SPRED2 suppresses the stemness of hepatocellular carcinoma through the p53/miR-506-3p/KLF4 pathway [0.03%]
SPRED2通过p53/miR-506-3p/KLF4通路抑制肝癌干细胞特性
Tong Gao,Sachio Ito,Aye Moh-Moh-Aung et al.
Tong Gao et al.
Objective: We previously reported that endogenous Sprouty-related, EVH1 domain-containing protein 2 (SPRED2), an inhibitor of the Ras/Raf/ERK-MAPK pathway, controls hepatocellular carcinoma (HCC) cell stemness by downregu...
Innovative cross-intervention: copper ions and metabolic pathways in cancer therapy [0.03%]
创新的跨干预措施：铜离子和代谢途径在癌症治疗中的作用
Lili Niu,Wei Su,Lixia Ju et al.
Lili Niu et al.
Copper ions are essential for cellular function but can induce cytotoxic effects when dysregulated. This review explores the multifaceted role of copper in cancer metabolism with a focus on the novel concept of cuproptosis, a regulated form...
Temporal radiomics for non-invasive preoperative prediction of pathologic complete response to neoadjuvant chemoimmunotherapy in non-small cell lung cancer [0.03%]
用于非小细胞肺癌新辅助化疗免疫治疗术前无创预测病理完全缓解的时序影像组学研究
Sunyi Zheng,Shuo Wang,Ziwei Feng et al.
Sunyi Zheng et al.
Objective: This study aimed to develop and validate a temporal radiomics model based on pre- and post-treatment CT scans for the preoperative prediction of pathologic complete response (pCR) in patients with resectable no...
Migration and invasion inhibitory protein inhibits M2 macrophage polarization to suppress colorectal cancer progression through the STING-NFκB2-IL10 axis [0.03%]
迁移和侵袭抑制蛋白通过STING-NFκB2-IL10轴抑制M2型巨噬细胞极化以抑制结直肠癌进展
Shuai Chen,Chenglu Lu,Jiaxin Li et al.
Shuai Chen et al.
Objective: This study aimed to determine the role and mechanism underlying migration and invasion inhibitory protein (MIIP) modulation in M2 macrophages within the tumor microenvironment and the potential of targeting the...
Multi-cancer early detection: from promise to practice and the next frontier [0.03%]
多癌症早期检测：从前景到实践和未来的前沿方向
Yongjie Xu,Wanqing Chen
Yongjie Xu
Impact of pre-neoadjuvant radioactive iodine seed marking on pathologic complete response and survival in early-stage breast cancer patients [0.03%]
早期乳腺癌患者术前使用碘125粒子标记对病理完全缓解及生存的影响分析
Yihao Geng,Qi Zhang,Zhao Bi et al.
Yihao Geng et al.
Effectiveness of postoperative adjuvant radiochemotherapy versus radiotherapy in thoracic esophageal squamous cell carcinoma with lymph node metastasis: a multicenter randomized study [0.03%]
一项关于淋巴结转移性胸段食管鳞癌患者术后辅助放化疗和单纯放疗疗效的多中心随机研究
Jiangfeng Wang,Wenhui Shen,Xiaojiang Sun et al.
Jiangfeng Wang et al.
Introduction and impact of the young breast cancer in China consensus [0.03%]
中国青年乳腺癌诊治专家共识的制定过程及其影响
Xin Yang,Chao Dong,Qiang Liu
Xin Yang
Cancer stem cells in hepatocellular carcinoma: platforms, updates, challenges and future perspectives [0.03%]
肝癌中的癌症干细胞：平台、更新、挑战和未来展望
Jingyi Lu,Diana Chui-Yee O,Yu-Man Tsui et al.
Jingyi Lu et al.