Cellular senescence in age-related musculoskeletal diseases: intercellular communication as a driver of disease pathogenesis [0.03%]
细胞衰老在年龄相关肌肉骨骼疾病中的作用：细胞间通讯驱动疾病的发病机制
Ilya Klabukov,Elizabeth Skornyakova,Daria Eygel et al.
Ilya Klabukov et al.
Clinical trial landscape of malignant peripheral nerve sheath tumors: challenges and opportunities [0.03%]
恶性周围神经鞘肿瘤的临床试验现状：挑战与机遇
Guo Zhao,Yale Jiang,Jiaxiu Ma et al.
Guo Zhao et al.
Association of oral frailty and gut microbiota with hypertension: cross-sectional results in the Shika study [0.03%]
口腔衰弱和肠道菌群与高血压的关系——来自Shika研究的横断面结果分析
Fumihiko Suzuki,Ren Mizoguchi,Shigehiro Karashima et al.
Fumihiko Suzuki et al.
Although recent studies have reported the association between toxins produced by certain gut microbiota and elevated blood pressure, the relationship between oral frailty (OF) and gut microbiota has rarely been investigated. The purpose of ...
Prognostic value of ultrafiltration rate variability in maintenance hemodialysis patients: a prospective cohort study [0.03%]
血透患者超滤率变异性的预后价值：前瞻性队列研究
Jinbo Yu,Xiaohong Chen,Wuhua Jiang et al.
Jinbo Yu et al.
This single-center prospective cohort study establishes ultrafiltration rate variability (quantified by coefficient of variation, UFRCV) as an independent predictor of all-cause and cardiovascular mortality in maintenance hemodialysis patie...
Yinqiao powder effectively alleviates acute lung injury via regulating cGAS-STING signaling pathway [0.03%]
银翘解毒片通过调节cGAS-STING信号通路有效缓解急性肺损伤
Hui Li,Jincai Wen,Yuanyuan Cui et al.
Hui Li et al.
Acute lung injury (ALI) is a respiratory disease characterized by inflammation. Yinqiao powder (YQP) is a traditional Chinese medicinal compound, extensively used for its heat-clearing and detoxifying effects. It is usually used clinically ...
Metabolic biomarkers for predicting onset and severity of CAR-T therapy-induced cytokine release syndrome in multiple myeloma [0.03%]
代谢生物标志物可预测CAR-T治疗诱导的多发性骨髓瘤患者的细胞因子释放综合症的发生及严重程度
Xiaolin Ma,Tuantuan Gui,Shuangshuang Yang et al.
Xiaolin Ma et al.
Chimeric antigen receptor T-cell (CAR-T) therapy has been successfully applied in clinical treatment, especially for hematologic malignancies such as multiple myeloma (MM), but its broad application is limited by cytokine release syndrome (...
Qi Li,Ning Zhao,Ruitao Hou et al.
Qi Li et al.
Chimeric antigen receptor T (CAR-T) cells demonstrate remarkable effectiveness in targeting and eliminating pathogenic B-cell lineages, showing significant specificity and efficacy against B cell malignancies. In addition, CAR-T cell-mediat...
Current state of bioceramic bone repair materials in immune regulation: a review [0.03%]
生物陶瓷骨修复材料的免疫调节作用研究进展综述
Yuhang Hu,Yi Xu,Qifan Shen et al.
Yuhang Hu et al.
Extensive bone defects represent a significant clinical challenge, often leading to severe impairment of patients function and quality of life. Traditional treatments, such as autografts and allografts, are widely used but have notable limi...
Sequential development of three syndromes in a patient with m.3243A>G mutation: a case report [0.03%]
一例m.3243A>G突变患者先后出现三种综合征的病例报告
Guoling Zeng,Rongpei Liu,Xiaotian Li et al.
Guoling Zeng et al.
Mitochondrial disorders are highly heterogeneous and can manifest as a spectrum of clinically heterogeneous disorders that affect multiple organ systems. Herein, we report a Chinese female patient carrying mitochondrial DNA m.3243A>G mutati...
Plasma cell development-based prediction of prognosis and treatment response in individual multiple myeloma [0.03%]
基于浆细胞发育的个体多发性骨髓瘤预后及治疗反应的预测模型
Sitao Jiang,Yuan Yang,Man Yao et al.
Sitao Jiang et al.
We hypothesized that gene networks converged between plasma cell development and multiple myeloma (MM) pathogenesis may better explain the clinical heterogeneity in individual MM patients. Here, we transformed the reciprocal expression patt...