haiying Dong et al.
Wenjie Guo et al.
BEX2 influences the MCL1-Hedgehog signaling axis to regulate the potential of stemness characterization in colorectal cancer [0.03%]
BEX2通过影响MCL1- Hedgehog信号轴调节结直肠癌干细胞特性潜能
Yucheng Qian,Jingsun Wei,Yuan Bian et al.
Yucheng Qian et al.
Objective: Colorectal cancer (CRC) progression is driven by cancer stem cells (CSCs) that evade treatment through dynamic phenotype modulation. Our previous research identified BEX2 as a significant regulator of CRC malig...
Targeting tumor-infiltrating regulatory T cells based on immunometabolism [0.03%]
基于免疫代谢针对肿瘤浸润调节性T细胞的靶向治疗
Na Li,Dexue Tian
Na Li
The immune checkpoint blockade (ICB) approach in cancer therapy involves the disruption of immune checkpoint inhibitory signals on tumor-specific CD8+ T cells, thereby reinstating the immune activity of CD8+ T cells and yielding therapeutic...
Expansion of IL-2-independent tumor-infiltrating lymphocytes through a feeder-free process: a preclinical study for solid tumors [0.03%]
一种无喂养细胞的IL-2非依赖型肿瘤浸润淋巴细胞体外扩增方法及其抗实体瘤效应功能的初步研究
Ying Zhang,Sicheng Du,Rongrui Liu et al.
Ying Zhang et al.
Objective: Conventional tumor-infiltrating lymphocyte (TIL) therapy for solid tumors relies on high-dose interleukin-2 (IL-2) during expansion and post-infusion, and promotes T-cell exhaustion and toxicity. Herein, we dev...