Neurokinin-1 receptor antagonists in the current management of chemotherapy-induced nausea and vomiting [0.03%]
神经激肽-1受体拮抗剂在化疗引起的恶心呕吐治疗中的应用
Haohua Zhu,Song Huang,Xingsheng Hu
Haohua Zhu
Chemotherapy-induced nausea and vomiting (CINV) is common in patients receiving moderately or highly emetogenic chemotherapy and is caused by the activation of peripheral and central nervous system pathways, with the neurokinin-1 receptor p...
Crigler-Najjar syndrome type 2 complicating cholecystitis in a patient with UGT1A1 gene double homozygous mutations [0.03%]
UGT1A1基因双纯合突变的克里格勒-纳贾尔综合征（2型）合并胆囊炎患者
Jianhui Zhang,Rongrong Chen,Xiang Chen et al.
Jianhui Zhang et al.
Crigler-Najjar syndrome (CNS) and Gilbert syndrome (GS; OMIM: 143500) are rare autosomal recessive diseases that cause unconjugated hyperbilirubinemia due to decreased UGT1A1 enzyme activity. Crigler-Najjar syndrome type 2 (CNS2; OMIM: 6067...
Premature mortality projection for diabetes to 2030: a subnational evaluation towards the Healthy China 2030 Goals [0.03%]
基于《健康中国2030规划纲要》的糖尿病全因死亡趋势地区差异预测至2030年
Hongrui Zhao,Zhenping Zhao,Xuan Yang et al.
Hongrui Zhao et al.
The Healthy China 2030 Plan set the goal of reducing premature deaths from diabetes by 30% by 2030. However, there has been a lack of assessment of premature mortality for diabetes since the action plan was issued. This study used data from...
Research progress on molecular mechanism and future perspectives of leonurine [0.03%]
益母草碱的研究进展及未来展望
Ran Wang,Aiying Li,Zongran Pang
Ran Wang
Leonurus japonicas Houtt., has been recorded as "light body and long life" properties in the oldest classical medicinal book Shennong Bencao Jing thousands of years ago. Herba leonuri, also named Chinese Motherwort or Siberian Motherwort, h...
ALKBH5 exacerbates psoriatic dermatitis in mice by promoting angiogenesis [0.03%]
ALKBH5通过促进血管生成加剧小鼠银屑病皮炎
Chengfang Zhang,Fei Li,Bao Chai et al.
Chengfang Zhang et al.
Psoriasis is a chronic inflammatory skin disease, and its pathogenesis is largely modulated by abnormal angiogenesis. Previous research has indicated that AlkB homolog 5 (ALKBH5), an important demethylase affecting N6-methyladenosine (m6A) ...
Anti-angiogenic therapy as a beacon of hope in the battle against pulmonary NUT midline carcinoma [0.03%]
抗血管生成疗法在对抗肺NUT中线癌战役中带来希望的灯塔
Linyan Tian,Siyu Lei,Yaning Yang et al.
Linyan Tian et al.
Primary pulmonary nuclear protein of the testis (NUT) midline carcinoma (NMC) is a rare and highly aggressive thoracic malignancy that poses significant diagnostic and therapeutic challenges in clinical practice. This tumor is characterized...
Long-acting lenacapavir is a breakthrough for preventing HIV infection, but HIV vaccine research must continue [0.03%]
长效LENACAPAVIR防治艾滋感染具突破性 但研发艾滋疫苗仍须继续
Caijun Sun,Linghua Li,Pingchao Li et al.
Caijun Sun et al.
Correlation of enzyme activities and genotype with clinical manifestations in Chinese patients of different sexes with classical and late-onset Fabry disease [0.03%]
中国不同性别经典型和晚发型法布雷病患者酶活性及基因型与临床表型相关性研究
Wenkai Guo,Yuansheng Xie,Pengcheng Ji et al.
Wenkai Guo et al.
Fabry disease, a rare genetic disorder affecting multiple organs, has understudied correlations among enzyme activity, genotype, and clinical manifestations in patients of different sexes with classical and late-onset phenotypes. In this st...
Progress of research on the gut microbiome and its metabolite short-chain fatty acids in postmenopausal osteoporosis: a literature review [0.03%]
绝经后骨质疏松症肠道微生态及短链脂肪酸研究进展：文献综述
Yao Chen,Ying Xie,Xijie Yu
Yao Chen
Postmenopausal osteoporosis (PMOP) is a systemic metabolic bone disease caused by the decrease in estrogen levels after menopause. It leads to bone loss, microstructural damage, and an increased risk of fractures. Studies have found that th...
Determining the biomarkers and pathogenesis of myocardial infarction combined with ankylosing spondylitis via a systems biology approach [0.03%]
通过系统生物学方法确定心肌梗死合并强直性脊柱炎的生物标志物及发病机制
Chunying Liu,Chengfei Peng,Xiaodong Jia et al.
Chunying Liu et al.
Ankylosing spondylitis (AS) is linked to an increased prevalence of myocardial infarction (MI). However, research dedicated to elucidating the pathogenesis of AS-MI is lacking. In this study, we explored the biomarkers for enhancing the dia...