Metabolic engineering of SLC38A2 reprograms glutamine utilization and enhances CAR-macrophage antitumor function in solid tumors [0.03%]
代谢工程改造SLC38A2蛋白可重新编程谷氨酰胺利用并增强实体肿瘤中的CAR-巨噬细胞抗肿瘤功能
Mingzhu Liu,Qingxi Chen,Luoling Zhang et al.
Mingzhu Liu et al.
Objective: This study was aimed at investigating metabolic dysregulation in tumor-associated macrophages (TAMs) in breast cancer and developing a metabolically enhanced chimeric antigen receptor macrophage (CAR-M) strateg...
Surgery-centered integrated strategies for personalized hepatocellular carcinoma care [0.03%]
以手术为中心的肝细胞癌精准治疗综合策略
Yuhan Cui,Zuchao Du,Jiahao Xu et al.
Yuhan Cui et al.
Hepatocellular carcinoma (HCC) remains a major global health burden characterized by late-stage diagnosis and high postoperative recurrence rates. This review presents a surgery-centered precision management framework integrating 3 synergis...
Animal models and pathogenesis of gastric cancer: from premalignant conditions-to-metastasis [0.03%]
动物模型和胃癌的发生机制：从癌前状态到转移
Yumeng Pan,Licong Zhao,Jingyuan Fang
Yumeng Pan
Gastric cancer (GC) remains one of the most prevalent malignancies of the gastrointestinal tract worldwide, ranking fifth in incidence and continuing to be a leading cause of cancer-related mortality. Elucidating the mechanisms underlying G...
Virtual histology imaging of lymph nodes via dynamic full-field optical coherence tomography and deep learning to differentiate metastasis [0.03%]
基于动态全场光学相干层析成像和深度学习的虚拟组织学成像区分淋巴结转移
Shuwei Zhang,Houpu Yang,Yiyin Zhang et al.
Shuwei Zhang et al.
Objective: The current pathological diagnosis of lymph node metastasis is time-consuming, labor-intensive, and dependent on sectioning of paraffin blocks. Herein, in a prospective cohort of patients with breast cancer, we...
Observational Study
Cancer biology & medicine. 2026 Mar 28;23(3):418-429. DOI:10.20892/j.issn.2095-3941.2025.0747 2026
Enhancing FIT-based colorectal cancer screening through risk prediction: a comparative evaluation of 17 models in a large Chinese cohort [0.03%]
基于风险预测改进FIT结直肠癌筛查：在中国大型队列中比较17种模型性能
Le Wang,Weimiao Wu,Bin Liu et al.
Le Wang et al.
Global epidemiology of ovarian cancer: patterns, trends, and risk factors [0.03%]
全球卵巢癌流行病学：特征、趋势和危险因素
Ruyuan Li,Anqi Zhao,Meicen Liu et al.
Ruyuan Li et al.
Ovarian cancer was the eighth most frequently diagnosed cancer among women in 2022. The global age-standardized incidence rate of ovarian cancer decreased from 7.22/100,000 to 6.71/100,000 from 1990 to 2021. However, incidence trends varied...
Lung cancer mortality trends in China from 2013 to 2021 and projections to 2030 [0.03%]
中国2013年至2021年肺癌死亡率趋势及2030年前的预测数值
Xin Liang,Xiang Li,Yifei Yao et al.
Xin Liang et al.
Objective: This study was aimed at analyzing temporal trends in lung cancer mortality from 2013 to 2021, and projecting future trends until 2030. Methods:...
From overtreatment to precision: a new clinical standard for DCIS management [0.03%]
从过度治疗到精准治疗：导管原位癌管理的临床新标准
Schlomo Schneebaum
Schlomo Schneebaum
Chinese expert consensus on additional surgery following endoscopic resection for early colorectal cancer (2025 edition) [0.03%]
中国早期结直肠癌内镜切除后补充手术专家共识(2025版)
Zhipeng Qi,Fuqiang Zhao,Xuhua Hu et al.
Zhipeng Qi et al.
Early colorectal cancer is often treated through endoscopic procedures to remove tumors. However, when initial removal is incomplete or shows high-risk features, further major surgery is required to ensure no cancer remains. This consensus ...
Sequential nimotuzumab plus gemcitabine and nab-paclitaxel chemotherapy followed by irreversible electroporation in advanced pancreatic ductal adenocarcinoma: a retrospective real-world analysis [0.03%]
奈莫单抗联合吉西他滨和白蛋白结合型紫杉醇化疗再联合不可逆电穿孔治疗晚期胰腺导管腺癌的序贯方案：一项真实世界回顾性分析
Yang Liu,Dandan Wu,Xing Li et al.
Yang Liu et al.