Mutually reinforcing relationship between Sjögren's syndrome and lung adenocarcinoma: insights from Mendelian randomisation, single-cell, and transcriptomic analyses [0.03%]
Mendelian随机化、单细胞和转录组分析揭示的原发性干燥综合征与肺腺癌相互促进的关系
Kai Xu,Manhua Wang,Zixuan Yang et al.
Kai Xu et al.
Increasing evidence suggests an association between Sjögren's syndrome (SS) and multiple cancers; however, the causal relationships and regulatory mechanisms remain unclear. Using European genome-wide association study data, we employed Me...
Risk factors for mortality in neonatal ARDS: a multicenter retrospective cohort study in China [0.03%]
中国新生儿ARDS死亡危险因素的多中心回顾性队列研究
Yang Yang,Chuchu Guo,Yunsu Zou et al.
Yang Yang et al.
As a life-threatening respiratory syndrome, epidemiological data from China has shown that the mortality rate of neonatal acute respiratory distress syndrome (ARDS) is as high as 12.5%. Nevertheless, studies on the influencing factors of th...
RRS1 regulates proliferation, migration, and invasion of HTR-8/SVneo human trophoblasts [0.03%]
RRS1调节HTR-8/SVneo人绒毛膜促性腺激素的增殖、迁移和侵袭
Yixuan Wu,Yao Li,Jing Wang et al.
Yixuan Wu et al.
Trophoblast cells serve as the foundation for placental development. We analyzed published multiomics sequencing data and found that trophoblast cells highly expressed RRS1 compared to primitive endoderm and epiblast. We used HTR-8/SVneo ce...
Nan Zhang,Hongye Xu,Hongjian Zhang et al.
Nan Zhang et al.
Acute ischemic stroke (AIS) is a cerebrovascular disease characterized by high morbidity, disability, and mortality, posing a significant threat to human health. Endovascular treatment has now been established as a key method for AIS manage...
Precision medicine for advanced biliary tract cancer in China: current status and future perspectives [0.03%]
中国晚期胆道癌精准医疗的现状及未来展望
Zhen Huang,Wen Zhang,Yongkun Sun et al.
Zhen Huang et al.
Biliary tract cancer (BTC) is a rare group of malignancies that develop from the epithelial lining of the biliary tree and have a poor prognosis. Although chemotherapy is the standard of care for patients with advanced BTC in China, its cli...
Albumin-bound paclitaxel plus anlotinib in patients with recurrent, platinum-resistant primary epithelial ovarian cancer (A-Plus): a phase II, single-arm, prospective study [0.03%]
白蛋白结合型紫杉醇联合安罗替尼治疗复发性铂耐药原发性上皮卵巢癌患者：一项Ⅱ期、单组、前瞻性研究
Yun Zhou,Jian Zhou,Yin Wang et al.
Yun Zhou et al.
This study aimed to evaluate the efficacy and safety of combining albumin-bound paclitaxel (abpaclitaxel) and anlotinib for ovarian cancer. In this study, 44 patients diagnosed with platinum-resistant ovarian cancer were enrolled. Patients ...
Perspective on strengthening dementia prevention and control system: a comprehensive framework for national health [0.03%]
痴呆预防控制体系强化策略——国家健康框架下的顶层设计与综合干预框架透视
Bin Cong,Hengge Xie,Yongan Sun et al.
Bin Cong et al.
Particulate matter exposure and end-stage renal disease risk in IgA nephropathy [0.03%]
颗粒物暴露与IgA肾病患者终末期肾病风险的关系
Yilin Chen,Huan Zhou,Siqing Wang et al.
Yilin Chen et al.
Long-term exposure to particulate matter has been increasingly implicated in the progression of chronic kidney disease (CKD). However, its impact on IgA nephropathy (IgAN), a leading cause of end-stage renal disease (ESRD), remains unclear....
Global, regional and national burden and trends of congenital musculoskeletal and limb deformities among under-5 children from 1990 to 2021: a systematic analysis for the Global Burden of Disease Study 2021 [0.03%]
1990至2021年全球、区域和国家5岁以下儿童先天性骨骼肌肉和肢体畸形疾病负担及变化趋势：2021年全球疾病负担研究系统分析
Qinglin Yang,Zhuanmei Jin,Yongping Wang
Qinglin Yang
Congenital musculoskeletal and limb deformities (CMLD) seriously affect the physical and mental health of patients, and pose great challenges to healthcare systems worldwide. We explored the specific situation and changes of incidence, prev...
Predictive biomarkers for immunotherapy in nasopharyngeal carcinoma: from tumor microenvironment to macroenvironment [0.03%]
鼻咽癌免疫治疗预测性生物标志物研究：从肿瘤微环境到宏观环境
Saiwei Huang,Yelin Liang,Na Liu et al.
Saiwei Huang et al.
The introduction of PD-1 blockades to chemotherapy and radiotherapy has shown promising outcomes in patients with nasopharyngeal carcinoma, but anti-PD-1 therapies are only effective in a small proportion of patients, indicating the need fo...